A Grb2-associated docking protein in EGF- and insulin-receptor signalling
about
Molecular basis of signaling specificity of insulin and IGF receptors: neglected corners and recent advancesFunction, regulation and pathological roles of the Gab/DOS docking proteinsMolecular cloning of a docking protein, BRDG1, that acts downstream of the Tec tyrosine kinasePhosphotyrosines 627 and 659 of Gab1 constitute a bisphosphoryl tyrosine-based activation motif (BTAM) conferring binding and activation of SHP2Co-clustering of Fcgamma and B cell receptors induces dephosphorylation of the Grb2-associated binder 1 docking proteinThe major vault protein is a novel substrate for the tyrosine phosphatase SHP-2 and scaffold protein in epidermal growth factor signalingEnhanced prediction of Src homology 2 (SH2) domain binding potentials using a fluorescence polarization-derived c-Met, c-Kit, ErbB, and androgen receptor interactomeThe molecular scaffold Gab2 is a crucial component of RANK signaling and osteoclastogenesisIdentification of 14-3-3zeta as an EGF receptor interacting proteinRoles of Gab1 and SHP2 in paxillin tyrosine dephosphorylation and Src activation in response to epidermal growth factorDistinct domains in the SHP-2 phosphatase differentially regulate epidermal growth factor receptor/NF-kappaB activation through Gab1 in glioblastoma cellsCloning of a novel T-cell protein FYB that binds FYN and SH2-domain-containing leukocyte protein 76 and modulates interleukin 2 productionA novel role for Gab1 and SHP2 in epidermal growth factor-induced Ras activationActivation of HER4 by heparin-binding EGF-like growth factor stimulates chemotaxis but not proliferationRoles of the complex formation of SHPS-1 with SHP-2 in insulin-stimulated mitogen-activated protein kinase activationA novel, multifuntional c-Cbl binding protein in insulin receptor signaling in 3T3-L1 adipocytesErbB-1 and ErbB-2 acquire distinct signaling properties dependent upon their dimerization partner.Principles of interleukin (IL)-6-type cytokine signalling and its regulationIdentification and analysis of PH domain-containing targets of phosphatidylinositol 3-kinase using a novel in vivo assay in yeast.Tyrosine phosphorylation of p62(Dok) induced by cell adhesion and insulin: possible role in cell migrationPKB-mediated negative feedback tightly regulates mitogenic signalling via Gab2.Induced expression and association of the Mona/Gads adapter and Gab3 scaffolding protein during monocyte/macrophage differentiation.Association of insulin receptor substrate proteins with Bcl-2 and their effects on its phosphorylation and antiapoptotic functionFRS2 proteins recruit intracellular signaling pathways by binding to diverse targets on fibroblast growth factor and nerve growth factor receptorsCharacterization of a novel member of the DOK family that binds and modulates Abl signalingThe Gab1 PH domain is required for localization of Gab1 at sites of cell-cell contact and epithelial morphogenesis downstream from the met receptor tyrosine kinaseRegPhos: a system to explore the protein kinase-substrate phosphorylation network in humansStimulation of phosphatidylinositol 3-kinase by fibroblast growth factor receptors is mediated by coordinated recruitment of multiple docking proteinsCritical role for the docking-protein FRS2 alpha in FGF receptor-mediated signal transduction pathwaysGrb2-associated binding (Gab) proteins in hematopoietic and immune cell biologyGrb2-associated binder-1 mediates phosphatidylinositol 3-kinase activation and the promotion of cell survival by nerve growth factorEssential role of Gab1 for signaling by the c-Met receptor in vivoThe docking protein Gab1 is the primary mediator of EGF-stimulated activation of the PI-3K/Akt cell survival pathwayStructure and function of Gab2 and its role in cancer (Review)Molecular Basis of Gain-of-Function LEOPARD Syndrome-Associated SHP2 MutationsTyrosyl phosphorylation of Shp2 is required for normal ERK activation in response to some, but not all, growth factorsA deubiquitinating enzyme UBPY interacts with the Src homology 3 domain of Hrs-binding protein via a novel binding motif PX(V/I)(D/N)RXXKPGab2, a new pleckstrin homology domain-containing adapter protein, acts to uncouple signaling from ERK kinase to Elk-1Sustained recruitment of phospholipase C-gamma to Gab1 is required for HGF-induced branching tubulogenesisMet receptor tyrosine kinase: enhanced signaling through adapter proteins
P2860
Q21131281-49B5FF2F-C427-405A-8066-350651F4F909Q21245511-5849E08F-7558-40F9-AC5D-E0E3E0DC29ABQ22010641-0FFD7A3F-122C-49B2-86B6-4144901BDEBEQ24291169-AC6E3CD1-F7B4-4B37-BF65-7883F85A6B5CQ24291446-61D8D381-8AD1-4480-B7BB-B5BBFD9A1262Q24292713-998A243C-4AB0-4FA7-A6DD-A8DF6BDCEE9DQ24294625-4B023BBA-0227-42B9-89E1-E6DAACF90C3EQ24297505-BFDC5BF6-C983-426E-B9D0-AAE7CDCE2ABEQ24298129-36541BD0-7947-4FA9-89B1-BF4CCA8AE148Q24301556-E1BF1F17-2AB1-4352-9356-C67629609DF4Q24303794-1E34A485-8E24-4317-B767-09BEACB50CE6Q24314382-6D9E5C7C-E123-4C6F-A733-734A450417E2Q24318482-B008D2A9-AF53-4F9A-ABCC-9F31FABBA6F0Q24318527-858BFF13-210F-4847-A007-FDB7CFC4C26EQ24322598-862CEE36-7A85-43CA-B157-ED96973FF6B2Q24324468-7B7595B6-839F-4D35-BDAF-03BDA45F400FQ24522643-0B907B04-EDAF-4F94-A66B-35F9C9305735Q24530173-C8B44259-A2E5-446E-97D0-AD6BD16B9581Q24533315-E067DD18-8F9B-4B6B-B0A0-EF65810C527DQ24534026-3185640C-DEFD-4926-ACCA-0CED17A5A55BQ24536142-66E9D69E-CA8E-40CD-9C52-34B1A533A031Q24537376-71103C8D-B14C-4C04-974E-B7F57D49CC88Q24548364-24CDEFB8-3167-473F-9E71-246E521FA4FFQ24554326-A32980E4-6950-465C-96EA-29A8C2895F25Q24554382-6430571E-04C4-4C56-A1FC-EA2834E5CF0CQ24554529-A3EA826C-BA2C-453F-9A6F-AC11F89E4453Q24607576-EC99C7E1-6DD6-44AE-9C1E-F679081D70F4Q24629903-7D5E2A0C-4FFF-4215-8D0F-E352695BA279Q24630500-F4C3623B-07DF-41A4-BA8A-71C75AECE62CQ24631296-D625699F-3DC2-4203-9A6C-74355EEEBB08Q24648537-B764181F-4ABB-48F6-846D-CD133D47ECE1Q24685688-29FBBB35-F2F4-4853-B991-DD8AA0D32E77Q24799816-2327EEF5-6EA6-4348-8073-A75A45099123Q26825507-A0854AEC-674E-467C-A7FE-4D676B5754F6Q27684353-39C2AB8E-7B2E-415E-AE68-CB024CA81FD8Q28118868-BCB3E696-BEF3-4F66-965D-75D972363EC7Q28138440-80D013DD-3821-4DC1-AC79-3DC0472F8D0BQ28138626-56BCFF5B-E960-42CF-AB6C-EB8723E77429Q28139783-25E18E6B-BBDA-428A-B95C-76A73BA8CCFBQ28140219-B2F167A2-53DC-4994-BFFF-0A9090B9FA1F
P2860
A Grb2-associated docking protein in EGF- and insulin-receptor signalling
description
1996 nî lūn-bûn
@nan
1996 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
A Grb2-associated docking protein in EGF- and insulin-receptor signalling
@ast
A Grb2-associated docking protein in EGF- and insulin-receptor signalling
@en
A Grb2-associated docking protein in EGF- and insulin-receptor signalling
@en-gb
A Grb2-associated docking protein in EGF- and insulin-receptor signalling
@nl
type
label
A Grb2-associated docking protein in EGF- and insulin-receptor signalling
@ast
A Grb2-associated docking protein in EGF- and insulin-receptor signalling
@en
A Grb2-associated docking protein in EGF- and insulin-receptor signalling
@en-gb
A Grb2-associated docking protein in EGF- and insulin-receptor signalling
@nl
prefLabel
A Grb2-associated docking protein in EGF- and insulin-receptor signalling
@ast
A Grb2-associated docking protein in EGF- and insulin-receptor signalling
@en
A Grb2-associated docking protein in EGF- and insulin-receptor signalling
@en-gb
A Grb2-associated docking protein in EGF- and insulin-receptor signalling
@nl
P2093
P921
P3181
P356
P1433
P1476
A Grb2-associated docking protein in EGF- and insulin-receptor signalling
@en
P2093
A K Godwin
D K Moscatello
M Holgado-Madruga
P2888
P3181
P356
10.1038/379560A0
P407
P577
1996-02-08T00:00:00Z
P5875
P6179
1043414343