ATF4 is a mediator of the nutrient-sensing response pathway that activates the human asparagine synthetase gene
about
Mitosin/CENP-F as a negative regulator of activating transcription factor-4Induction of Grp78/BiP by translational block: activation of the Grp78 promoter by ATF4 through and upstream ATF/CRE site independent of the endoplasmic reticulum stress elementsC/EBP homology protein (CHOP) interacts with activating transcription factor 4 (ATF4) and negatively regulates the stress-dependent induction of the asparagine synthetase geneCharacterization of the amino acid response element within the human sodium-coupled neutral amino acid transporter 2 (SNAT2) System A transporter geneThe p300/CBP-associated factor (PCAF) is a cofactor of ATF4 for amino acid-regulated transcription of CHOPTime- and dose-dependent effects of curcumin on gene expression in human colon cancer cellsArgininosuccinate synthetase from the urea cycle to the citrulline-NO cycleActivating transcription factor 3 is integral to the eukaryotic initiation factor 2 kinase stress responseGlutamine-mediated dual regulation of heat shock transcription factor-1 activation and expressionKDM4C and ATF4 Cooperate in Transcriptional Control of Amino Acid MetabolismThe eIF2 kinase GCN2 is essential for the murine immune system to adapt to amino acid deprivation by asparaginaseDissection of a QTL hotspot on mouse distal chromosome 1 that modulates neurobehavioral phenotypes and gene expression.Circulating tumour cells demonstrate an altered response to hypoxia and an aggressive phenotype.Decreased ATF4 expression as a mechanism of acquired resistance to long-term amino acid limitation in cancer cellsThe transcription factor ATF4 promotes skeletal myofiber atrophy during fasting.Amino acid availability controls TRB3 transcription in liver through the GCN2/eIF2α/ATF4 pathwayActivation of the amino acid response modulates lineage specification during differentiation of murine embryonic stem cells.p53 and ATF4 mediate distinct and additive pathways to skeletal muscle atrophy during limb immobilization.A mitogen-activated protein kinase/extracellular signal-regulated kinase kinase (MEK)-dependent transcriptional program controls activation of the early growth response 1 (EGR1) gene during amino acid limitationBoth transcriptional regulation and translational control of ATF4 are central to the integrated stress response.Asparagine synthetase: regulation by cell stress and involvement in tumor biologyUpregulation of the coagulation factor VII gene during glucose deprivation is mediated by activating transcription factor 4.Asparagine synthetase chemotherapy.Stress-induced translation of ATF5 mRNA is regulated by the 5'-untranslated region.Functional analysis of a novel DNA polymorphism of a tandem repeated sequence in the asparagine synthetase gene in acute lymphoblastic leukemia cells.MAPK signaling triggers transcriptional induction of cFOS during amino acid limitation of HepG2 cells.Dickkopf homolog 1, a Wnt signaling antagonist, is transcriptionally up-regulated via an ATF4-independent and MAPK/ERK-dependent pathway following amino acid deprivationHuman CHAC1 Protein Degrades Glutathione, and mRNA Induction Is Regulated by the Transcription Factors ATF4 and ATF3 and a Bipartite ATF/CRE Regulatory ElementLysine and Leucine Deficiencies Affect Myocytes Development and IGF Signaling in Gilthead Sea Bream (Sparus aurata).Evidence of Alternative Cystatin C Signal Sequence Cleavage Which Is Influenced by the A25T Polymorphism.Transcriptional repression of ATF4 gene by CCAAT/enhancer-binding protein β (C/EBPβ) differentially regulates integrated stress response.Nutritional control of gene expression: how mammalian cells respond to amino acid limitation.ATF4-dependent regulation of the JMJD3 gene during amino acid deprivation can be rescued in Atf4-deficient cells by inhibition of deacetylation.ATF4 is an oxidative stress-inducible, prodeath transcription factor in neurons in vitro and in vivo.ATF4-dependent transcription mediates signaling of amino acid limitation.Deprivation of protein or amino acid induces C/EBPbeta synthesis and binding to amino acid response elements, but its action is not an absolute requirement for enhanced transcription.Alignment of the transcription start site coincides with increased transcriptional activity from the human asparagine synthetase gene following amino acid deprivation of HepG2 cells.Transcriptional induction of the human asparagine synthetase gene during the unfolded protein response does not require the ATF6 and IRE1/XBP1 arms of the pathwayInteraction of RNA-binding proteins HuR and AUF1 with the human ATF3 mRNA 3'-untranslated region regulates its amino acid limitation-induced stabilization.ATF4-dependent transcription is a key mechanism in VEGF up-regulation by oxidized phospholipids: critical role of oxidized sn-2 residues in activation of unfolded protein response.
P2860
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P2860
ATF4 is a mediator of the nutrient-sensing response pathway that activates the human asparagine synthetase gene
description
2002 nî lūn-bûn
@nan
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2002年の論文
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2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
ATF4 is a mediator of the nutr ...... man asparagine synthetase gene
@ast
ATF4 is a mediator of the nutr ...... man asparagine synthetase gene
@en
ATF4 is a mediator of the nutr ...... man asparagine synthetase gene
@en-gb
ATF4 is a mediator of the nutr ...... man asparagine synthetase gene
@nl
type
label
ATF4 is a mediator of the nutr ...... man asparagine synthetase gene
@ast
ATF4 is a mediator of the nutr ...... man asparagine synthetase gene
@en
ATF4 is a mediator of the nutr ...... man asparagine synthetase gene
@en-gb
ATF4 is a mediator of the nutr ...... man asparagine synthetase gene
@nl
prefLabel
ATF4 is a mediator of the nutr ...... man asparagine synthetase gene
@ast
ATF4 is a mediator of the nutr ...... man asparagine synthetase gene
@en
ATF4 is a mediator of the nutr ...... man asparagine synthetase gene
@en-gb
ATF4 is a mediator of the nutr ...... man asparagine synthetase gene
@nl
P2093
P2860
P3181
P356
P1476
ATF4 is a mediator of the nutr ...... man asparagine synthetase gene
@en
P2093
Michael S Kilberg
Perry J Bain
Rene LeBlanc-Chaffin
P2860
P304
P3181
P356
10.1074/JBC.M201959200
P407
P577
2002-07-05T00:00:00Z