OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis
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OTULIN antagonizes LUBAC signaling by specifically hydrolyzing Met1-linked polyubiquitinOTULIN restricts Met1-linked ubiquitination to control innate immune signalingDUBbing Cancer: Deubiquitylating Enzymes Involved in Epigenetics, DNA Damage and the Cell Cycle As Therapeutic TargetsMass Spectrometry-Based Proteomics for Investigating DNA Damage-Associated Protein UbiquitylationPoly-ubiquitination in TNFR1-mediated necroptosisSubstrate specificity of the ubiquitin and Ubl proteasesUbiquitin modificationsRole of Deubiquitinating Enzymes in DNA RepairRegulation of Met1-linked polyubiquitin signalling by the deubiquitinase OTULINFine-tuning the ubiquitin code at DNA double-strand breaks: deubiquitinating enzymes at workOptimising methods for the preservation, capture and identification of ubiquitin chains and ubiquitylated proteins by immunoblottingDeubiquitinating enzymes in cellular signaling and disease regulationQuantifying ubiquitin signalingViral OTU deubiquitinases: a structural and functional comparisonStructural Basis for Ovarian Tumor Domain-containing Protein 1 (OTU1) Binding to p97/Valosin-containing Protein (VCP)Structure and Catalytic Regulatory Function of Ubiquitin Specific Protease 11 N-Terminal and Ubiquitin-like DomainsMolecular Basis and Regulation of OTULIN-LUBAC InteractionPeeling away the layers of ubiquitin signaling complexities with synthetic ubiquitin-protein conjugates.Mode of substrate recognition by the Josephin domain of ataxin-3, which has an endo-type deubiquitinase activityGenetically Directed Production of Recombinant, Isosteric and Nonhydrolysable Ubiquitin ConjugatesMolecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne.MINDY-1 Is a Member of an Evolutionarily Conserved and Structurally Distinct New Family of Deubiquitinating Enzymes.Linear ubiquitination in immunityDeubiquitylase OTUD3 regulates PTEN stability and suppresses tumorigenesisVCP/p97 cooperates with YOD1, UBXD1 and PLAA to drive clearance of ruptured lysosomes by autophagy.Noncanonical regulation of alkylation damage resistance by the OTUD4 deubiquitinase.YOD1/TRAF6 association balances p62-dependent IL-1 signaling to NF-κBDeubiquitinating enzymes Ubp2 and Ubp15 regulate endocytosis by limiting ubiquitination and degradation of ARTsLysine 27 ubiquitination of the mitochondrial transport protein Miro is dependent on serine 65 of the Parkin ubiquitin ligaseNecroptosisAssembly and specific recognition of k29- and k33-linked polyubiquitin.Deubiquitinase OTUD6B Isoforms Are Important Regulators of Growth and Proliferation.Quantitative proteomics reveal a feedforward mechanism for mitochondrial PARKIN translocation and ubiquitin chain synthesis.Cezanne (OTUD7B) regulates HIF-1α homeostasis in a proteasome-independent manner.USP8 regulates mitophagy by removing K6-linked ubiquitin conjugates from parkinA20 restricts ubiquitination of pro-interleukin-1β protein complexes and suppresses NLRP3 inflammasome activity.The IκB kinase complex in NF-κB regulation and beyond.Deubiquitinating enzyme specificity for ubiquitin chain topology profiled by di-ubiquitin activity probesOTUB1 de-ubiquitinating enzyme promotes prostate cancer cell invasion in vitro and tumorigenesis in vivo.Ubiquitin acetylation inhibits polyubiquitin chain elongation.
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P2860
OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis
description
2013 nî lūn-bûn
@nan
2013 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
OTU deubiquitinases reveal mec ...... tin chain restriction analysis
@ast
OTU deubiquitinases reveal mec ...... tin chain restriction analysis
@en
OTU deubiquitinases reveal mec ...... tin chain restriction analysis
@en-gb
OTU deubiquitinases reveal mec ...... tin chain restriction analysis
@nl
type
label
OTU deubiquitinases reveal mec ...... tin chain restriction analysis
@ast
OTU deubiquitinases reveal mec ...... tin chain restriction analysis
@en
OTU deubiquitinases reveal mec ...... tin chain restriction analysis
@en-gb
OTU deubiquitinases reveal mec ...... tin chain restriction analysis
@nl
altLabel
OTU Deubiquitinases Reveal Mec ...... tin Chain Restriction Analysis
@en
prefLabel
OTU deubiquitinases reveal mec ...... tin chain restriction analysis
@ast
OTU deubiquitinases reveal mec ...... tin chain restriction analysis
@en
OTU deubiquitinases reveal mec ...... tin chain restriction analysis
@en-gb
OTU deubiquitinases reveal mec ...... tin chain restriction analysis
@nl
P2093
P2860
P50
P921
P3181
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OTU deubiquitinases reveal mec ...... tin chain restriction analysis
@en
P2093
Farid El Oualid
Masato Akutsu
Nadia Arnaudo
Reggy Ekkebus
Stefan M V Freund
Tobias Wauer
Tycho E T Mevissen
P2860
P304
P3181
P356
10.1016/J.CELL.2013.05.046
P407
P577
2013-07-03T00:00:00Z