A functional selectivity mechanism at the serotonin-2A GPCR involves ligand-dependent conformations of intracellular loop 2
about
The pathway of ligand entry from the membrane bilayer to a lipid G protein-coupled receptor.Membrane-Mediated Oligomerization of G Protein Coupled Receptors and Its Implications for GPCR FunctionThe role of experimental and computational structural approaches in 7TM drug discovery.Quantifying conformational changes in GPCRs: glimpse of a common functional mechanism.Computational approaches to detect allosteric pathways in transmembrane molecular machines.Cholesterol-dependent Conformational Plasticity in GPCR Dimers.The Allostery Landscape: Quantifying Thermodynamic Couplings in Biomolecular Systems.Recent Advances and Applications of Molecular Docking to G Protein-Coupled Receptors.Analysis of positive and negative allosteric modulation in metabotropic glutamate receptors 4 and 5 with a dual ligand.Crystal Structure of an LSD-Bound Human Serotonin Receptor.Investigating Small-Molecule Ligand Binding to G Protein-Coupled Receptors with Biased or Unbiased Molecular Dynamics Simulations.Biased signalling: from simple switches to allosteric microprocessors.Molecular mechanisms of allosteric probe dependence in μ opioid receptor.Opportunities and Challenges in the Discovery of Allosteric Modulators of GPCRs.Structural basis for the cooperative allosteric activation of the free fatty acid receptor GPR40.Structural modeling defines transmembrane residues in ADAM17 that are crucial for Rhbdf2-ADAM17-dependent proteolysis.Gs- versus Golf-dependent functional selectivity mediated by the dopamine D1 receptor.Neuroendocrine Associations Underlying the Persistent Therapeutic Effects of Classic Serotonergic Psychedelics.
P2860
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P2860
A functional selectivity mechanism at the serotonin-2A GPCR involves ligand-dependent conformations of intracellular loop 2
description
2014 nî lūn-bûn
@nan
2014 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
name
A functional selectivity mecha ...... ations of intracellular loop 2
@ast
A functional selectivity mecha ...... ations of intracellular loop 2
@en
A functional selectivity mecha ...... ations of intracellular loop 2
@nl
type
label
A functional selectivity mecha ...... ations of intracellular loop 2
@ast
A functional selectivity mecha ...... ations of intracellular loop 2
@en
A functional selectivity mecha ...... ations of intracellular loop 2
@nl
prefLabel
A functional selectivity mecha ...... ations of intracellular loop 2
@ast
A functional selectivity mecha ...... ations of intracellular loop 2
@en
A functional selectivity mecha ...... ations of intracellular loop 2
@nl
P2093
P2860
P921
P3181
P356
P1476
A functional selectivity mecha ...... ations of intracellular loop 2
@en
P2093
George Khelashvili
Jose Manuel Perez-Aguilar
Jufang Shan
P2860
P304
16044-16054
P3181
P356
10.1021/JA508394X
P407
P577
2014-10-31T00:00:00Z