Physical and functional interactions of Galphaq with Rho and its exchange factors - Wikidata - thesis-toulmin - TriplyDB

Physical and functional interactions of Galphaq with Rho and its exchange factors

Physical and functional interactions of Galphaq with Rho and its exchange factors

http://www.wikidata.org/entity/Q24669784

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Mutation of an N-terminal acidic-rich region of p115-RhoGEF dissociates alpha13 binding and alpha13-promoted plasma membrane recruitment Association of Lbc Rho guanine nucleotide exchange factor with alpha-catenin-related protein, alpha-catulin/CTNNAL1, supports serum response factor activation Characterization of G alpha 13-dependent plasma membrane recruitment of p115RhoGEF Akt-mediated cardiomyocyte survival pathways are compromised by G alpha q-induced phosphoinositide 4,5-bisphosphate depletion Focal adhesion kinase as a RhoA-activable signaling scaffold mediating Akt activation and cardiomyocyte protection The Rho guanine nucleotide exchange factor AKAP13 (BRX) is essential for cardiac development in mice Strike a pose: Gαq complexes at the membrane Rho-family GTPases modulate Ca(2+) -dependent ATP release from astrocytes.Structure and function of heterotrimeric G protein-regulated Rho guanine nucleotide exchange factors.PLCε, PKD1, and SSH1L transduce RhoA signaling to protect mitochondria from oxidative stress in the heart.Induction of the matricellular protein CCN1 through RhoA and MRTF-A contributes to ischemic cardioprotection.The Lbc Rho guanine nucleotide exchange factor α-catulin axis functions in serotonin-induced vascular smooth muscle cell mitogenesis and RhoA/ROCK activation.Cellular and molecular action of the mitogenic protein-deamidating toxin from Pasteurella multocida.Pasteurella multocida toxin interaction with host cells: entry and cellular effects.Pasteurella multocida toxin as a tool for studying Gq signal transduction.Gastrin-stimulated Gα13 Activation of Rgnef Protein (ArhGEF28) in DLD-1 Colon Carcinoma Cells.A genome-wide RNAi screen reveals a Trio-regulated Rho GTPase circuitry transducing mitogenic signals initiated by G protein-coupled receptors.The C3 domain of Pasteurella multocida toxin is the minimal domain responsible for activation of Gq-dependent calcium and mitogenic signaling.Selective Membrane Redistribution and Depletion of Gαq-Protein by Pasteurella multocida Toxin Regulation and physiological functions of G12/13-mediated signaling pathways.P2Y5 is a G(alpha)i, G(alpha)12/13 G protein-coupled receptor activated by lysophosphatidic acid that reduces intestinal cell adhesion.Regulation of smooth muscle contraction by small GTPases.Recent insights into Pasteurella multocida toxin and other G-protein-modulating bacterial toxins.ESCRT machinery potentiates HIV-1 utilization of the PI(4,5)P(2)-PLC-IP3R-Ca(2+) signaling cascade.Low concentration of ethanol induce apoptosis in HepG2 cells: role of various signal transduction pathways Rho/ROCK-dependent inhibition of 3T3-L1 adipogenesis by G-protein-deamidating dermonecrotic toxins: differential regulation of Notch1, Pref1/Dlk1, and β-catenin signaling.Activated Galphaq family members induce Rho GTPase activation and Rho-dependent actin filament assembly.Substance P receptor antagonism: a potential novel treatment option for viral-myocarditis RhoA protects the mouse heart against ischemia/reperfusion injury Activation of protein kinase D by signaling through Rho and the alpha subunit of the heterotrimeric G protein G13.Galpha11 induces caspase-mediated proteolytic activation of Rho-associated kinase, ROCK-I, in HeLa cells.Mechanisms of regulation of phospholipase D1 and D2 by the heterotrimeric G proteins G13 and Gq.Cooperation of Gq, Gi, and G12/13 in protein kinase D activation and phosphorylation induced by lysophosphatidic acid.Selective coupling of the S1P3 receptor subtype to S1P-mediated RhoA activation and cardioprotection.RhoA/Rho kinase up-regulate Bax to activate a mitochondrial death pathway and induce cardiomyocyte apoptosis.Inactivation of the calcium sensing receptor inhibits E-cadherin-mediated cell-cell adhesion and calcium-induced differentiation in human epidermal keratinocytes.A Gα12-specific Binding Domain in AKAP-Lbc and p114RhoGEF.

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Physical and functional interactions of Galphaq with Rho and its exchange factors

http://www.wikidata.org/entity/Q24669784

description

2001 nî lūn-bûn

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2001 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2001 թվականի մայիսին հրատարակված գիտական հոդված

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2001年の論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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2001年论文

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name

Physical and functional interactions of Galphaq with Rho and its exchange factors

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Physical and functional interactions of Galphaq with Rho and its exchange factors

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Physical and functional interactions of Galphaq with Rho and its exchange factors

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type

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Physical and functional interactions of Galphaq with Rho and its exchange factors

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Physical and functional interactions of Galphaq with Rho and its exchange factors

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Physical and functional interactions of Galphaq with Rho and its exchange factors

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Physical and functional interactions of Galphaq with Rho and its exchange factors

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Physical and functional interactions of Galphaq with Rho and its exchange factors

@en

Physical and functional interactions of Galphaq with Rho and its exchange factors

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P1433

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P1433

Journal of Biological Chemistry

P1476

Physical and functional interactions of Galphaq with Rho and its exchange factors

@en

P2093

B A Wilson

http://www.w3.org/2001/XMLSchema#string

D Toksoz

http://www.w3.org/2001/XMLSchema#string

J H Brown

http://www.w3.org/2001/XMLSchema#string

M Kobiashvili

http://www.w3.org/2001/XMLSchema#string

S A Sagi

http://www.w3.org/2001/XMLSchema#string

T M Seasholtz

http://www.w3.org/2001/XMLSchema#string

P2860

A novel PDZ domain containing guanine nucleotide exchange factor links heterotrimeric G proteins to Rho

Expression of catalytically inactive phospholipase Cbeta disrupts phospholipase Cbeta and mitogen-activated protein kinase signaling and inhibits small cell lung cancer growth

Activation of the Lbc Rho exchange factor proto-oncogene by truncation of an extended C terminus that regulates transformation and targeting

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

Identification of a putative target for Rho as the serine-threonine kinase protein kinase N

p115 RhoGEF, a GTPase activating protein for Galpha12 and Galpha13

Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13

The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF

Isolation of a NCK-associated kinase, PRK2, an SH3-binding protein and potential effector of Rho protein signaling

Rho GTPases and their effector proteins

P304

15445-52

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scholarly article

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4380800

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P356

10.1074/JBC.M008961200

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P407

P433

18

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276

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2001-05-04T00:00:00Z

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11278452

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P932

1761691

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