Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13 - Wikidata - thesis-toulmin - TriplyDB

Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13

Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13

http://www.wikidata.org/entity/Q28274727

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A G protein gamma subunit-like domain shared between RGS11 and other RGS proteins specifies binding to Gbeta5 subunits A novel PDZ domain containing guanine nucleotide exchange factor links heterotrimeric G proteins to Rho The TSC1 tumour suppressor hamartin regulates cell adhesion through ERM proteins and the GTPase Rho Direct interaction of insulin-like growth factor-1 receptor with leukemia-associated RhoGEF Physical and functional interactions of the lysophosphatidic acid receptors with PDZ domain-containing Rho guanine nucleotide exchange factors (RhoGEFs)Mutation of an N-terminal acidic-rich region of p115-RhoGEF dissociates alpha13 binding and alpha13-promoted plasma membrane recruitment A mammalian Rho-specific guanine-nucleotide exchange factor (p164-RhoGEF) without a pleckstrin homology domain A bacterial effector targets host DH-PH domain RhoGEFs and antagonizes macrophage phagocytosis The tandem BRCT domains of Ect2 are required for both negative and positive regulation of Ect2 in cytokinesis PRR5L degradation promotes mTORC2-mediated PKC-δ phosphorylation and cell migration downstream of Gα12 CIN85 associates with multiple effectors controlling intracellular trafficking of epidermal growth factor receptors Characterization of G alpha 13-dependent plasma membrane recruitment of p115RhoGEF RGS14 is a novel Rap effector that preferentially regulates the GTPase activity of galphao Stimulation of phospholipase C-beta2 by the Rho GTPases Cdc42Hs and Rac1.Leukotriene D4 induces association of active RhoA with phospholipase C-gamma1 in intestinal epithelial cells Galpha 12 activates Rho GTPase through tyrosine-phosphorylated leukemia-associated RhoGEF.Interaction of Galpha 12 and Galpha 13 with the cytoplasmic domain of cadherin provides a mechanism for beta -catenin release Oligomerization of DH domain is essential for Dbl-induced transformation Identification of a novel sequence in PDZ-RhoGEF that mediates interaction with the actin cytoskeleton Galpha12/13 regulate epiboly by inhibiting E-cadherin activity and modulating the actin cytoskeleton Fidelity of G protein beta-subunit association by the G protein gamma-subunit-like domains of RGS6, RGS7, and RGS11 Galphaq directly activates p63RhoGEF and Trio via a conserved extension of the Dbl homology-associated pleckstrin homology domain Physical and functional interactions of Galphaq with Rho and its exchange factors Identification of a gene at 11q23 encoding a guanine nucleotide exchange factor: evidence for its fusion with MLL in acute myeloid leukemia Identification of tetratricopeptide repeat 1 as an adaptor protein that interacts with heterotrimeric G proteins and the small GTPase Ras Expansion of signal transduction by G proteins. The second 15 years or so: from 3 to 16 alpha subunits plus betagamma dimers The GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunits Small GTP-binding protein Rho-mediated signaling promotes proliferation of rheumatoid synovial fibroblasts Phosphorylation-mediated regulation of GEFs for RhoA Cellular mechanisms of the 5-HT7 receptor-mediated signaling S1PR2 links germinal center confinement and growth regulation Rho GTPases at the crossroad of signaling networks in mammals: impact of Rho-GTPases on microtubule organization and dynamics Signal activation and inactivation by the Gα helical domain: a long-neglected partner in G protein signaling Activated RhoA Binds to the Pleckstrin Homology (PH) Domain of PDZ-RhoGEF, a Potential Site for Autoregulation Identification of Critical Residues in G 13 for Stimulation of p115RhoGEF Activity and the Structure of the G 13-p115RhoGEF Regulator of G Protein Signaling Homology (RH) Domain Complex Ras superfamily GEFs and GAPs: validated and tractable targets for cancer therapy?Cdc42: An essential Rho-type GTPase controlling eukaryotic cell polarity.AKAP-Lbc anchors protein kinase A and nucleates Galpha 12-selective Rho-mediated stress fiber formation Leukemia-associated Rho guanine nucleotide exchange factor (LARG) links heterotrimeric G proteins of the G(12) family to Rho Functions of a rho-specific guanine nucleotide exchange factor in neurite retraction. Possible role of a proline-rich motif of KIAA0380 in localization

P2860

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P2860

Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13

http://www.wikidata.org/entity/Q28274727

description

1998 nî lūn-bûn

@nan

1998 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

1998 թվականի հունիսին հրատարակված գիտական հոդված

@hy

1998年の論文

@ja

1998年論文

@yue

1998年論文

@zh-hant

1998年論文

@zh-hk

1998年論文

@zh-mo

1998年論文

@zh-tw

1998年论文

@wuu

name

Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13

@ast

Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13

@en

Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13

@nl

type

label

Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13

@ast

Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13

@en

Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13

@nl

prefLabel

Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13

@ast

Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13

@en

Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13

@nl

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SCIENCE.280.5372.2112

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Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13

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P2093

A G Gilman

http://www.w3.org/2001/XMLSchema#string

G Bollag

http://www.w3.org/2001/XMLSchema#string

M J Hart

http://www.w3.org/2001/XMLSchema#string

P C Sternweis

http://www.w3.org/2001/XMLSchema#string

T Kozasa

http://www.w3.org/2001/XMLSchema#string

W D Singer

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W Roscoe

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X Jiang

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2112-4

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scholarly article

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1817915

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10.1126/SCIENCE.280.5372.2112

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5372

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280

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1998-06-26T00:00:00Z

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9641916

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