Halofuginone inhibits TH17 cell differentiation by activating the amino acid starvation response - Wikidata - thesis-toulmin - TriplyDB

Halofuginone inhibits TH17 cell differentiation by activating the amino acid starvation response

Halofuginone inhibits TH17 cell differentiation by activating the amino acid starvation response

http://www.wikidata.org/entity/Q24648465

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Genes, tolerance and systemic autoimmunity Recent advances in understanding the molecular mechanisms of the development and function of Th17 cells Immunotherapy of systemic sclerosis Mesenchymal Stem Cells and Myeloid Derived Suppressor Cells: Common Traits in Immune Regulation Immune Cells and Inflammation in Diabetic Nephropathy Targeting the indoleamine 2,3-dioxygenase pathway in cancer Evolutionary Limitation and Opportunities for Developing tRNA Synthetase Inhibitors with 5-Binding-Mode Classification Metabolic reprogramming and metabolic dependency in T cells Amino acid sensing in dietary-restriction-mediated longevity: roles of signal-transducing kinases GCN2 and TOR ATP-directed capture of bioactive herbal-based medicine on human tRNA synthetase Immunometabolism of regulatory T cells Identification of Baicalin as an immunoregulatory compound by controlling T(H)17 cell differentiation Halofuginone Synergistically Enhances Anti-Proliferation of Rapamycin in T Cells and Reduces Cytotoxicity of Cyclosporine in Cultured Renal Tubular Epithelial Cells Halofuginone inhibits the establishment and progression of melanoma bone metastases.The eIF2 kinase GCN2 is essential for the murine immune system to adapt to amino acid deprivation by asparaginase Structural basis for full-spectrum inhibition of translational functions on a tRNA synthetase Exogenous amino acids are essential for interleukin-7 induced CD8 T cell growth. [corrected]Conformational changes in human prolyl-tRNA synthetase upon binding of the substrates proline and ATP and the inhibitor halofuginone.The role of placental tryptophan catabolism The presence of IL-17A and T helper 17 cells in experimental mouse brain tumors and human glioma Th 17 cells interplay with Foxp3+ Tregs in regulation of inflammation and autoimmunity.Th17 cells and IL-17 in protective immunity to vaginal candidiasis.Microarray profiling reveals the integrated stress response is activated by halofuginone in mammary epithelial cells.Halofuginone has anti-proliferative effects in acute promyelocytic leukemia by modulating the transforming growth factor beta signaling pathway.Suppression of ongoing experimental arthritis by a chinese herbal formula (huo-luo-xiao-ling dan) involves changes in antigen-induced immunological and biochemical mediators of inflammation.Halofuginone and other febrifugine derivatives inhibit prolyl-tRNA synthetase.Indoleamine 2,3 dioxygenase and metabolic control of immune responses.IDO inhibits a tryptophan sufficiency signal that stimulates mTOR: A novel IDO effector pathway targeted by D-1-methyl-tryptophan.Involvement of host stroma cells and tissue fibrosis in pancreatic tumor development in transgenic mice.Vitamin D suppresses Th17 cytokine production by inducing C/EBP homologous protein (CHOP) expression IDO upregulates regulatory T cells via tryptophan catabolite and suppresses encephalitogenic T cell responses in experimental autoimmune encephalomyelitis Th17 and regulatory T cells: implications for AIDS pathogenesis Phase II AIDS Malignancy Consortium trial of topical halofuginone in AIDS-related Kaposi sarcoma.Tryptophan catabolism by indoleamine 2,3-dioxygenase 1 alters the balance of TH17 to regulatory T cells in HIV disease How tolerogenic dendritic cells induce regulatory T cells Concise review: chemical approaches for modulating lineage-specific stem cells and progenitors.Translational mini-review series on Th17 cells: function and regulation of human T helper 17 cells in health and disease.Calcium signaling via Orai1 is essential for induction of the nuclear orphan receptor pathway to drive Th17 differentiation Metabolic Control of Th17 Cell Generation and CNS Inflammation HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells.

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Halofuginone inhibits TH17 cell differentiation by activating the amino acid starvation response

http://www.wikidata.org/entity/Q24648465

description

2009 nî lūn-bûn

@nan

2009 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հունիսին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

Halofuginone inhibits TH17 cel ...... amino acid starvation response

@ast

Halofuginone inhibits TH17 cel ...... amino acid starvation response

@en

Halofuginone inhibits TH17 cel ...... amino acid starvation response

@nl

type

label

Halofuginone inhibits TH17 cel ...... amino acid starvation response

@ast

Halofuginone inhibits TH17 cel ...... amino acid starvation response

@en

Halofuginone inhibits TH17 cel ...... amino acid starvation response

@nl

prefLabel

Halofuginone inhibits TH17 cel ...... amino acid starvation response

@ast

Halofuginone inhibits TH17 cel ...... amino acid starvation response

@en

Halofuginone inhibits TH17 cel ...... amino acid starvation response

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Halofuginone inhibits TH17 cel ...... amino acid starvation response

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Ava Rhule-Smith

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Rachel E Lefebvre

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P2860

IL-17 and Th17 Cells

Signal integration in the endoplasmic reticulum unfolded protein response

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

TH17 cells in development: an updated view of their molecular identity and genetic programming

STAT3 regulates cytokine-mediated generation of inflammatory helper T cells

Transforming growth factor-beta regulation of immune responses

Regulated translation initiation controls stress-induced gene expression in mammalian cells

T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma

XBP-1 regulates a subset of endoplasmic reticulum resident chaperone genes in the unfolded protein response

An integrated stress response regulates amino acid metabolism and resistance to oxidative stress

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