The adaptor molecule Disabled-2 links the transforming growth factor beta receptors to the Smad pathway.
about
Disabled-2 (Dab2) is required for transforming growth factor beta-induced epithelial to mesenchymal transition (EMT)Identification of novel VHL target genes and relationship to hypoxic response pathwaysRegulation of the Wnt signaling pathway by disabled-2 (Dab2)Disabled-2 (Dab2) inhibits Wnt/β-catenin signalling by binding LRP6 and promoting its internalization through clathrinLocal network topology in human protein interaction data predicts functional associationDisabled-2 exhibits the properties of a cargo-selective endocytic clathrin adaptorDual roles for the Dab2 adaptor protein in embryonic development and kidney transportTLP, a novel modulator of TGF-beta signaling, has opposite effects on Smad2- and Smad3-dependent signalingTGF-β control of stem cell differentiation genesGene expression study of monocytes/macrophages during early foreign body reaction and identification of potential precursors of myofibroblastsDisabled-2 is required for efficient hemostasis and platelet activation by thrombin in miceCrystal structures of the Dab homology domains of mouse disabled 1 and 2Structure, sulfatide binding properties, and inhibition of platelet aggregation by a disabled-2 protein-derived peptide.The adaptor protein Disabled-2: new insights into platelet biology and integrin signalingEndocytosis and Physiology: Insights from Disabled-2 Deficient MiceSwitching Roles of TGF-β in Cancer Development: Implications for Therapeutic Target and Biomarker StudiesCell-type-specific activation of PAK2 by transforming growth factor beta independent of Smad2 and Smad3Cell cycle-dependent phosphorylation of Disabled-2 by cdc2bcn-1 Element-dependent activation of the laminin gamma 1 chain gene by the cooperative action of transcription factor E3 (TFE3) and Smad proteinsEndofin, a FYVE domain protein, interacts with Smad4 and facilitates transforming growth factor-beta signalingDab2 stabilizes Axin and attenuates Wnt/beta-catenin signaling by preventing protein phosphatase 1 (PP1)-Axin interactionsDisabled-2 is transcriptionally regulated by ICSBP and augments macrophage spreading and adhesion.miR-145 is differentially regulated by TGF-β1 and ischaemia and targets Disabled-2 expression and wnt/β-catenin activityRegulation of myosin-VI targeting to endocytic compartmentsType II transforming growth factor-beta receptor recycling is dependent upon the clathrin adaptor protein Dab2NetSlim: high-confidence curated signaling mapsA single common portal for clathrin-mediated endocytosis of distinct cargo governed by cargo-selective adaptors.A novel transforming growth factor-beta receptor-interacting protein that is also a light chain of the motor protein dynein.Hematopoietic gene expression profile in zebrafish kidney marrow.Endogenous transforming growth factor-beta receptor-mediated Smad signaling complexes analyzed by mass spectrometry.Xenopus Dab2 is required for embryonic angiogenesisDynamic expression of Dab2 in the mouse embryonic central nervous system.The tale of transforming growth factor-beta (TGFbeta) signaling: a soigné enigma.The inhibitory effects of Disabled-2 (Dab2) on Wnt signaling are mediated through Axin.Mechanisms of the epithelial-mesenchymal transition by TGF-betaTGF-beta signalling in the adult neurogenic niche promotes stem cell quiescence as well as generation of new neurons.Loss of disabled-2 expression is an early event in esophageal squamous tumorigenesis.Epigenetic downregulation of human disabled homolog 2 switches TGF-beta from a tumor suppressor to a tumor promoter.Disabled-2 downregulation promotes epithelial-to-mesenchymal transitionHormonal induction and roles of Disabled-2 in lactation and involution.
P2860
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P2860
The adaptor molecule Disabled-2 links the transforming growth factor beta receptors to the Smad pathway.
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
name
The adaptor molecule Disabled- ...... receptors to the Smad pathway
@nl
The adaptor molecule Disabled- ...... receptors to the Smad pathway.
@ast
The adaptor molecule Disabled- ...... receptors to the Smad pathway.
@en
The adaptor molecule Disabled- ...... receptors to the Smad pathway.
@en-gb
type
label
The adaptor molecule Disabled- ...... receptors to the Smad pathway
@nl
The adaptor molecule Disabled- ...... receptors to the Smad pathway.
@ast
The adaptor molecule Disabled- ...... receptors to the Smad pathway.
@en
The adaptor molecule Disabled- ...... receptors to the Smad pathway.
@en-gb
prefLabel
The adaptor molecule Disabled- ...... receptors to the Smad pathway
@nl
The adaptor molecule Disabled- ...... receptors to the Smad pathway.
@ast
The adaptor molecule Disabled- ...... receptors to the Smad pathway.
@en
The adaptor molecule Disabled- ...... receptors to the Smad pathway.
@en-gb
P2093
P2860
P921
P3181
P356
P1433
P1476
The adaptor molecule Disabled- ...... receptors to the Smad pathway.
@en
P2093
P2860
P304
P3181
P356
10.1093/EMBOJ/20.11.2789
P407
P577
2001-06-01T00:00:00Z