TIN2 is a tankyrase 1 PARP modulator in the TRF1 telomere length control complex
about
POT1-interacting protein PIP1: a telomere length regulator that recruits POT1 to the TIN2/TRF1 complexA critical role for TPP1 and TIN2 interaction in high-order telomeric complex assemblyProtein requirements for sister telomere association in human cellsStructural basis of selective ubiquitination of TRF1 by SCFFbx4Telosome, a mammalian telomere-associated complex formed by multiple telomeric proteinsTelomerase inhibitor PinX1 provides a link between TRF1 and telomerase to prevent telomere elongationIn vivo stoichiometry of shelterin componentsHuman protection of telomeres 1 (POT1) is a negative regulator of telomerase activity in vitroFinding the end: recruitment of telomerase to telomeresTIN2-tethered TPP1 recruits human telomerase to telomeres in vivoRegulating telomere length from the inside out: the replication fork modelCell biology of disease: Telomeropathies: an emerging spectrum disorderTranscriptional activation of TINF2, a gene encoding the telomere-associated protein TIN2, by Sp1 and NF-κB factorsDNA-damage response and repair activities at uncapped telomeres depend on RNF8Telomere protection by TPP1/POT1 requires tethering to TIN2A novel form of the telomere-associated protein TIN2 localizes to the nuclear matrixWRN is recruited to damaged telomeres via its RQC domain and tankyrase1-mediated poly-ADP-ribosylation of TRF1.The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.Mice with bad ends: mouse models for the study of telomeres and telomerase in cancer and aging.Crosstalk between telomere maintenance and radiation effects: A key player in the process of radiation-induced carcinogenesis.Differences in disease severity but similar telomere lengths in genetic subgroups of patients with telomerase and shelterin mutations.TRF1 and TRF2 differentially modulate Rad51-mediated telomeric and nontelomeric displacement loop formation in vitroGenetics of familial melanoma: 20 years after CDKN2A.Coordinate regulation between expression levels of telomere-binding proteins and telomere length in breast carcinomasCaenorhabditis elegans POT-1 and POT-2 repress telomere maintenance pathways.Telomeres and aging.Cell cycle regulated phosphorylation of the telomere-associated protein TIN2Poly-ADP ribosylation of PTEN by tankyrases promotes PTEN degradation and tumor growthCharacterization of RanBPM molecular determinants that control its subcellular localization.TIN2 protein dyskeratosis congenita missense mutants are defective in association with telomerase.Nonsense mutations in the shelterin complex genes ACD and TERF2IP in familial melanomaDyskeratosis congenita as a disorder of telomere maintenance.Tankyrase-1 function at telomeres and during mitosis is regulated by Polo-like kinase-1-mediated phosphorylation.Constitutional and acquired autosomal aneuploidyThe Shelterin TIN2 Subunit Mediates Recruitment of Telomerase to Telomeres.Polo-like Kinase 1 (Plk1) Up-regulates Telomerase Activity by Affecting Human Telomerase Reverse Transcriptase (hTERT) Stability.Trypanosoma brucei TIF2 and TRF Suppress VSG Switching Using Overlapping and Independent MechanismsPoly(ADP-ribosylation) and genomic stability.Cyclin D3/CDK11p58 complex is involved in the repression of androgen receptor.The telomeric PARP, tankyrases, as targets for cancer therapy
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P2860
TIN2 is a tankyrase 1 PARP modulator in the TRF1 telomere length control complex
description
2004 nî lūn-bûn
@nan
2004 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
TIN2 is a tankyrase 1 PARP modulator in the TRF1 telomere length control complex
@ast
TIN2 is a tankyrase 1 PARP modulator in the TRF1 telomere length control complex
@en
TIN2 is a tankyrase 1 PARP modulator in the TRF1 telomere length control complex
@en-gb
TIN2 is a tankyrase 1 PARP modulator in the TRF1 telomere length control complex
@nl
type
label
TIN2 is a tankyrase 1 PARP modulator in the TRF1 telomere length control complex
@ast
TIN2 is a tankyrase 1 PARP modulator in the TRF1 telomere length control complex
@en
TIN2 is a tankyrase 1 PARP modulator in the TRF1 telomere length control complex
@en-gb
TIN2 is a tankyrase 1 PARP modulator in the TRF1 telomere length control complex
@nl
prefLabel
TIN2 is a tankyrase 1 PARP modulator in the TRF1 telomere length control complex
@ast
TIN2 is a tankyrase 1 PARP modulator in the TRF1 telomere length control complex
@en
TIN2 is a tankyrase 1 PARP modulator in the TRF1 telomere length control complex
@en-gb
TIN2 is a tankyrase 1 PARP modulator in the TRF1 telomere length control complex
@nl
P2860
P921
P3181
P356
P1433
P1476
TIN2 is a tankyrase 1 PARP modulator in the TRF1 telomere length control complex
@en
P2093
Jeffrey Zheng-Sheng Ye
P2860
P2888
P304
P3181
P356
10.1038/NG1360
P407
P577
2004-06-01T00:00:00Z
P5875
P6179
1044674857