Cell cycle- and cell growth-regulated proteolysis of mammalian CDC6 is dependent on APC-CDH1
about
The function of APC/CCdh1 in cell cycle and beyondArsenite-induced Cdc25C Degradation is through the KEN-box and Ubiquitin-proteasome PathwayInhibition of Cdh1-APC by the MAD2-related protein MAD2L2: a novel mechanism for regulating Cdh1Phosphorylation of multifunctional nucleolar protein nucleophosmin (NPM1) by aurora kinase B is critical for mitotic progressionAPC/C(Cdh1) targets brain-specific kinase 2 (BRSK2) for degradation via the ubiquitin-proteasome pathwayIdas, a novel phylogenetically conserved geminin-related protein, binds to geminin and is required for cell cycle progressionThe regulated association of Cdt1 with minichromosome maintenance proteins and Cdc6 in mammalian cellsTiming of APC/C substrate degradation is determined by fzy/fzr specificity of destruction boxes.Regulation of CDC6, geminin, and CDT1 in human cells that undergo polyploidizationHuman cytomegalovirus infection leads to accumulation of geminin and inhibition of the licensing of cellular DNA replication.Securin degradation is mediated by fzy and fzr, and is required for complete chromatid separation but not for cytokinesisStability, chromatin association and functional activity of mammalian pre-replication complex proteins during the cell cycleInvolvement of human MCM8 in prereplication complex assembly by recruiting hcdc6 to chromatinHuman geminin promotes pre-RC formation and DNA replication by stabilizing CDT1 in mitosisSmad3 recruits the anaphase-promoting complex for ubiquitination and degradation of SnoNProtein phosphatase 2A is targeted to cell division control protein 6 by a calcium-binding regulatory subunitReplication licensing and cancer--a fatal entanglement?Mechanisms to control rereplication and implications for cancer.Early mitotic degradation of the homeoprotein HOXC10 is potentially linked to cell cycle progressionThe Arabidopsis anaphase-promoting complex or cyclosome: molecular and genetic characterization of the APC2 subunitLicensing for DNA replication requires a strict sequential assembly of Cdc6 and Cdt1 onto chromatin in Xenopus egg extractsInsights into APC/C: from cellular function to diseases and therapeuticsFunctional characterization of Anaphase Promoting Complex/Cyclosome (APC/C) E3 ubiquitin ligases in tumorigenesisSpatio-temporal regulation of the human licensing factor Cdc6 in replication and mitosis.Orc1 Binding to Mitotic Chromosomes Precedes Spatial Patterning during G1 Phase and Assembly of the Origin Recognition Complex in Human Cells.The SCF(Skp2) ubiquitin ligase complex interacts with the human replication licensing factor Cdt1 and regulates Cdt1 degradationCell cycle-dependent proteolysis and phosphorylation of human Mcm10Cyclin-dependent kinases prevent DNA re-replication through multiple mechanismsCDC6: from DNA replication to cell cycle checkpoints and oncogenesisSeparate SCF(CDC4) recognition elements target Cdc6 for proteolysis in S phase and mitosis.APC/C-mediated destruction of the centrosomal kinase Nek2A occurs in early mitosis and depends upon a cyclin A-type D-boxDual mode of degradation of Cdc25 A phosphataseCell cycle-regulated protein abundance changes in synchronously proliferating HeLa cells include regulation of pre-mRNA splicing proteinsMammalian Orc1 protein is selectively released from chromatin and ubiquitinated during the S-to-M transition in the cell division cycle.Cdc6 chromatin affinity is unaffected by serine-54 phosphorylation, S-phase progression, and overexpression of cyclin A.Selective small-molecule inhibitor reveals critical mitotic functions of human CDK1Function of COP9 signalosome in regulation of mouse oocytes meiosis by regulating MPF activity and securing degradationDown-regulation of Cdc6, a cell cycle regulatory gene, in prostate cancer.APC/C-CCS52A complexes control meristem maintenance in the Arabidopsis rootTargeted destruction of DNA replication protein Cdc6 by cell death pathways in mammals and yeast.
P2860
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P2860
Cell cycle- and cell growth-regulated proteolysis of mammalian CDC6 is dependent on APC-CDH1
description
2000 nî lūn-bûn
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2000 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Cell cycle- and cell growth-re ...... CDC6 is dependent on APC-CDH1
@ast
Cell cycle- and cell growth-re ...... CDC6 is dependent on APC-CDH1
@en
Cell cycle- and cell growth-re ...... CDC6 is dependent on APC-CDH1
@nl
type
label
Cell cycle- and cell growth-re ...... CDC6 is dependent on APC-CDH1
@ast
Cell cycle- and cell growth-re ...... CDC6 is dependent on APC-CDH1
@en
Cell cycle- and cell growth-re ...... CDC6 is dependent on APC-CDH1
@nl
prefLabel
Cell cycle- and cell growth-re ...... CDC6 is dependent on APC-CDH1
@ast
Cell cycle- and cell growth-re ...... CDC6 is dependent on APC-CDH1
@en
Cell cycle- and cell growth-re ...... CDC6 is dependent on APC-CDH1
@nl
P2093
P2860
P3181
P356
P1433
P1476
Cell cycle- and cell growth-re ...... CDC6 is dependent on APC-CDH1
@en
P2093
B O Petersen
C Gieffers
C Matteucci
E Lazzerini Denchi
F Marinoni
J M Peters
M Melixetian
P2860
P304
P3181
P356
10.1101/GAD.832500
P407
P577
2000-09-01T00:00:00Z