Use of a molecular genetic platform technology to produce human Wnt proteins reveals distinct local and distal signaling abilities

Use of a molecular genetic platform technology to produce human Wnt proteins reveals distinct local and distal signaling abilities

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http://www.wikidata.org/entity/Q34629577
A versatile platform to analyze low-affinity and transient protein-protein interactions in living cells in real timeWNT5A encodes two isoforms with distinct functions in cancersDisulfide bond requirements for active Wnt ligands.A rare human syndrome provides genetic evidence that WNT signaling is required for reprogramming of fibroblasts to induced pluripotent stem cellsOsteoblast-derived WNT16 represses osteoclastogenesis and prevents cortical bone fragility fracturesParacrine Wnt signaling both promotes and inhibits human breast tumor growth.Active and water-soluble form of lipidated Wnt protein is maintained by a serum glycoprotein afamin/α-albumin.A WNT protein therapeutic improves the bone-forming capacity of autografts from aged animals.Canonical Wnt inhibitors ameliorate cystogenesis in a mouse ortholog of human ADPKD.
P2860

Use of a molecular genetic platform technology to produce human Wnt proteins reveals distinct local and distal signaling abilities

Item
http://www.wikidata.org/entity/Q34629577
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2013 թուականի Մարտին հրատարակուած գիտական յօդուած
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2013 թվականի մարտին հրատարակված գիտական հոդված
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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Use of a molecular genetic pla ...... and distal signaling abilities
@ast
Use of a molecular genetic pla ...... and distal signaling abilities
@en
Use of a molecular genetic pla ...... and distal signaling abilities
@nl
type
label
Use of a molecular genetic pla ...... and distal signaling abilities
@ast
Use of a molecular genetic pla ...... and distal signaling abilities
@en
Use of a molecular genetic pla ...... and distal signaling abilities
@nl
prefLabel
Use of a molecular genetic pla ...... and distal signaling abilities
@ast
Use of a molecular genetic pla ...... and distal signaling abilities
@en
Use of a molecular genetic pla ...... and distal signaling abilities
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
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P577
P5875
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P932
P356
P1433
P1476
Use of a molecular genetic pla ...... and distal signaling abilities
@en
P2093
P2860
P304
P31
P356
10.1371/JOURNAL.PONE.0058395
P407
P433
P478
P577
P5875
P698
P932