The affected gene underlying the class K glycosylphosphatidylinositol (GPI) surface protein defect codes for the GPI transamidase
about
Gaa1p and gpi8p are components of a glycosylphosphatidylinositol (GPI) transamidase that mediates attachment of GPI to proteinsPIG-S and PIG-T, essential for GPI anchor attachment to proteins, form a complex with GAA1 and GPI8Two subunits of glycosylphosphatidylinositol transamidase, GPI8 and PIG-T, form a functionally important intermolecular disulfide bridgeStructural requirements for the recruitment of Gaa1 into a functional glycosylphosphatidylinositol transamidase complexA conserved proline in the last transmembrane segment of Gaa1 is required for glycosylphosphatidylinositol (GPI) recognition by GPI transamidaseHuman PIG-U and yeast Cdc91p are the fifth subunit of GPI transamidase that attaches GPI-anchors to proteinsBiosynthesis and deficiencies of glycosylphosphatidylinositolPIG-W is critical for inositol acylation but not for flipping of glycosylphosphatidylinositol-anchor.Deletion of GPI7, a yeast gene required for addition of a side chain to the glycosylphosphatidylinositol (GPI) core structure, affects GPI protein transport, remodeling, and cell wall integrity.Genes for glycosylphosphatidylinositol toxin biosynthesis in Plasmodium falciparum.Post-translational GPI lipid anchor modification of proteins in kingdoms of life: analysis of protein sequence data from complete genomes.Biosynthesis of glycosylphosphatidylinositols in mammals and unicellular microbes.Early events in glycosylphosphatidylinositol anchor addition. substrate proteins associate with the transamidase subunit gpi8p.Biosynthesis of GPI-anchored proteins: special emphasis on GPI lipid remodeling.Leishmania mexicana mutants lacking glycosylphosphatidylinositol (GPI):protein transamidase provide insights into the biosynthesis and functions of GPI-anchored proteins.Essential roles for GPI-anchored proteins in African trypanosomes revealed using mutants deficient in GPI8Profiling the expression pattern of GPI transamidase complex subunits in human cancer.GPI transamidase of Trypanosoma brucei has two previously uncharacterized (trypanosomatid transamidase 1 and 2) and three common subunitsMammalian glycophosphatidylinositol anchor transfer to proteins and posttransfer deacylation.Alterations of GPI transamidase subunits in head and neck squamous carcinoma.Recent developments in the molecular, biochemical and functional characterization of GPI8 and the GPI-anchoring mechanism [review].Thematic review series: lipid posttranslational modifications. GPI anchoring of protein in yeast and mammalian cells, or: how we learned to stop worrying and love glycophospholipids.Biosynthesis of glycosylphosphatidylinositol is essential to the survival of the protozoan parasite Toxoplasma gondii.Soluble GPI8 restores glycosylphosphatidylinositol anchoring in a trypanosome cell-free system depleted of lumenal endoplasmic reticulum proteins.The human NKG2D ligand ULBP2 can be expressed at the cell surface with or without a GPI anchor and both forms can activate NK cells.Cloning of murine glycosyl phosphatidylinositol anchor attachment protein, GPAA1.Endoplasmic reticulum proteins involved in glycosylphosphatidylinositol-anchor attachment: photocrosslinking studies in a cell-free system.Processing and trafficking of Leishmania mexicana GP63. Analysis using GP18 mutants deficient in glycosylphosphatidylinositol protein anchoring.The glycan core of GPI-anchored proteins modulates aerolysin binding but is not sufficient: the polypeptide moiety is required for the toxin-receptor interaction.In vitro translation in a cell-free system from Trypanosoma brucei yields glycosylated and glycosylphosphatidylinositol-anchored proteins.uPAR precursor + acyl-GPI -> uPAR-acyl-GPI + uPAR propeptideThe Role of LORELEI in Pollen Tube Reception at the Interface of the Synergid Cell and Pollen Tube Requires the Modified Eight-Cysteine Motif and the Receptor-Like Kinase FERONIA.Cloning, Expression, and Characterization of the acyl-CoA-binding Protein in African Trypanosomes
P2860
Q22254022-18721E72-F0BF-416C-AEEA-16EF8967420EQ24291511-D6231898-BF9B-4399-A217-063569E3CD54Q24294601-58634934-4B01-494E-9003-47A3F565BB01Q24299146-B533A356-368B-4E03-86A4-8197951E33E1Q24301298-EA240DFF-B279-4848-B7C7-D1C6B8083906Q24304495-5B84CC86-AEAD-4AB9-A205-34B87C0C473CQ26998348-47B8BD11-616F-4674-AC12-4BF258B286DBQ27937797-C8D02D49-258E-4FF3-B6E8-A24669165AB9Q27939479-3303E3D2-8DBB-46DA-B17E-691BFCF2E931Q27972986-C7D285FF-B1CD-4D33-8F4B-FBFD9BB9578AQ31891551-A96758CC-6152-4EC1-93AA-EAD94CB4A7F8Q33672095-EEAA03DE-7947-457F-ABE8-5AD8A3174A23Q33940437-1BF2CEA3-8191-4D82-9CC7-9005254D81B0Q34045400-80F39938-F1CC-4417-8B9E-659EED8D8A74Q34701006-6CE8C262-4859-4EF5-B88F-D2AB07CFFFAEQ34814046-3449293A-C402-4F70-A5DF-63DEE892EC52Q34865473-7A49B81C-3F35-47B0-85AA-AB8DF78E5206Q35977478-F5FE9A34-421C-40F0-BAE1-52EA5304D62EQ36263963-893B791E-9BFE-497E-8681-0499EEBDF79AQ36389443-909A340C-FBCD-4141-9F5F-4A5132C1195BQ36511643-56ADA5AF-1C1F-4A3B-8D90-A61268F232F5Q36759924-D0EEC6D5-4EE5-4B00-A58F-473D9EFC32A5Q39981750-8452C78A-6910-44D5-9F07-E61B0388E5A5Q41822577-41E15E34-0D44-4947-99C2-2FF07E8151ECQ42573534-DED60259-C998-436D-B9F2-762B8B6DC5B1Q42799676-1E666526-7624-4B95-A0CE-918731AA5FDCQ43572395-06EB5AA0-BE4C-42C6-A85A-8AAEB233B7C5Q44005241-9624D913-3DB0-4561-B0BC-6749496C7835Q45711489-BB535749-B929-4134-A09F-971421D205A3Q46903085-7F18125A-6FE0-443B-8C9B-79653F0257FCQ50296184-90A31706-D3F0-4DD2-8E6D-831E791CA818Q50908561-A47D3803-7504-4A0D-B6FE-6C49D4D1DD7BQ58867216-D3125E2F-C9FE-4C89-BC7E-366FD5D588B0
P2860
The affected gene underlying the class K glycosylphosphatidylinositol (GPI) surface protein defect codes for the GPI transamidase
description
1997 nî lūn-bûn
@nan
1997 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
The affected gene underlying t ...... codes for the GPI transamidase
@ast
The affected gene underlying t ...... codes for the GPI transamidase
@en
The affected gene underlying t ...... codes for the GPI transamidase
@nl
type
label
The affected gene underlying t ...... codes for the GPI transamidase
@ast
The affected gene underlying t ...... codes for the GPI transamidase
@en
The affected gene underlying t ...... codes for the GPI transamidase
@nl
prefLabel
The affected gene underlying t ...... codes for the GPI transamidase
@ast
The affected gene underlying t ...... codes for the GPI transamidase
@en
The affected gene underlying t ...... codes for the GPI transamidase
@nl
P2093
P2860
P356
P1476
The affected gene underlying t ...... codes for the GPI transamidase
@en
P2093
P2860
P304
P356
10.1073/PNAS.94.23.12580
P407
P577
1997-11-11T00:00:00Z