Tiki1 is required for head formation via Wnt cleavage-oxidation and inactivation
about
Expression and evolution of the Tiki1 and Tiki2 genes in vertebratesNotum deacylates Wnt proteins to suppress signalling activitymicroRNA regulation of Wnt signaling pathways in development and diseaseBridging the gap: heparan sulfate and Scube2 assemble Sonic hedgehog release complexes at the surface of producing cells.Dynamic association with donor cell filopodia and lipid-modification are essential features of Wnt8a during patterning of the zebrafish neuroectodermEnterococcal Sex Pheromones: Evolutionary Pathways to Complex, Two-Signal SystemsNotum is required for neural and head induction via Wnt deacylation, oxidation, and inactivationWnt proteins.Characterization of Tiki, a New Family of Wnt-specific Metalloproteases.Disulfide bond requirements for active Wnt ligands.Generation of multi-gene knockout rabbits using the Cas9/gRNA system.Use of a molecular genetic platform technology to produce human Wnt proteins reveals distinct local and distal signaling abilitiesIsoquercitrin suppresses colon cancer cell growth in vitro by targeting the Wnt/β-catenin signaling pathwayCorrelated alterations in genome organization, histone methylation, and DNA-lamin A/C interactions in Hutchinson-Gilford progeria syndrome.Secreted and transmembrane wnt inhibitors and activators.TIKI2 is upregulated and plays an oncogenic role in renal cell carcinoma.The way Wnt works: components and mechanism.Specification of anteroposterior axis by combinatorial signaling during Xenopus development.Vertebrate Axial Patterning: From Egg to Asymmetry.TIKI2 suppresses growth of osteosarcoma by targeting Wnt/β-catenin pathway.WNT signalling events near the cell membrane and their pharmacological targeting for the treatment of cancer.An emerging role of Sonic hedgehog shedding as a modulator of heparan sulfate interactionsWnt Signaling in Ewing Sarcoma, Osteosarcoma, and Malignant Peripheral Nerve Sheath Tumors.Celebrating 30 years of Wnt signaling.Genome-wide analysis of dorsal and ventral transcriptomes of the Xenopus laevis gastrula.Structural architecture and functional evolution of WntsThe TIKI/TraB/PrgY family: a common protease fold for cell signaling from bacteria to metazoa?Endocytosis of Fgf8 is a double-stage process and regulates spreading and signaling.Crystal structure of R-spondin 2 in complex with the ectodomains of its receptors LGR5 and ZNRF3.Taking a bite out of Wnts.Wnt/β-catenin signaling during early vertebrate neural development.Probing Wnt Receptor Turnover: A Critical Regulatory Point of Wnt Pathway.Methods for Studying Wnt Protein Modifications/Inactivations by Extracellular Enzymes, Tiki and Notum.Taking the Occam's Razor Approach to Hedgehog Lipidation and Its Role in Development.Assembly of protein complexes restricts diffusion of Wnt3a proteinsBighead is a Wnt antagonist secreted by the Spemann organizer that promotes Lrp6 endocytosis
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P2860
Tiki1 is required for head formation via Wnt cleavage-oxidation and inactivation
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Tiki1 is required for head formation via Wnt cleavage-oxidation and inactivation
@ast
Tiki1 is required for head formation via Wnt cleavage-oxidation and inactivation
@en
Tiki1 is required for head formation via Wnt cleavage-oxidation and inactivation
@en-gb
Tiki1 is required for head formation via Wnt cleavage-oxidation and inactivation
@nl
type
label
Tiki1 is required for head formation via Wnt cleavage-oxidation and inactivation
@ast
Tiki1 is required for head formation via Wnt cleavage-oxidation and inactivation
@en
Tiki1 is required for head formation via Wnt cleavage-oxidation and inactivation
@en-gb
Tiki1 is required for head formation via Wnt cleavage-oxidation and inactivation
@nl
prefLabel
Tiki1 is required for head formation via Wnt cleavage-oxidation and inactivation
@ast
Tiki1 is required for head formation via Wnt cleavage-oxidation and inactivation
@en
Tiki1 is required for head formation via Wnt cleavage-oxidation and inactivation
@en-gb
Tiki1 is required for head formation via Wnt cleavage-oxidation and inactivation
@nl
P2093
P2860
P921
P3181
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P1476
Tiki1 is required for head formation via Wnt cleavage-oxidation and inactivation
@en
P2093
Bryan T MacDonald
Chika Yokota
Hanno Steen
Howard C Hang
Jose Garcia Abreu
Karla Loureiro Almeida Coburn
Mingzi M Zhang
Qi-Zhuang Ye
Sasha Singh
Seong-Moon Cheong
P2860
P304
P3181
P356
10.1016/J.CELL.2012.04.039
P407
P577
2012-06-22T00:00:00Z