Molecular cloning and expression of human leukotriene-C4 synthase
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Identification and characterization of a novel human microsomal glutathione S-transferase with leukotriene C4 synthase activity and significant sequence identity to 5-lipoxygenase-activating protein and leukotriene C4 synthaseEvidence that human class Theta glutathione S-transferase T1-1 can catalyse the activation of dichloromethane, a liver and lung carcinogen in the mouse. Comparison of the tissue distribution of GST T1-1 with that of classes Alpha, Mu and Pi GST in hCysteinyl leukotriene receptor 1 is also a pyrimidinergic receptor and is expressed by human mast cellsMolecular cloning of the human leukotriene C4 synthase gene and assignment to chromosome 5q35Common structural features of MAPEG -- a widespread superfamily of membrane associated proteins with highly divergent functions in eicosanoid and glutathione metabolismThe organization and consequences of eicosanoid signalingMembrane-associated proteins in eicosanoid and glutathione metabolism (MAPEG). A widespread protein superfamilyRole of the 5-lipoxygenase-activating protein (FLAP) in murine acute inflammatory responsesCharacterization of mouse cysteinyl leukotriene receptors mCysLT1 and mCysLT2: differential pharmacological properties and tissue distributionThe membrane organization of leukotriene synthesisSite-directed mutagenesis of human leukotriene C4 synthase.Induction of IgE antibody responses by glutathione S-transferase from the German cockroach (Blattella germanica).Differential cerebral cortex transcriptomes of baboon neonates consuming moderate and high docosahexaenoic acid formulas.Asthma and leukotrienes: antileukotrienes as novel anti-asthmatic drugs.Prostaglandin D₂: a dominant mediator of aspirin-exacerbated respiratory disease.Thematic Review Series: Proteomics. An integrated omics analysis of eicosanoid biology.Inhibition of 5-lipoxygenase activity in mice during cuprizone-induced demyelination attenuates neuroinflammation, motor dysfunction and axonal damageCysteinyl leukotrienes impair hypoxic pulmonary vasoconstriction in endotoxemic mice.Allelic association and functional studies of promoter polymorphism in the leukotriene C4 synthase gene (LTC4S) in asthmaEmerging regulatory paradigms in glutathione metabolism.Cysteinyl leukotrienes and uridine diphosphate induce cytokine generation by human mast cells through an interleukin 4-regulated pathway that is inhibited by leukotriene receptor antagonistsT helper cell type 2 cytokines coordinately regulate immunoglobulin E-dependent cysteinyl leukotriene production by human cord blood-derived mast cells: profound induction of leukotriene C(4) synthase expression by interleukin 4.A leukotriene C4 synthase inhibitor with the backbone of 5-(5-methylene-4-oxo-4,5-dihydrothiazol-2-ylamino) isophthalic acid.Targeted lipidomics reveals mPGES-1-PGE2 as a therapeutic target for multiple sclerosis.Mechanisms of induction of cytosolic and microsomal glutathione transferase (GST) genes by xenobiotics and pro-inflammatory agents.A Single Amino Acid Difference between Mouse and Human 5-Lipoxygenase Activating Protein (FLAP) Explains the Speciation and Differential Pharmacology of Novel FLAP Inhibitors.Differential localization of 5- and 15-lipoxygenases to the nuclear envelope in RAW macrophages.14,15-Dehydroleukotriene A4: a specific substrate for leukotriene C4 synthase.Attenuated zymosan-induced peritoneal vascular permeability and IgE-dependent passive cutaneous anaphylaxis in mice lacking leukotriene C4 synthase.Targeted gene disruption reveals the role of cysteinyl leukotriene 1 receptor in the enhanced vascular permeability of mice undergoing acute inflammatory responses.Targeted gene disruption reveals the role of the cysteinyl leukotriene 2 receptor in increased vascular permeability and in bleomycin-induced pulmonary fibrosis in mice.LTA4 is converted to LTC4 by LTC4SMolecular Cloning of the Gene for Human Leukotriene C Synthase
P2860
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P2860
Molecular cloning and expression of human leukotriene-C4 synthase
description
1994 nî lūn-bûn
@nan
1994 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Molecular cloning and expression of human leukotriene-C4 synthase
@ast
Molecular cloning and expression of human leukotriene-C4 synthase
@en
Molecular cloning and expression of human leukotriene-C4 synthase
@nl
type
label
Molecular cloning and expression of human leukotriene-C4 synthase
@ast
Molecular cloning and expression of human leukotriene-C4 synthase
@en
Molecular cloning and expression of human leukotriene-C4 synthase
@nl
prefLabel
Molecular cloning and expression of human leukotriene-C4 synthase
@ast
Molecular cloning and expression of human leukotriene-C4 synthase
@en
Molecular cloning and expression of human leukotriene-C4 synthase
@nl
P2093
P2860
P356
P1476
Molecular cloning and expression of human leukotriene-C4 synthase
@en
P2093
D J Welsch
D P Creely
K J Mathis
P C Isakson
S D Hauser
P2860
P304
P356
10.1073/PNAS.91.21.9745
P407
P577
1994-10-11T00:00:00Z