Galpha 12 activates Rho GTPase through tyrosine-phosphorylated leukemia-associated RhoGEF.
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Physical and functional interactions of the lysophosphatidic acid receptors with PDZ domain-containing Rho guanine nucleotide exchange factors (RhoGEFs)Mutation of an N-terminal acidic-rich region of p115-RhoGEF dissociates alpha13 binding and alpha13-promoted plasma membrane recruitmentIdentification of a novel sequence in PDZ-RhoGEF that mediates interaction with the actin cytoskeletonA comprehensive pathway map of epidermal growth factor receptor signalingMAGI-3 regulates LPA-induced activation of Erk and RhoAExpansion of signal transduction by G proteins. The second 15 years or so: from 3 to 16 alpha subunits plus betagamma dimersThe GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunitsPhosphorylation-mediated regulation of GEFs for RhoAIdentification of Critical Residues in G 13 for Stimulation of p115RhoGEF Activity and the Structure of the G 13-p115RhoGEF Regulator of G Protein Signaling Homology (RH) Domain ComplexStructural Determinants of RGS-RhoGEF Signaling Critical to Entamoeba histolytica PathogenesisDirect interaction of p21-activated kinase 4 with PDZ-RhoGEF, a G protein-linked Rho guanine exchange factorThrombin and lysophosphatidic acid receptors utilize distinct rhoGEFs in prostate cancer cellsStructural determinants of RhoA binding and nucleotide exchange in leukemia-associated Rho guanine-nucleotide exchange factorPhospholipase C, Ca2+, and calmodulin signaling are required for 5-HT2A receptor-mediated transamidation of Rac1 by transglutaminaseThe A-kinase anchoring protein (AKAP)-Lbc-signaling complex mediates alpha1 adrenergic receptor-induced cardiomyocyte hypertrophyOn the mechanism of autoinhibition of the RhoA-specific nucleotide exchange factor PDZRhoGEF.A new approach to producing functional G alpha subunits yields the activated and deactivated structures of G alpha(12/13) proteinsThe P2Y2 nucleotide receptor requires interaction with alpha v integrins to access and activate G12.RhoA GTPase inhibition organizes contraction during epithelial morphogenesis.Structure and function of heterotrimeric G protein-regulated Rho guanine nucleotide exchange factors.Local delivery of novel MRTF/SRF inhibitors prevents scar tissue formation in a preclinical model of fibrosis.Interaction between src family kinases and rho-kinase in agonist-induced Ca2+-sensitization of rat pulmonary artery.The Ras-related protein, Rap1A, mediates thrombin-stimulated, integrin-dependent glioblastoma cell proliferation and tumor growthRegulated localization is sufficient for hormonal control of regulator of G protein signaling homology Rho guanine nucleotide exchange factors (RH-RhoGEFs).The neurotrophin-3 receptor TrkC directly phosphorylates and activates the nucleotide exchange factor Dbs to enhance Schwann cell migrationThe function of integrin-linked kinase in normal and activated stellate cells: implications for fibrogenesis in wound healingSrc kinase regulates the activation of a novel FGD-1-related Cdc42 guanine nucleotide exchange factor in the signaling pathway from the endothelin A receptor to JNK.Identification and molecular characterization of the G alpha12-Rho guanine nucleotide exchange factor pathway in Caenorhabditis elegansO-GlcNAcylation: a novel pathway contributing to the effects of endothelin in the vasculature.Modulation of a GEF switch: autoinhibition of the intrinsic guanine nucleotide exchange activity of p115-RhoGEFp190RhoGEF (Rgnef) promotes colon carcinoma tumor progression via interaction with focal adhesion kinase.Galpha encoding gene family of the malaria vector mosquito Anopheles gambiae: expression analysis and immunolocalization of AGalphaq and AGalphao in female antennaeThe leukemia-associated Rho guanine nucleotide exchange factor LARG is required for efficient replication stress signaling.Signalling mechanisms of RhoGTPase regulation by the heterotrimeric G proteins G12 and G13Progress in methodology. Improved reporter gene assays used to identify ligands acting on orphan seven-transmembrane receptors.Oxidative species increase arginase activity in endothelial cells through the RhoA/Rho kinase pathway.Gastrin-stimulated Gα13 Activation of Rgnef Protein (ArhGEF28) in DLD-1 Colon Carcinoma Cells.A finer tuning of G-protein signaling through regulated control of RGS proteins.Activation of p115-RhoGEF requires direct association of Gα13 and the Dbl homology domainThe interaction of Gα13 with integrin β1 mediates cell migration by dynamic regulation of RhoA
P2860
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P2860
Galpha 12 activates Rho GTPase through tyrosine-phosphorylated leukemia-associated RhoGEF.
description
2003 nî lūn-bûn
@nan
2003 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Galpha 12 activates Rho GTPase through tyrosine-phosphorylated leukemia-associated RhoGEF
@nl
Galpha 12 activates Rho GTPase ...... ed leukemia-associated RhoGEF.
@ast
Galpha 12 activates Rho GTPase ...... ed leukemia-associated RhoGEF.
@en
type
label
Galpha 12 activates Rho GTPase through tyrosine-phosphorylated leukemia-associated RhoGEF
@nl
Galpha 12 activates Rho GTPase ...... ed leukemia-associated RhoGEF.
@ast
Galpha 12 activates Rho GTPase ...... ed leukemia-associated RhoGEF.
@en
prefLabel
Galpha 12 activates Rho GTPase through tyrosine-phosphorylated leukemia-associated RhoGEF
@nl
Galpha 12 activates Rho GTPase ...... ed leukemia-associated RhoGEF.
@ast
Galpha 12 activates Rho GTPase ...... ed leukemia-associated RhoGEF.
@en
P2093
P2860
P356
P1476
Galpha 12 activates Rho GTPase ...... ed leukemia-associated RhoGEF.
@en
P2093
Hiroyuki Mano
Nobuchika Suzuki
Susumu Nakamura
Tohru Kozasa
P2860
P304
P356
10.1073/PNAS.0234057100
P407
P577
2003-01-06T00:00:00Z