The interaction of TIGIT with PVR and PVRL2 inhibits human NK cell cytotoxicity - Wikidata - thesis-toulmin - TriplyDB

The interaction of TIGIT with PVR and PVRL2 inhibits human NK cell cytotoxicity

The interaction of TIGIT with PVR and PVRL2 inhibits human NK cell cytotoxicity

http://www.wikidata.org/entity/Q24651041

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Nectin-2 is a potential target for antibody therapy of breast and ovarian cancers Targeting NK Cells for Anticancer Immunotherapy: Clinical and Preclinical Approaches Beyond CTLA-4 and PD-1, the Generation Z of Negative Checkpoint Regulators Natural killer cells and neuroblastoma: tumor recognition, escape mechanisms, and possible novel immunotherapeutic approaches The role of natural cytotoxicity receptors in various pathologies: emphasis on type I diabetes TIGIT Marks Exhausted T Cells, Correlates with Disease Progression, and Serves as a Target for Immune Restoration in HIV and SIV Infection Increased CD112 expression in methylcholanthrene-induced tumors in CD155-deficient mice Structure of Nectin-2 reveals determinants of homophilic and heterophilic interactions that control cell-cell adhesion Structure of TIGIT immunoreceptor bound to poliovirus receptor reveals a cell-cell adhesion and signaling mechanism that requires cis-trans receptor clustering Vstm3 is a member of the CD28 family and an important modulator of T-cell function The receptors CD96 and CD226 oppose each other in the regulation of natural killer cell functions Cytotoxicity of CD56(bright) NK cells towards autologous activated CD4+ T cells is mediated through NKG2D, LFA-1 and TRAIL and dampened via CD94/NKG2A TIGIT and CD96: new checkpoint receptor targets for cancer immunotherapy.Recognition of nectin-2 by the natural killer cell receptor T cell immunoglobulin and ITIM domain (TIGIT).DNAM-1 control of natural killer cells functions through nectin and nectin-like proteins.Cancer immunotherapy by targeting immune checkpoints: mechanism of T cell dysfunction in cancer immunity and new therapeutic targets.T-cell immunoglobulin and ITIM domain (TIGIT) receptor/poliovirus receptor (PVR) ligand engagement suppresses interferon-γ production of natural killer cells via β-arrestin 2-mediated negative signaling NK cells and multiple myeloma-associated endothelial cells: molecular interactions and influence of IL-27 New Cancer Immunotherapy Agents in Development: a report from an associated program of the 31stAnnual Meeting of the Society for Immunotherapy of Cancer, 2016 Binding of the Fap2 protein of Fusobacterium nucleatum to human inhibitory receptor TIGIT protects tumors from immune cell attack.Balancing natural killer cell activation through paired receptors.TIGIT and PD-1 impair tumor antigen-specific CD8⁺ T cells in melanoma patients.The class-specific BCR tonic signal modulates lymphomagenesis in a c-myc deregulation transgenic model.Activating signals dominate inhibitory signals in CD137L/IL-15 activated natural killer cells.Cell surface signaling molecules in the control of immune responses: a tide model.Nitric oxide donors increase PVR/CD155 DNAM-1 ligand expression in multiple myeloma cells: role of DNA damage response activation.The TIGIT/CD226 axis regulates human T cell function The Role of T Cell Costimulation via DNAM-1 in Kidney Transplantation.Type 1 diabetes vaccine candidates promote human Foxp3(+)Treg induction in humanized mice.TIGIT predominantly regulates the immune response via regulatory T cells.HER2-specific immunoligands engaging NKp30 or NKp80 trigger NK-cell-mediated lysis of tumor cells and enhance antibody-dependent cell-mediated cytotoxicity Cellular Adjuvant Properties, Direct Cytotoxicity of Re-differentiated Vα24 Invariant NKT-like Cells from Human Induced Pluripotent Stem Cells.Recruitment of Grb2 and SHIP1 by the ITT-like motif of TIGIT suppresses granule polarization and cytotoxicity of NK cells.TIGIT-positive circulating follicular helper T cells display robust B-cell help functions: potential role in sickle cell alloimmunization.Costimulatory and Coinhibitory Receptor Pathways in Infectious Disease Impaired NK-mediated regulation of T-cell activity in multiple sclerosis is reconstituted by IL-2 receptor modulation Inflammatory monocytes and NK cells play a crucial role in DNAM-1-dependent control of cytomegalovirus infection.The CD226/CD155 interaction regulates the proinflammatory (Th1/Th17)/anti-inflammatory (Th2) balance in humans.PILRα binds an unknown receptor expressed primarily on CD56bright and decidual-NK cells and activates NK cell functions Profiling the dynamic expression of checkpoint molecules on cytokine-induced killer cells from non-small-cell lung cancer patients.

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The interaction of TIGIT with PVR and PVRL2 inhibits human NK cell cytotoxicity

http://www.wikidata.org/entity/Q24651041

description

2009 nî lūn-bûn

@nan

2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

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name

The interaction of TIGIT with PVR and PVRL2 inhibits human NK cell cytotoxicity

@ast

The interaction of TIGIT with PVR and PVRL2 inhibits human NK cell cytotoxicity

@en

The interaction of TIGIT with PVR and PVRL2 inhibits human NK cell cytotoxicity

@nl

type

label

The interaction of TIGIT with PVR and PVRL2 inhibits human NK cell cytotoxicity

@ast

The interaction of TIGIT with PVR and PVRL2 inhibits human NK cell cytotoxicity

@en

The interaction of TIGIT with PVR and PVRL2 inhibits human NK cell cytotoxicity

@nl

prefLabel

The interaction of TIGIT with PVR and PVRL2 inhibits human NK cell cytotoxicity

@ast

The interaction of TIGIT with PVR and PVRL2 inhibits human NK cell cytotoxicity

@en

The interaction of TIGIT with PVR and PVRL2 inhibits human NK cell cytotoxicity

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Proceedings of the National Academy of Sciences of the United States of America

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The interaction of TIGIT with PVR and PVRL2 inhibits human NK cell cytotoxicity

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Amir Toporik

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Amit Novik

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Hagit Achdout

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Hrvoje Simic

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Liat Dassa

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Meirav Beiman

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Noa Stanietsky

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Ofer Levy

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Ofer Mandelboim

http://www.w3.org/2001/XMLSchema#string

Pinhas Tsukerman

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P2860

Molecular and functional characterization of IRp60, a member of the immunoglobulin superfamily that functions as an inhibitory receptor in human NK cells

The human leukocyte antigen (HLA)-C-specific "activatory" or "inhibitory" natural killer cell receptors display highly homologous extracellular domains but differ in their transmembrane and intracytoplasmic portions

Cloning of B7-2: a CTLA-4 counter-receptor that costimulates human T cell proliferation

Identification of PVR (CD155) and Nectin-2 (CD112) as cell surface ligands for the human DNAM-1 (CD226) activating molecule

The surface protein TIGIT suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells

CD155/PVR plays a key role in cell motility during tumor cell invasion and migration

The role of NK cell recognition of nectin and nectin-like proteins in tumor immunosurveillance

Paired immunoglobulin-like receptor B (PIR-B) inhibits BCR-induced activation of Syk and Btk by SHP-1

Lymphocyte activation via NKG2D: towards a new paradigm in immune recognition?

The requirement for DNAM-1, NKG2D, and NKp46 in the natural killer cell-mediated killing of myeloma cells

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Jurica Arapovic

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