about
The Werner syndrome protein is distinguished from the Bloom syndrome protein by its capacity to tightly bind diverse DNA structuresWerner SyndromeFunctional and physical interaction between WRN helicase and human replication protein AEpigenetic changes of DNA repair genes in cancerKu complex interacts with and stimulates the Werner proteinPotent inhibition of werner and bloom helicases by DNA minor groove binding drugsCharacterization of the human and mouse WRN 3'-->5' exonucleaseRegulation and localization of the Bloom syndrome protein in response to DNA damageA functional interaction of Ku with Werner exonuclease facilitates digestion of damaged DNADiverged nuclear localization of Werner helicase in human and mouse cellsp53 Modulates the exonuclease activity of Werner syndrome proteinThe Bloom's and Werner's syndrome proteins are DNA structure-specific helicasesWerner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activityPhysical and functional interaction of the Werner syndrome protein with poly-ADP ribosyl transferaseWRN helicase and FEN-1 form a complex upon replication arrest and together process branchmigrating DNA structures associated with the replication forkTelomere-binding protein TRF2 binds to and stimulates the Werner and Bloom syndrome helicasesIdentification and biochemical characterization of a Werner's syndrome protein complex with Ku70/80 and poly(ADP-ribose) polymerase-1Physical and functional mapping of the replication protein a interaction domain of the werner and bloom syndrome helicasesAsymmetry of DNA replication fork progression in Werner's syndromeThe human Werner syndrome protein stimulates repair of oxidative DNA base damage by the DNA glycosylase NEIL1Werner syndrome protein phosphorylation by abl tyrosine kinase regulates its activity and distributionNucleolar localization of the Werner syndrome protein in human cellsThe spectrum of WRN mutations in Werner syndrome patientsPhysical and functional interactions between Werner syndrome helicase and mismatch-repair initiation factorsCharacterization of the enzymatic activity of hChlR1, a novel human DNA helicaseRequirement for three novel protein complexes in the absence of the Sgs1 DNA helicase in Saccharomyces cerevisiaeAnalysis of the unwinding activity of the dimeric RECQ1 helicase in the presence of human replication protein Ap53-mediated apoptosis is attenuated in Werner syndrome cellsRoles of Werner syndrome protein in protection of genome integrityModel of human aging: recent findings on Werner's and Hutchinson-Gilford progeria syndromesDomain mapping of Escherichia coli RecQ defines the roles of conserved N- and C-terminal regions in the RecQ familyWerner protein recruits DNA polymerase delta to the nucleolusThe interaction site of Flap Endonuclease-1 with WRN helicase suggests a coordination of WRN and PCNANucleolin inhibits G4 oligonucleotide unwinding by Werner helicaseStructure of the human RECQ1 helicase reveals a putative strand-separation pinThe Saccharomyces cerevisiae Sgs1 helicase efficiently unwinds G-G paired DNAs.Mutations in homologous recombination genes rescue top3 slow growth in Saccharomyces cerevisiae.The MER3 DNA helicase catalyzes the unwinding of holliday junctions.Y'-Help1, a DNA helicase encoded by the yeast subtelomeric Y' element, is induced in survivors defective for telomerase.Role of SGS1 and SLX4 in maintaining rDNA structure in Saccharomyces cerevisiae.
P2860
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P2860
description
1997 nî lūn-bûn
@nan
1997 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
The Werner syndrome protein is a DNA helicase
@ast
The Werner syndrome protein is a DNA helicase
@en
The Werner syndrome protein is a DNA helicase
@en-gb
The Werner syndrome protein is a DNA helicase
@nl
type
label
The Werner syndrome protein is a DNA helicase
@ast
The Werner syndrome protein is a DNA helicase
@en
The Werner syndrome protein is a DNA helicase
@en-gb
The Werner syndrome protein is a DNA helicase
@nl
prefLabel
The Werner syndrome protein is a DNA helicase
@ast
The Werner syndrome protein is a DNA helicase
@en
The Werner syndrome protein is a DNA helicase
@en-gb
The Werner syndrome protein is a DNA helicase
@nl
P2093
P3181
P356
P1433
P1476
The Werner syndrome protein is a DNA helicase
@en
P2093
A S Kamath-Loeb
B L Sopher
G M Martin
P2888
P3181
P356
10.1038/NG0997-100
P407
P577
1997-09-01T00:00:00Z
P5875
P6179
1014232098