The ubiquitin ligase Nedd4-1 is dispensable for the regulation of PTEN stability and localization
about
Regulation of Rap2A by the ubiquitin ligase Nedd4-1 controls neurite developmentX-linked inhibitor of apoptosis protein (XIAP) regulates PTEN ubiquitination, content, and compartmentalizationNovel control of S phase of the cell cycle by ubiquitin-conjugating enzyme H7Purinergic receptor-mediated rapid depletion of nuclear phosphorylated Akt depends on pleckstrin homology domain leucine-rich repeat phosphatase, calcineurin, protein phosphatase 2A, and PTEN phosphatasesEmerging role of Lys-63 ubiquitination in protein kinase and phosphatase activation and cancer developmentE3 ligase Nedd4 promotes axon branching by downregulating PTENUbiquitin-dependent regulation of phospho-AKT dynamics by the ubiquitin E3 ligase, NEDD4-1, in the insulin-like growth factor-1 responseNedd4 and Nedd4-2: closely related ubiquitin-protein ligases with distinct physiological functionsUbiquitylation as a Rheostat for TCR Signaling: From Targeted Approaches Toward Global ProfilingFocus on PTEN RegulationPhosphoinositides: tiny lipids with giant impact on cell regulationRsp5/Nedd4 is the main ubiquitin ligase that targets cytosolic misfolded proteins following heat stress.Nedd4 E3 ubiquitin ligase promotes cell proliferation and autophagyPTEN is a protein tyrosine phosphatase for IRS1Phosphorylation of Kif26b promotes its polyubiquitination and subsequent proteasomal degradation during kidney developmentThe ubiquitin ligase Nedd4-1 is required for heart development and is a suppressor of thrombospondin-1E3 Ubiquitin Ligase NEDD4 Promotes Influenza Virus Infection by Decreasing Levels of the Antiviral Protein IFITM3Comparison of substrate specificity of the ubiquitin ligases Nedd4 and Nedd4-2 using proteome arraysExosome-mediated delivery of the intrinsic C-terminus domain of PTEN protects it from proteasomal degradation and ablates tumorigenesisRFP-mediated ubiquitination of PTEN modulates its effect on AKT activationRegulation of glioma migration and invasion via modification of Rap2a activity by the ubiquitin ligase Nedd4-1.Functional interaction of phosphatase and tensin homologue (PTEN) with the E3 ligase NEDD4-1 during neuronal response to zinc.Cdh1, a substrate-recruiting component of anaphase-promoting complex/cyclosome (APC/C) ubiquitin E3 ligase, specifically interacts with phosphatase and tensin homolog (PTEN) and promotes its removal from chromatin.NEDD4 controls spermatogonial stem cell homeostasis and stress response by regulating messenger ribonucleoprotein complexes.A role for the ubiquitin ligase Nedd4 in membrane sorting of LAPTM4 proteins.Oncogenic role of the E3 ubiquitin ligase NEDD4-1, a PTEN negative regulator, in non-small-cell lung carcinomas.p34 is a novel regulator of the oncogenic behavior of NEDD4-1 and PTEN.RAKing in AKT: a tumor suppressor function for the intracellular tyrosine kinase FRK.Ubiquitin E3 ligase Nedd4-1 acts as a downstream target of PI3K/PTEN-mTORC1 signaling to promote neurite growth.Ubiquitin becomes ubiquitous in cancer: emerging roles of ubiquitin ligases and deubiquitinases in tumorigenesis and as therapeutic targets.The antiproliferative response of indole-3-carbinol in human melanoma cells is triggered by an interaction with NEDD4-1 and disruption of wild-type PTEN degradationNedd4-1 is an exceptional prognostic biomarker for gastric cardia adenocarcinoma and functionally associated with metastasis.AMPK/TSC2/mTOR-signaling intermediates are not necessary for LKB1-mediated nuclear retention of PTEN tumor suppressorNEDD4-1 regulates migration and invasion of glioma cells through CNrasGEF ubiquitination in vitro.AKT1/BRCA1 in the control of homologous recombination and genetic stability: the missing link between hereditary and sporadic breast cancers.Ndfip1 regulates nuclear Pten import in vivo to promote neuronal survival following cerebral ischemia.The chaperone-assisted E3 ligase C terminus of Hsc70-interacting protein (CHIP) targets PTEN for proteasomal degradation.E3 ubiquitin ligase Cbl-b regulates Pten via Nedd4 in T cells independently of its ubiquitin ligase activityPTEN and NEDD4 in Human Breast Carcinoma.Is NEDD4-1 a negative regulator of phosphatase and tensin homolog in gastric carcinogenesis?
P2860
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P2860
The ubiquitin ligase Nedd4-1 is dispensable for the regulation of PTEN stability and localization
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
The ubiquitin ligase Nedd4-1 i ...... TEN stability and localization
@ast
The ubiquitin ligase Nedd4-1 i ...... TEN stability and localization
@en
The ubiquitin ligase Nedd4-1 i ...... TEN stability and localization
@nl
type
label
The ubiquitin ligase Nedd4-1 i ...... TEN stability and localization
@ast
The ubiquitin ligase Nedd4-1 i ...... TEN stability and localization
@en
The ubiquitin ligase Nedd4-1 i ...... TEN stability and localization
@nl
prefLabel
The ubiquitin ligase Nedd4-1 i ...... TEN stability and localization
@ast
The ubiquitin ligase Nedd4-1 i ...... TEN stability and localization
@en
The ubiquitin ligase Nedd4-1 i ...... TEN stability and localization
@nl
P2093
P2860
P50
P356
P1476
The ubiquitin ligase Nedd4-1 i ...... TEN stability and localization
@en
P2093
Antje Neeb
Hiroshi Kawabe
P2860
P304
P356
10.1073/PNAS.0803233105
P407
P577
2008-06-24T00:00:00Z