The structure of a protein primer-polymerase complex in the initiation of genome replication.
about
An RNA virus hijacks an incognito function of a DNA repair enzymeNMR solution structure of poliovirus uridylyated peptide linked to the genome (VPgpU)Structures of the compact helical core domains of feline calicivirus and murine norovirus VPg proteinsPicornavirus genome replication: roles of precursor proteins and rate-limiting steps in oriI-dependent VPg uridylylationThe crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase in complex with its protein primer VPg confirms the existence of a second VPg binding site on Picornaviridae polymerasesHuman rhinovirus type 14 gain-of-function mutants for oriI utilization define residues of 3C(D) and 3Dpol that contribute to assembly and stability of the picornavirus VPg uridylylation complexBiological function of Foot-and-mouth disease virus non-structural proteins and non-coding elementsRNA-Dependent RNA Polymerases of Picornaviruses: From the Structure to Regulatory MechanismsCommon and unique features of viral RNA-dependent polymerasesCrystal Structure of the Dengue Virus RNA-Dependent RNA Polymerase Catalytic Domain at 1.85-Angstrom ResolutionDe Novo Initiation of RNA Synthesis by the Arterivirus RNA-Dependent RNA PolymeraseStructure-function relationships among RNA-dependent RNA polymerasesCrystal Structure of Poliovirus 3CD Protein: Virally Encoded Protease and Precursor to the RNA-Dependent RNA PolymeraseSequential structures provide insights into the fidelity of RNA replicationCrystal Structure of Enterovirus 71 RNA-Dependent RNA Polymerase Complexed with Its Protein Primer VPg: Implication for a trans Mechanism of VPg UridylylationStructures of coxsackievirus, rhinovirus, and poliovirus polymerase elongation complexes solved by engineering RNA mediated crystal contactsDistinct Conformations of a Putative Translocation Element in Poliovirus PolymeraseThe Crystal Structure of a Cardiovirus RNA-Dependent RNA Polymerase Reveals an Unusual Conformation of the Polymerase Active SiteInhibitors of foot and mouth disease virus targeting a novel pocket of the RNA-dependent RNA polymeraseA Structural Overview of RNA-Dependent RNA Polymerases from the Flaviviridae FamilyDeletion mutants of VPg reveal new cytopathology determinants in a picornavirus.RNA virus replication complexesRepeated exposure to 5D9, an inhibitor of 3D polymerase, effectively limits the replication of foot-and-mouth disease virus in host cells.Characterization of protein-protein interactions critical for poliovirus replication: analysis of 3AB and VPg binding to the RNA-dependent RNA polymerase.Structure-function relationships of the viral RNA-dependent RNA polymerase: fidelity, replication speed, and initiation mechanism determined by a residue in the ribose-binding pocketEnterovirus 71 VPg uridylation uses a two-molecular mechanism of 3D polymerase.Ribavirin-resistant mutants of human enterovirus 71 express a high replication fidelity phenotype during growth in cell cultureIntrinsic disorder in Viral Proteins Genome-Linked: experimental and predictive analyses.Cis-active RNA elements (CREs) and picornavirus RNA replicationVaccine-derived mutation in motif D of poliovirus RNA-dependent RNA polymerase lowers nucleotide incorporation fidelity.Self-guanylylation of birnavirus VP1 does not require an intact polymerase activity site.Expanding knowledge of P3 proteins in the poliovirus lifecycle.5-fluorouracil in lethal mutagenesis of foot-and-mouth disease virus.Viral polymerases.RNA synthetic mechanisms employed by diverse families of RNA viruses.Three-dimensional structure of foot-and-mouth disease virus and its biological functions.Viruses and viral proteins.Picornavirus genome replication. Identification of the surface of the poliovirus (PV) 3C dimer that interacts with PV 3Dpol during VPg uridylylation and construction of a structural model for the PV 3C2-3Dpol complexInitiation of protein-primed picornavirus RNA synthesis.Role of RNA structure and RNA binding activity of foot-and-mouth disease virus 3C protein in VPg uridylylation and virus replication
P2860
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P2860
The structure of a protein primer-polymerase complex in the initiation of genome replication.
description
2006 nî lūn-bûn
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2006 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի փետրվարին հրատարակված գիտական հոդված
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2006年の論文
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2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
The structure of a protein pri ...... itiation of genome replication
@nl
The structure of a protein pri ...... tiation of genome replication.
@ast
The structure of a protein pri ...... tiation of genome replication.
@en
type
label
The structure of a protein pri ...... itiation of genome replication
@nl
The structure of a protein pri ...... tiation of genome replication.
@ast
The structure of a protein pri ...... tiation of genome replication.
@en
altLabel
The structure of a protein pri ...... itiation of genome replication
@en
prefLabel
The structure of a protein pri ...... itiation of genome replication
@nl
The structure of a protein pri ...... tiation of genome replication.
@ast
The structure of a protein pri ...... tiation of genome replication.
@en
P2093
P2860
P50
P3181
P356
P1433
P1476
The structure of a protein pri ...... tiation of genome replication.
@en
P2093
Cristina Escarmís
Cristina Ferrer-Orta
Rosa Pérez-Luque
Rubén Agudo
P2860
P304
P3181
P356
10.1038/SJ.EMBOJ.7600971
P407
P577
2006-02-02T00:00:00Z