Displacement of corticotropin releasing factor from its binding protein as a possible treatment for Alzheimer's disease
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Residues of corticotropin releasing factor-binding protein (CRF-BP) that selectively abrogate binding to CRF but not to urocortin 1Sculpting the hippocampus from within: stress, spines, and CRHA single amino acid serves as an affinity switch between the receptor and the binding protein of corticotropin-releasing factor: implications for the design of agonists and antagonistsPhysiology, pharmacology, and therapeutic relevance of urocortins in mammals: ancient CRF paralogs.Corticotropin-releasing factor in the basolateral amygdala enhances memory consolidation via an interaction with the beta-adrenoceptor-cAMP pathway: dependence on glucocorticoid receptor activation.Oreochromis mossambicus (tilapia) corticotropin-releasing hormone: cDNA sequence and bioactivity.A ventral tegmental CRF-glutamate-dopamine interaction in addiction.Abnormal dendritic maturation of developing cortical neurons exposed to corticotropin releasing hormone (CRH): Insights into effects of prenatal adversity?Effects of stress and stress hormones on amyloid-beta protein and plaque deposition.Stress-induced tau phosphorylation: functional neuroplasticity or neuronal vulnerability?Corticotropin-releasing hormone (CRH) downregulates the function of its receptor (CRF1) and induces CRF1 expression in hippocampal and cortical regions of the immature rat brain.The binding protein of corticotropin-releasing factor: ligand-binding site and subunit structureInvolvement of stress-released corticotropin-releasing hormone in the basolateral amygdala in regulating memory consolidation.Effects of corticotrophin-releasing factor receptor 1 antagonists on amyloid-β and behavior in Tg2576 mice.Stress and the developing hippocampus: a double-edged sword?Immunocytochemical distribution of corticotropin-releasing hormone receptor type-1 (CRF(1))-like immunoreactivity in the mouse brain: light microscopy analysis using an antibody directed against the C-terminus.Neuronal activity and stress differentially regulate hippocampal and hypothalamic corticotropin-releasing hormone expression in the immature ratDifferential regulation of the expression of corticotropin-releasing factor receptor type 2 (CRF2) in hypothalamus and amygdala of the immature rat by sensory input and food intake.Activation of specific neuronal circuits by corticotropin releasing hormone as indicated by c-fos expression and glucose metabolism.Infantile spasms: hypothesis-driven therapy and pilot human infant experiments using corticotropin-releasing hormone receptor antagonists.Chemical neuroimmunology: health in a nutshell bidirectional communication between immune and stress (limbic-hypothalamic-pituitary-adrenal) systems.Cortagine, a specific agonist of corticotropin-releasing factor receptor subtype 1, is anxiogenic and antidepressive in the mouse model.Targeted disruption of the orphanin FQ/nociceptin gene increases stress susceptibility and impairs stress adaptation in mice.Altered anxiety and weight gain in corticotropin-releasing hormone-binding protein-deficient miceImpact of CRFR1 Ablation on Amyloid-β Production and Accumulation in a Mouse Model of Alzheimer's Disease.Displacement of insulin-like growth factors from their binding proteins as a potential treatment for stroke.Corticotropin Releasing Factor Binding Protein and CRF2 Receptors in the Ventral Tegmental Area: Modulation of Ethanol Binge Drinking in C57BL/6J MiceThe CRF1 receptor mediates the excitatory actions of corticotropin releasing factor (CRF) in the developing rat brain: in vivo evidence using a novel, selective, non-peptide CRF receptor antagonistInhibition of pituitary-adrenal secretion by a corticotropin releasing hormone antagonist in humans.Impairment of synaptic plasticity by the stress mediator CRH involves selective destruction of thin dendritic spines via RhoA signalingCorticotrophin releasing factor accelerates neuropathology and cognitive decline in a mouse model of Alzheimer's disease.Regulation of synaptic transmission by CRF receptors.The central corticotropin releasing factor system during development and adulthood.Corticotropin-releasing factor-binding protein ligand inhibitor blunts excessive weight gain in genetically obese Zucker rats and rats during nicotine withdrawalFear extinction learning can be impaired or enhanced by modulation of the CRF system in the basolateral nucleus of the amygdala.Corticotropin releasing factor in neuroplasticity.Tracheal occlusion conditioning in conscious rats modulates gene expression profile of medial thalamus.Corticotropin-releasing hormone-binding protein and stress: from invertebrates to humans.CRF₂ receptor-deficiency reduces recognition memory deficits and vulnerability to stress induced by cocaine withdrawal.Modulatory actions of corticotropin-releasing factor-binding protein.
P2860
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P2860
Displacement of corticotropin releasing factor from its binding protein as a possible treatment for Alzheimer's disease
description
1995 nî lūn-bûn
@nan
1995 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Displacement of corticotropin ...... atment for Alzheimer's disease
@ast
Displacement of corticotropin ...... atment for Alzheimer's disease
@en
Displacement of corticotropin ...... atment for Alzheimer's disease
@en-gb
Displacement of corticotropin ...... atment for Alzheimer's disease
@nl
type
label
Displacement of corticotropin ...... atment for Alzheimer's disease
@ast
Displacement of corticotropin ...... atment for Alzheimer's disease
@en
Displacement of corticotropin ...... atment for Alzheimer's disease
@en-gb
Displacement of corticotropin ...... atment for Alzheimer's disease
@nl
prefLabel
Displacement of corticotropin ...... atment for Alzheimer's disease
@ast
Displacement of corticotropin ...... atment for Alzheimer's disease
@en
Displacement of corticotropin ...... atment for Alzheimer's disease
@en-gb
Displacement of corticotropin ...... atment for Alzheimer's disease
@nl
P2093
P921
P356
P1433
P1476
Displacement of corticotropin ...... atment for Alzheimer's disease
@en
P2093
E B De Souza
J C Troncoso
S C Heinrichs
P2860
P2888
P356
10.1038/378284A0
P407
P577
1995-11-16T00:00:00Z
P6179
1005911186