IDO inhibits a tryptophan sufficiency signal that stimulates mTOR: A novel IDO effector pathway targeted by D-1-methyl-tryptophan.
about
Targeting the indoleamine 2,3-dioxygenase pathway in cancerThe mTOR pathway and integrating immune regulationThe role of IDO in brain tumor immunotherapyMetabolic regulation of regulatory T cell development and functionIDO2 in Immunomodulation and Autoimmune DiseaseThe Novel PKCθ from Benchtop to ClinicIDO2: A Pathogenic Mediator of Inflammatory AutoimmunityMeat Intake and the Dose of Vitamin B3 - Nicotinamide: Cause of the Causes of Disease Transitions, Health Divides, and Health Futures?The role of placental tryptophan catabolismNutrient Sensing via mTOR in T Cells Maintains a Tolerogenic Microenvironment.Tryptophan-catabolizing enzymes - party of threeIDO2 is critical for IDO1-mediated T-cell regulation and exerts a non-redundant function in inflammation.IDO2 is a critical mediator of autoantibody production and inflammatory pathogenesis in a mouse model of autoimmune arthritis.Indoleamine 2,3-dioxygenase pathways of pathogenic inflammation and immune escape in cancerA first in man phase I trial of the oral immunomodulator, indoximod, combined with docetaxel in patients with metastatic solid tumors1-Methyl-tryptophan synergizes with methotrexate to alleviate arthritis in a mouse model of arthritis.The Host Microbiome Regulates and Maintains Human Health: A Primer and Perspective for Non-Microbiologists.Cancer Immunotherapy by Targeting IDO1/TDO and Their Downstream Effectors.Tryptophan-degrading enzymes in tumoral immune resistance.Indoleamine-2,3-dioxygenase (IDO) metabolic activity is detrimental for cervical cancer patient survival.Kynurenine and uric acid levels in chronic myeloid leukemia patients.Exogenous Tryptophan Promotes Cutaneous Wound Healing of Chronically Stressed Mice through Inhibition of TNF-α and IDO Activation.1-Methyl-D-tryptophan potentiates TGF-β-induced epithelial-mesenchymal transition in T24 human bladder cancer cells.Salmonella overcomes tumor immune tolerance by inhibition of tumor indoleamine 2, 3-dioxygenase 1 expressionIndoleamine 2,3-dioxygenase activity and clinical outcome following induction chemotherapy and concurrent chemoradiation in Stage III non-small cell lung cancer.IDO2 Modulates T Cell-Dependent Autoimmune Responses through a B Cell-Intrinsic Mechanism.Indoleamine 2,3-dioxygenase is a critical resistance mechanism in antitumor T cell immunotherapy targeting CTLA-4.A phase I study of indoximod in patients with advanced malignanciesNeutrophils are Essential in Short Hairpin RNA of Indoleamine 2,3- Dioxygenase Mediated-antitumor EfficiencyMesenchymal stromal cells as vehicles of tetravalent bispecific Tandab (CD3/CD19) for the treatment of B cell lymphoma combined with IDO pathway inhibitor D-1-methyl-tryptophan.Chlamydia-host cell interaction not only from a bird's eye view: some lessons from Chlamydia psittaci.Indoleamine 2,3-dioxygenase 2 (IDO2) and the kynurenine pathway: characteristics and potential roles in health and disease.Metabolic control of tumour progression and antitumour immunityImmunostimulatory activity of lifespan-extending agents.Therapeutic targeting of inflammation and tryptophan metabolism in colon and gastrointestinal cancer.Molecular Pathways: Targeting IDO1 and Other Tryptophan Dioxygenases for Cancer Immunotherapy.High immunosuppressive burden in cancer patients: a major hurdle for cancer immunotherapy.Suppression of Th1 differentiation by tryptophan supplementation in vivo.Metabolic regulation of immune responses: therapeutic opportunities.The stress kinase GCN2 does not mediate suppression of antitumor T cell responses by tryptophan catabolism in experimental melanomas.
P2860
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P2860
IDO inhibits a tryptophan sufficiency signal that stimulates mTOR: A novel IDO effector pathway targeted by D-1-methyl-tryptophan.
description
2012 nî lūn-bûn
@nan
2012 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
IDO inhibits a tryptophan suff ...... eted by D-1-methyl-tryptophan.
@ast
IDO inhibits a tryptophan suff ...... eted by D-1-methyl-tryptophan.
@en
IDO inhibits a tryptophan suff ...... eted by D-1-methyl-tryptophan.
@nl
type
label
IDO inhibits a tryptophan suff ...... eted by D-1-methyl-tryptophan.
@ast
IDO inhibits a tryptophan suff ...... eted by D-1-methyl-tryptophan.
@en
IDO inhibits a tryptophan suff ...... eted by D-1-methyl-tryptophan.
@nl
prefLabel
IDO inhibits a tryptophan suff ...... eted by D-1-methyl-tryptophan.
@ast
IDO inhibits a tryptophan suff ...... eted by D-1-methyl-tryptophan.
@en
IDO inhibits a tryptophan suff ...... eted by D-1-methyl-tryptophan.
@nl
P2093
P2860
P356
P1433
P1476
IDO inhibits a tryptophan suff ...... geted by D-1-methyl-tryptophan
@en
P2093
Charles J Link
George C Prendergast
James B Duhadaway
Mario R Mautino
Nicholas N Vahanian
Richard Metz
Sonja Rust
P2860
P304
P356
10.4161/ONCI.21716
P577
2012-12-01T00:00:00Z