Asymmetry of DNA replication fork progression in Werner's syndrome
about
Physical and functional mapping of the replication protein a interaction domain of the werner and bloom syndrome helicasesPhysical and functional interactions between Werner syndrome helicase and mismatch-repair initiation factorsRoles of Werner syndrome protein in protection of genome integrityRoles of RECQ helicases in recombination based DNA repair, genomic stability and agingRecapitulation of Werner syndrome sensitivity to camptothecin by limited knockdown of the WRN helicase/exonucleaseWerner syndrome: Clinical features, pathogenesis and potential therapeutic interventionsInhibition of Werner syndrome helicase activity by benzo[a]pyrene diol epoxide adducts can be overcome by replication protein A.RecQ helicases: guardian angels of the DNA replication fork.Global regulation of genome duplication in eukaryotes: an overview from the epifluorescence microscope.Oxidative stress and antioxidant response in fibroblasts from Werner and atypical Werner syndromes.Molecular cooperation between the Werner syndrome protein and replication protein A in relation to replication fork blockage.The Drosophila Werner exonuclease participates in an exonuclease-independent response to replication stress.Delineation of WRN helicase function with EXO1 in the replicational stress responseAcetylation of Werner syndrome protein (WRN): relationships with DNA damage, DNA replication and DNA metabolic activities.Werner protein protects nonproliferating cells from oxidative DNA damageRoles of the Werner syndrome RecQ helicase in DNA replication.Nijmegen breakage syndrome fibroblasts expressing the C-terminal truncated NBN(p70) protein undergo p38/MK2-dependent premature senescence.The Werner and Bloom syndrome proteins help resolve replication blockage by converting (regressed) holliday junctions to functional replication forks.WRN helicase regulates the ATR-CHK1-induced S-phase checkpoint pathway in response to topoisomerase-I-DNA covalent complexes.Human RECQL5: guarding the crossroads of DNA replication and transcription and providing backup capabilityRMI1 promotes DNA replication fork progression and recovery from replication fork stressA novel Werner Syndrome mutation: pharmacological treatment by read-through of nonsense mutations and epigenetic therapiesAnalysis of the Xenopus Werner syndrome protein in DNA double-strand break repair.The role of DNA exonucleases in protecting genome stability and their impact on ageing.Distinct functions of human RECQ helicases WRN and BLM in replication fork recovery and progression after hydroxyurea-induced stalling.Mechanisms of RecQ helicases in pathways of DNA metabolism and maintenance of genomic stabilityIdentification and characterization of a Drosophila ortholog of WRN exonuclease that is required to maintain genome integrity.Replication stress induced site-specific phosphorylation targets WRN to the ubiquitin-proteasome pathwayFrom old organisms to new molecules: integrative biology and therapeutic targets in accelerated human ageing.Replication fork stalling in WRN-deficient cells is overcome by prompt activation of a MUS81-dependent pathway.Telomeres do the (un)twist: helicase actions at chromosome termini.CDK1 phosphorylates WRN at collapsed replication forks.The Werner Syndrome Helicase Coordinates Sequential Strand Displacement and FEN1-Mediated Flap Cleavage during Polymerase δ Elongation.Replication fork dynamics and the DNA damage response.Replication fork reversal in eukaryotes: from dead end to dynamic response.Class I Histone Deacetylase HDAC1 and WRN RECQ Helicase Contribute Additively to Protect Replication Forks upon Hydroxyurea-induced Arrest.Bloom's syndrome: Why not premature aging?: A comparison of the BLM and WRN helicases.Use of p38 MAPK Inhibitors for the Treatment of Werner Syndrome.The human WRN and BLM RecQ helicases differentially regulate cell proliferation and survival after chemotherapeutic DNA damage.Gram-scale synthesis of the p38α MAPK-inhibitor VX-745 for preclinical studies into Werner syndrome.
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P2860
Asymmetry of DNA replication fork progression in Werner's syndrome
description
2002 nî lūn-bûn
@nan
2002 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
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2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
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name
Asymmetry of DNA replication fork progression in Werner's syndrome
@ast
Asymmetry of DNA replication fork progression in Werner's syndrome
@en
Asymmetry of DNA replication fork progression in Werner's syndrome
@en-gb
Asymmetry of DNA replication fork progression in Werner's syndrome
@nl
type
label
Asymmetry of DNA replication fork progression in Werner's syndrome
@ast
Asymmetry of DNA replication fork progression in Werner's syndrome
@en
Asymmetry of DNA replication fork progression in Werner's syndrome
@en-gb
Asymmetry of DNA replication fork progression in Werner's syndrome
@nl
prefLabel
Asymmetry of DNA replication fork progression in Werner's syndrome
@ast
Asymmetry of DNA replication fork progression in Werner's syndrome
@en
Asymmetry of DNA replication fork progression in Werner's syndrome
@en-gb
Asymmetry of DNA replication fork progression in Werner's syndrome
@nl
P2860
P3181
P1433
P1476
Asymmetry of DNA replication fork progression in Werner's syndrome
@en
P2093
Ana M Rodríguez-López
Dean A Jackson
P2860
P3181
P356
10.1046/J.1474-9728.2002.00002.X
P407
P577
2002-10-01T00:00:00Z