A novel oncogene, ost, encodes a guanine nucleotide exchange factor that potentially links Rho and Rac signaling pathways
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A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange.A mammalian Rho-specific guanine-nucleotide exchange factor (p164-RhoGEF) without a pleckstrin homology domainp619, a giant protein related to the chromosome condensation regulator RCC1, stimulates guanine nucleotide exchange on ARF1 and Rab proteinsThe multidomain protein Trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain, and has separate rac-specific and rho-specific guanine nucleotide exchange factor domainsIQGAP1, a calmodulin-binding protein with a rasGAP-related domain, is a potential effector for cdc42HsIdentification of a novel Rac1-interacting protein involved in membrane rufflingCDC42 and FGD1 cause distinct signaling and transforming activities.Oligomerization of DH domain is essential for Dbl-induced transformationThe PRK2 kinase is a potential effector target of both Rho and Rac GTPases and regulates actin cytoskeletal organizationRhoG GTPase controls a pathway that independently activates Rac1 and Cdc42HsTruncation of C-mip (Tc-mip), a new proximal signaling protein, induces c-maf Th2 transcription factor and cytoskeleton reorganizationRegulated membrane localization of Tiam1, mediated by the NH2-terminal pleckstrin homology domain, is required for Rac-dependent membrane ruffling and C-Jun NH2-terminal kinase activationHuman ECT2 is an exchange factor for Rho GTPases, phosphorylated in G2/M phases, and involved in cytokinesisScambio, a novel guanine nucleotide exchange factor for RhoRho guanine nucleotide exchange factors: regulators of Rho GTPase activity in development and diseaseIL1RAPL1 associated with mental retardation and autism regulates the formation and stabilization of glutamatergic synapses of cortical neurons through RhoA signaling pathwayRom1p and Rom2p are GDP/GTP exchange proteins (GEPs) for the Rho1p small GTP binding protein in Saccharomyces cerevisiae.Identification of novel, evolutionarily conserved Cdc42p-interacting proteins and of redundant pathways linking Cdc24p and Cdc42p to actin polarization in yeastCdc42: An essential Rho-type GTPase controlling eukaryotic cell polarity.Ccpg1, a novel scaffold protein that regulates the activity of the Rho guanine nucleotide exchange factor DbsRho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein RhoActivation of Rac and Cdc42 by integrins mediates cell spreadingRegulation of vesicle transport and cell motility by Golgi-localized Dbs.The Caenorhabditis elegans gene unc-89, required fpr muscle M-line assembly, encodes a giant modular protein composed of Ig and signal transduction domainsA role for Rho in Ras transformation.The small GTP-binding protein Rho potentiates AP-1 transcription in T cells.A rac homolog is required for induction of hyphal growth in the dimorphic yeast Yarrowia lipolytica.Dependence of Dbl and Dbs transformation on MEK and NF-kappaB activation.Autoinhibition mechanism of proto-Dbl.Cytotoxic necrotizing factor type 2 produced by pathogenic Escherichia coli deamidates a gln residue in the conserved G-3 domain of the rho family and preferentially inhibits the GTPase activity of RhoA and rac1RhoGEF specificity mutants implicate RhoA as a target for Dbs transforming activity.A switch I mutant of Cdc42 exhibits less conformational freedom.FilGAP, a Rac-specific Rho GTPase-activating protein, is a novel prognostic factor for follicular lymphoma.Pheromone signalling in Saccharomyces cerevisiae requires the small GTP-binding protein Cdc42p and its activator CDC24.Identification of a novel susceptibility locus at 13q34 and refinement of the 20p12.2 region as a multi-signal locus associated with bladder cancer risk in individuals of European ancestry.Allosteric properties of PH domains in Arf regulatory proteins.Solution structure of an oncogenic mutant of Cdc42Hs.The rho-specific guanine nucleotide exchange factor Dbs regulates breast cancer cell migration.Advances in osteoarthritis geneticsFRAG1, a gene that potently activates fibroblast growth factor receptor by C-terminal fusion through chromosomal rearrangement.
P2860
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P2860
A novel oncogene, ost, encodes a guanine nucleotide exchange factor that potentially links Rho and Rac signaling pathways
description
1994 nî lūn-bûn
@nan
1994 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
A novel oncogene, ost, encodes ...... Rho and Rac signaling pathways
@ast
A novel oncogene, ost, encodes ...... Rho and Rac signaling pathways
@en
A novel oncogene, ost, encodes ...... Rho and Rac signaling pathways
@nl
type
label
A novel oncogene, ost, encodes ...... Rho and Rac signaling pathways
@ast
A novel oncogene, ost, encodes ...... Rho and Rac signaling pathways
@en
A novel oncogene, ost, encodes ...... Rho and Rac signaling pathways
@nl
prefLabel
A novel oncogene, ost, encodes ...... Rho and Rac signaling pathways
@ast
A novel oncogene, ost, encodes ...... Rho and Rac signaling pathways
@en
A novel oncogene, ost, encodes ...... Rho and Rac signaling pathways
@nl
P2093
P2860
P1433
P1476
A novel oncogene, ost, encodes ...... Rho and Rac signaling pathways
@en
P2093
P2860
P304
P407
P577
1994-10-17T00:00:00Z