Oligomerization of DH domain is essential for Dbl-induced transformation
about
Homo-oligomerization of ALS2 through its unique carboxyl-terminal regions is essential for the ALS2-associated Rab5 guanine nucleotide exchange activity and its regulatory function on endosome traffickingNm23-H1 modulates the activity of the guanine exchange factor Dbl-1The tandem BRCT domains of Ect2 are required for both negative and positive regulation of Ect2 in cytokinesisThe Minimal Autoinhibited Unit of the Guanine Nucleotide Exchange Factor IntersectinRegulation of proto-Dbl by intracellular membrane targeting and protein stabilityOverexpression of the Rho-guanine nucleotide exchange factor ECT2 inhibits nuclear translocation of nuclear receptor CAR in the mouse liverDefective dendrite elongation but normal fertility in mice lacking the Rho-like GTPase activator Dbl.The novel Cdc42 guanine nucleotide exchange factor, zizimin1, dimerizes via the Cdc42-binding CZH2 domain.Phosphorylation of MyoGEF on Thr-574 by Plk1 promotes MyoGEF localization to the central spindle.Leucine zipper-mediated homo-oligomerization regulates the Rho-GEF activity of AKAP-Lbc.Autoinhibition mechanism of proto-Dbl.The Sec14 homology domain regulates the cellular distribution and transforming activity of the Rho-specific guanine nucleotide exchange factor Dbs.Dimerization of DOCK2 is essential for DOCK2-mediated Rac activation and lymphocyte migration.Intramolecular interactions between the Dbl homology (DH) domain and the carboxyl-terminal region of myosin II-interacting guanine nucleotide exchange factor (MyoGEF) act as an autoinhibitory mechanism for the regulation of MyoGEF functions.N-terminal Dbl domain of the RhoGEF, Kalirin.Lsc activity is controlled by oligomerization and regulates integrin adhesion.Modulation of Rho guanine exchange factor Lfc activity by protein kinase A-mediated phosphorylation.Pleiotropic defects in TCR signaling in a Vav-1-null Jurkat T-cell line.GFScan: a gene family search tool at genomic DNA level.New insights into the dimerization of small GTPase Rac/ROP guanine nucleotide exchange factors in riceThe Dbs PH domain contributes independently to membrane targeting and regulation of guanine nucleotide-exchange activity.The Rho guanine nucleotide exchange factor Lsc homo-oligomerizes and is negatively regulated through domains in its carboxyl terminus that are absent in novel splenic isoforms.Requirement for PAK4 in the anchorage-independent growth of human cancer cell lines.Oligomerization regulates the localization of Cdc24, the Cdc42 activator in Saccharomyces cerevisiae.
P2860
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P2860
Oligomerization of DH domain is essential for Dbl-induced transformation
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2001 nî lūn-bûn
@nan
2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Oligomerization of DH domain is essential for Dbl-induced transformation
@ast
Oligomerization of DH domain is essential for Dbl-induced transformation
@en
Oligomerization of DH domain is essential for Dbl-induced transformation
@nl
type
label
Oligomerization of DH domain is essential for Dbl-induced transformation
@ast
Oligomerization of DH domain is essential for Dbl-induced transformation
@en
Oligomerization of DH domain is essential for Dbl-induced transformation
@nl
prefLabel
Oligomerization of DH domain is essential for Dbl-induced transformation
@ast
Oligomerization of DH domain is essential for Dbl-induced transformation
@en
Oligomerization of DH domain is essential for Dbl-induced transformation
@nl
P2093
P2860
P1476
Oligomerization of DH domain is essential for Dbl-induced transformation
@en
P2093
P2860
P304
P356
10.1128/MCB.21.2.425-437.2001
P407
P577
2001-01-01T00:00:00Z