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Serotonin 5-HT2 receptor interactions with dopamine function: implications for therapeutics in cocaine use disorderFull and Partial Agonism of a Designed Enzyme SwitchCentral serotonin-2A (5-HT2A) receptor dysfunction in depression and epilepsy: the missing link?Functional interactions between 5-HT2A and presynaptic 5-HT1A receptor-based responses in mice genetically deficient in the serotonin 5-HT transporter (SERT)Genetic deletion of p90 ribosomal S6 kinase 2 alters patterns of 5-hydroxytryptamine 2A serotonin receptor functional selectivity.Neuronal ablation of p-Akt at Ser473 leads to altered 5-HT1A/2A receptor functionQuantitative phosphoproteomics dissection of seven-transmembrane receptor signaling using full and biased agonists.Discovery of β-arrestin-biased dopamine D2 ligands for probing signal transduction pathways essential for antipsychotic efficacy.Ligand-dependent conformations and dynamics of the serotonin 5-HT(2A) receptor determine its activation and membrane-driven oligomerization propertiesDiscovery of GPCR ligands for probing signal transduction pathways.Structure-functional selectivity relationship studies of β-arrestin-biased dopamine D₂ receptor agonists.Insights into the regulation of 5-HT2A serotonin receptors by scaffolding proteins and kinases.Engineered GPCRs as tools to modulate signal transduction.Irving Page Lecture: 5-HT(2A) serotonin receptor biology: interacting proteins, kinases and paradoxical regulation.Lorcaserin (APD356), a selective 5-HT(2C) agonist, reduces body weight in obese men and women.Cocaine potentiates multiple 5-HT2A receptor signaling pathways and is associated with decreased phosphorylation of 5-HT2A receptors in vivo.
P2860
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P2860
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Arresting serotonin
@ast
Arresting serotonin
@en
Arresting serotonin
@nl
type
label
Arresting serotonin
@ast
Arresting serotonin
@en
Arresting serotonin
@nl
prefLabel
Arresting serotonin
@ast
Arresting serotonin
@en
Arresting serotonin
@nl
P2860
P356
P1476
Arresting serotonin
@en
P2093
Atheir Abbas
Bryan L Roth
P2860
P356
10.1073/PNAS.0711335105
P407
P577
2008-01-22T00:00:00Z