Yeast Gaa1p is required for attachment of a completed GPI anchor onto proteins.
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Gaa1p and gpi8p are components of a glycosylphosphatidylinositol (GPI) transamidase that mediates attachment of GPI to proteinsPIG-S and PIG-T, essential for GPI anchor attachment to proteins, form a complex with GAA1 and GPI8Endoplasmic reticulum localization of Gaa1 and PIG-T, subunits of the glycosylphosphatidylinositol transamidase complexHuman Smp3p adds a fourth mannose to yeast and human glycosylphosphatidylinositol precursors in vivoStructural requirements for the recruitment of Gaa1 into a functional glycosylphosphatidylinositol transamidase complexA conserved proline in the last transmembrane segment of Gaa1 is required for glycosylphosphatidylinositol (GPI) recognition by GPI transamidaseHuman PIG-U and yeast Cdc91p are the fifth subunit of GPI transamidase that attaches GPI-anchors to proteinsMolecular cloning of human homolog of yeast GAA1 which is required for attachment of glycosylphosphatidylinositols to proteinsPIG-A and PIG-H, which participate in glycosylphosphatidylinositol anchor biosynthesis, form a protein complex in the endoplasmic reticulumYeast Gpi8p is essential for GPI anchor attachment onto proteinsThe affected gene underlying the class K glycosylphosphatidylinositol (GPI) surface protein defect codes for the GPI transamidaseBiosynthesis and deficiencies of glycosylphosphatidylinositolGWT1 gene is required for inositol acylation of glycosylphosphatidylinositol anchors in yeast.Different subcellular localization of Saccharomyces cerevisiae HMG-CoA reductase isozymes at elevated levels corresponds to distinct endoplasmic reticulum membrane proliferations.Restrictive glycosylphosphatidylinositol anchor synthesis in cwh6/gpi3 yeast cells causes aberrant biogenesis of cell wall proteinsYeast ARV1 is required for efficient delivery of an early GPI intermediate to the first mannosyltransferase during GPI assembly and controls lipid flow from the endoplasmic reticulum.Glycosylphosphatidylinositol biosynthesis defects in Gpi11p- and Gpi13p-deficient yeast suggest a branched pathway and implicate gpi13p in phosphoethanolamine transfer to the third mannose.Deficiencies in the endoplasmic reticulum (ER)-membrane protein Gab1p perturb transfer of glycosylphosphatidylinositol to proteins and cause perinuclear ER-associated actin bar formationThe GPI transamidase complex of Saccharomyces cerevisiae contains Gaa1p, Gpi8p, and Gpi16p.Molecular basis of cell integrity and morphogenesis in Saccharomyces cerevisiaeGPI7 involved in glycosylphosphatidylinositol biosynthesis is essential for yeast cell separation.Saccharomyces cerevisiae GPI10, the functional homologue of human PIG-B, is required for glycosylphosphatidylinositol-anchor synthesisDeletion of GPI7, a yeast gene required for addition of a side chain to the glycosylphosphatidylinositol (GPI) core structure, affects GPI protein transport, remodeling, and cell wall integrity.The essential Smp3 protein is required for addition of the side-branching fourth mannose during assembly of yeast glycosylphosphatidylinositols.MCD4 encodes a conserved endoplasmic reticulum membrane protein essential for glycosylphosphatidylinositol anchor synthesis in yeastGenes for glycosylphosphatidylinositol toxin biosynthesis in Plasmodium falciparum.Purification, cloning and characterization of a GPI inositol deacylase from Trypanosoma brucei.Expression cloning of PIG-L, a candidate N-acetylglucosaminyl-phosphatidylinositol deacetylaseThe Schizosaccharomyces pombe GPI8 gene complements a Saccharomyces cerevisiae GPI8 anchoring mutant.Post-translational GPI lipid anchor modification of proteins in kingdoms of life: analysis of protein sequence data from complete genomes.Surface proteins of gram-positive bacteria and mechanisms of their targeting to the cell wall envelope.Biosynthesis of glycosylphosphatidylinositols in mammals and unicellular microbes.Protein Lipidation As a Regulator of Apoptotic Calcium Release: Relevance to Cancer.Lipid remodeling leads to the introduction and exchange of defined ceramides on GPI proteins in the ER and Golgi of Saccharomyces cerevisiae.Identification of a species-specific inhibitor of glycosylphosphatidylinositol synthesis.Recent developments in the cell biology and biochemistry of glycosylphosphatidylinositol lipids (review).Comparative Analysis of Protein Glycosylation Pathways in Humans and the Fungal Pathogen Candida albicans.Early events in glycosylphosphatidylinositol anchor addition. substrate proteins associate with the transamidase subunit gpi8p.Transamidase subunit GAA1/GPAA1 is a M28 family metallo-peptide-synthetase that catalyzes the peptide bond formation between the substrate protein's omega-site and the GPI lipid anchor's phosphoethanolamine.Biosynthesis of GPI-anchored proteins: special emphasis on GPI lipid remodeling.
P2860
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P2860
Yeast Gaa1p is required for attachment of a completed GPI anchor onto proteins.
description
1995 nî lūn-bûn
@nan
1995 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Yeast Gaa1p is required for attachment of a completed GPI anchor onto proteins.
@ast
Yeast Gaa1p is required for attachment of a completed GPI anchor onto proteins.
@en
Yeast Gaa1p is required for attachment of a completed GPI anchor onto proteins.
@nl
type
label
Yeast Gaa1p is required for attachment of a completed GPI anchor onto proteins.
@ast
Yeast Gaa1p is required for attachment of a completed GPI anchor onto proteins.
@en
Yeast Gaa1p is required for attachment of a completed GPI anchor onto proteins.
@nl
prefLabel
Yeast Gaa1p is required for attachment of a completed GPI anchor onto proteins.
@ast
Yeast Gaa1p is required for attachment of a completed GPI anchor onto proteins.
@en
Yeast Gaa1p is required for attachment of a completed GPI anchor onto proteins.
@nl
P2860
P356
P1476
Yeast Gaa1p is required for attachment of a completed GPI anchor onto proteins.
@en
P2093
D Hamburger
P2860
P304
P356
10.1083/JCB.129.3.629
P407
P577
1995-05-01T00:00:00Z