Mona, a novel hematopoietic-specific adaptor interacting with the macrophage colony-stimulating factor receptor, is implicated in monocyte/macrophage development.
about
Association of Grb2, Gads, and phospholipase C-gamma 1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell angigen receptor-mediated signalingInduced expression and association of the Mona/Gads adapter and Gab3 scaffolding protein during monocyte/macrophage differentiation.Identification of a phospholipase C-gamma1 (PLC-gamma1) SH3 domain-binding site in SLP-76 required for T-cell receptor-mediated activation of PLC-gamma1 and NFATInhibition of ErbB-2 mitogenic and transforming activity by RALT, a mitogen-induced signal transducer which binds to the ErbB-2 kinase domainGrf40, A novel Grb2 family member, is involved in T cell signaling through interaction with SLP-76 and LATGrpL, a Grb2-related adaptor protein, interacts with SLP-76 to regulate nuclear factor of activated T cell activationFlt3+ macrophage precursors commit sequentially to osteoclasts, dendritic cells and microglia.Structural basis for SH3 domain-mediated high-affinity binding between Mona/Gads and SLP-76Heterocomplex formation between metastasis-related protein S100A4 (Mts1) and S100A1 as revealed by the yeast two-hybrid systemThe inositol 5'-phosphatase SHIP-1 and the Src kinase Lyn negatively regulate macrophage colony-stimulating factor-induced Akt activityc-Cbl associates directly with the C-terminal tail of the receptor for the macrophage colony-stimulating factor, c-Fms, and down-modulates this receptor but not the viral oncogene v-FmsSuppressor of cytokine signaling 1 interacts with the macrophage colony-stimulating factor receptor and negatively regulates its proliferation signalLAT, the linker for activation of T cells: a bridge between T cell-specific and general signaling pathwaysLeukocyte-specific adaptor protein Grap2 interacts with hematopoietic progenitor kinase 1 (HPK1) to activate JNK signaling pathway in T lymphocytesThe C-terminal SH3 domain of the adapter protein Grb2 binds with high affinity to sequences in Gab1 and SLP-76 which lack the SH3-typical P-x-x-P core motifThe SH2 domain-containing proteins in 21 species establish the provenance and scope of phosphotyrosine signaling in eukaryotesFiz1, a novel zinc finger protein interacting with the receptor tyrosine kinase Flt3SHP-1 regulation of p62(DOK) tyrosine phosphorylation in macrophagesExpression of GADS enhances FLT3-induced mitogenic signaling.Importance of CH/π hydrogen bonds in recognition of the core motif in proline-recognition domains: an ab initio fragment molecular orbital study.Intracellular protein interaction mapping with FRET hybrids.Grap-2, a novel RET binding protein, is involved in RET mitogenic signaling.The role of Gads in hematopoietic cell signalling.CD95/Fas induces cleavage of the GrpL/Gads adaptor and desensitization of antigen receptor signaling.Expression of Mona (monocytic adapter) in myeloid progenitor cells results in increased and prolonged MAP kinase activation upon macrophage colony-stimulating factor stimulation.Early events in M-CSF receptor signaling.Sin: good or bad? A T lymphocyte perspective.The role of the adapter molecule SLP-76 in platelet function.Signalling scaffolds and adaptors in T-cell immunity.Phorbol 12-myristate 13-acetate-induced release of the colony-stimulating factor 1 receptor cytoplasmic domain into the cytosol involves two separate cleavage eventsT lymphocyte activation--an inside overview.Gab3-deficient mice exhibit normal development and hematopoiesis and are immunocompetent.Evidence for the requirement of ITAM domains but not SLP-76/Gads interaction for integrin signaling in hematopoietic cells.Gads regulates the expansion phase of CD8+ T cell-mediated immunity.Agrin is required for survival and function of monocytic cellsRecruitment of SLP-76 to the membrane and glycolipid-enriched membrane microdomains replaces the requirement for linker for activation of T cells in T cell receptor signalingSrc-like adaptor protein regulates osteoclast generation and survival.Gads-deficient thymocytes are blocked at the transitional single positive CD4+ stage.CSF-1 signaling in macrophages: pleiotrophy through phosphotyrosine-based signaling pathways.Gab adapter proteins as therapeutic targets for hematologic disease.
P2860
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P2860
Mona, a novel hematopoietic-specific adaptor interacting with the macrophage colony-stimulating factor receptor, is implicated in monocyte/macrophage development.
description
1998 nî lūn-bûn
@nan
1998 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
name
Mona, a novel hematopoietic-sp ...... onocyte/macrophage development
@nl
Mona, a novel hematopoietic-sp ...... nocyte/macrophage development.
@ast
Mona, a novel hematopoietic-sp ...... nocyte/macrophage development.
@en
type
label
Mona, a novel hematopoietic-sp ...... onocyte/macrophage development
@nl
Mona, a novel hematopoietic-sp ...... nocyte/macrophage development.
@ast
Mona, a novel hematopoietic-sp ...... nocyte/macrophage development.
@en
prefLabel
Mona, a novel hematopoietic-sp ...... onocyte/macrophage development
@nl
Mona, a novel hematopoietic-sp ...... nocyte/macrophage development.
@ast
Mona, a novel hematopoietic-sp ...... nocyte/macrophage development.
@en
P2093
P2860
P356
P1433
P1476
Mona, a novel hematopoietic-sp ...... nocyte/macrophage development.
@en
P2093
Blanchet JP
Bourette RP
Mouchiroud G
Rohrschneider LR
P2860
P304
P356
10.1093/EMBOJ/17.24.7273
P407
P577
1998-12-01T00:00:00Z