Identification of a serotonin/glutamate receptor complex implicated in psychosis
about
GPCR oligomers in pharmacology and signalingPharmacology of hallucinations: several mechanisms for one single symptom?Metabotropic glutamate mGlu2 receptor is necessary for the pharmacological and behavioral effects induced by hallucinogenic 5-HT2A receptor agonistsIdentification of three residues essential for 5-hydroxytryptamine 2A-metabotropic glutamate 2 (5-HT2A·mGlu2) receptor heteromerization and its psychoactive behavioral functionHead-twitch response in rodents induced by the hallucinogen 2,5-dimethoxy-4-iodoamphetamine: a comprehensive history, a re-evaluation of mechanisms, and its utility as a model.The HIV antiretroviral drug efavirenz has LSD-like propertiesGroup II metabotropic glutamate receptor agonist ameliorates MK801-induced dysfunction of NMDA receptors via the Akt/GSK-3β pathway in adult rat prefrontal cortexSelective actions of novel allosteric modulators reveal functional heteromers of metabotropic glutamate receptors in the CNSFunctional crosstalk and heteromerization of serotonin 5-HT2A and dopamine D2 receptorsHeteromerization of G protein-coupled receptors: relevance to neurological disorders and neurotherapeutics.Receptor heteromerization and drug discovery.Integrated signaling in heterodimers and receptor mosaics of different types of GPCRs of the forebrain: relevance for schizophreniaAllostery at G protein-coupled receptor homo- and heteromers: uncharted pharmacological landscapesBuilding a new conceptual framework for receptor heteromersActivation of metabotropic glutamate 5 (mGlu5) receptors induces spontaneous excitatory synaptic currents in layer V pyramidal cells of the rat prefrontal cortexActivation of adenosine(1) (A(1)) receptors suppresses head shakes induced by a serotonergic hallucinogen in rats.Epigenetic principles and mechanisms underlying nervous system functions in health and diseaseGroup II Metabotropic Glutamate Receptors as Targets for Novel Antipsychotic DrugsLysergic acid diethylamide: a drug of 'use'?Antidepressive, anxiolytic, and antiaddictive effects of ayahuasca, psilocybin and lysergic acid diethylamide (LSD): a systematic review of clinical trials published in the last 25 yearsBasic Pharmacological and Structural Evidence for Class A G-Protein-Coupled Receptor HeteromerizationTherapeutic Targets for Neurodevelopmental Disorders Emerging from Animal Models with Perinatal Immune ActivationThe role of serotonin 5-HT2A receptors in memory and cognitionEffects of serotonin in the hippocampus: how SSRIs and multimodal antidepressants might regulate pyramidal cell functionPreclinical models of antipsychotic drug action.Positive allosteric modulators of metabotropic glutamate 2 receptors in schizophrenia treatmentComputational approaches for modeling GPCR dimerizationRecent advances in the neuropsychopharmacology of serotonergic hallucinogensEpigenetic Mechanisms of Serotonin Signaling.Membrane-sensitive conformational states of helix 8 in the metabotropic Glu2 receptor, a class C GPCRMetabotropic Glutamate 2/3 Receptors and Epigenetic Modifications in Psychotic Disorders: A ReviewCentral serotonin-2A (5-HT2A) receptor dysfunction in depression and epilepsy: the missing link?Glutamatergic transmission in drug reward: implications for drug addictionA functional selectivity mechanism at the serotonin-2A GPCR involves ligand-dependent conformations of intracellular loop 2Xanthurenic Acid Activates mGlu2/3 Metabotropic Glutamate Receptors and is a Potential Trait Marker for SchizophreniaAdenosine-cannabinoid receptor interactions. Implications for striatal functionExtinction-dependent alterations in corticostriatal mGluR2/3 and mGluR7 receptors following chronic methamphetamine self-administration in ratsIncreased behavioral and neuronal responses to a hallucinogenic drug in PACAP heterozygous mutant mice.mGlu2 Receptor Agonism, but Not Positive Allosteric Modulation, Elicits Rapid Tolerance towards Their Primary Efficacy on Sleep Measures in RatsCrosstalk between GABAB and mGlu1a receptors reveals new insight into GPCR signal integration
P2860
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P2860
Identification of a serotonin/glutamate receptor complex implicated in psychosis
description
2008 nî lūn-bûn
@nan
2008 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մարտին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Identification of a serotonin/glutamate receptor complex implicated in psychosis
@ast
Identification of a serotonin/glutamate receptor complex implicated in psychosis
@en
Identification of a serotonin/glutamate receptor complex implicated in psychosis
@nl
type
label
Identification of a serotonin/glutamate receptor complex implicated in psychosis
@ast
Identification of a serotonin/glutamate receptor complex implicated in psychosis
@en
Identification of a serotonin/glutamate receptor complex implicated in psychosis
@nl
prefLabel
Identification of a serotonin/glutamate receptor complex implicated in psychosis
@ast
Identification of a serotonin/glutamate receptor complex implicated in psychosis
@en
Identification of a serotonin/glutamate receptor complex implicated in psychosis
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
Identification of a serotonin/glutamate receptor complex implicated in psychosis
@en
P2093
Graeme Milligan
Javier González-Maeso
Jay A Gingrich
Juan F López-Giménez
Mingming Zhou
Noelia V Weisstaub
Pokman Chan
Rosalind L Ang
Yuuya Okawa
P2860
P2888
P3181
P356
10.1038/NATURE06612
P407
P577
2008-02-24T00:00:00Z
P5875
P6179
1040502270