The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells - Wikidata - thesis-toulmin - TriplyDB

The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells

The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells

http://www.wikidata.org/entity/Q24670343

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The NF-κB Pathway and Cancer Stem Cells Redox Regulation in Cancer Stem Cells Increased Oxidative Stress as a Selective Anticancer Therapy Reactive oxygen species in cancer stem cells Cancer cells with irons in the fire Targeting JAK2 in the therapy of myeloproliferative neoplasms Concise review: Leukemia stem cells in personalized medicine Quantitative phenotyping-based in vivo chemical screening in a zebrafish model of leukemia stem cell xenotransplantation Update on acute myeloid leukemia stem cells: New discoveries and therapeutic opportunities Telomerase inhibition targets clonogenic multiple myeloma cells through telomere length-dependent and independent mechanisms Cancer stem cells in solid tumours: accumulating evidence and unresolved questions NF-kappaB and IKK as therapeutic targets in cancer Rational Design of a Parthenolide-based Drug Regimen That Selectively Eradicates Acute Myelogenous Leukemia Stem Cells Small molecule antagonists of the Wnt/β-catenin signaling pathway target breast tumor-initiating cells in a Her2/Neu mouse model of breast cancer Anti-cancer activity of a novel small molecule compound that simultaneously activates p53 and inhibits NF-κB signaling Terpenoids and their biosynthesis in cyanobacteria Chemical biology. A small-molecule inhibitor of the aberrant transcription factor CBFβ-SMMHC delays leukemia in mice.Selective leukemic-cell killing by a novel functional class of thalidomide analogs Modulation of cell surface protein free thiols: a potential novel mechanism of action of the sesquiterpene lactone parthenolide Discovery of agents that eradicate leukemia stem cells using an in silico screen of public gene expression data.Curcumin inhibits the side population (SP) phenotype of the rat C6 glioma cell line: towards targeting of cancer stem cells with phytochemicals.Niche-based screening identifies small-molecule inhibitors of leukemia stem cells Independent component analysis: mining microarray data for fundamental human gene expression modules Metabolism and the leukemic stem cell.The increasing complexity of the cancer stem cell paradigm Association of a leukemic stem cell gene expression signature with clinical outcomes in acute myeloid leukemia.Antineoplastic effects of CPPTL via the ROS/JNK pathway in acute myeloid leukemia.Heterocyclic aminoparthenolide derivatives modulate G(2)-M cell cycle progression during Xenopus oocyte maturation.Chronic inflammation and cancer: potential chemoprevention through nuclear factor kappa B and p53 mutual antagonism Flavaglines target primitive leukemia cells and enhance anti-leukemia drug activity.The NF (Nuclear factor)-κB inhibitor parthenolide interacts with histone deacetylase inhibitors to induce MKK7/JNK1-dependent apoptosis in human acute myeloid leukaemia cells.Heck products of parthenolide and melampomagnolide-B as anticancer modulators that modify cell cycle progression Identification and targeting leukemia stem cells: The path to the cure for acute myeloid leukemia.Targeting the osteosarcoma cancer stem cell Enhancement of parthenolide-induced apoptosis by a PKC-alpha inhibition through heme oxygenase-1 blockage in cholangiocarcinoma cells.Reactive oxygen species in normal and tumor stem cells.Targeting breast cancer stem cells.An orally bioavailable parthenolide analog selectively eradicates acute myelogenous leukemia stem and progenitor cells.Evaluation of nuclear factor κB and chemokine receptor CXCR4 co-expression in patients with prostate cancer in the Radiation Therapy Oncology Group (RTOG) 8610 New strategies in acute myelogenous leukemia: leukemogenesis and personalized medicine.

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The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells

http://www.wikidata.org/entity/Q24670343

description

2005 nî lūn-bûn

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2005 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2005 թվականի հունիսին հրատարակված գիտական հոդված

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2005年の論文

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年學術文章

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name

The sesquiterpene lactone part ...... emia stem and progenitor cells

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The sesquiterpene lactone part ...... emia stem and progenitor cells

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The sesquiterpene lactone part ...... emia stem and progenitor cells

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The sesquiterpene lactone part ...... emia stem and progenitor cells

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The sesquiterpene lactone part ...... emia stem and progenitor cells

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The sesquiterpene lactone part ...... emia stem and progenitor cells

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The sesquiterpene lactone part ...... emia stem and progenitor cells

@en

P2093

Craig T Jordan

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Derick R Peterson

http://www.w3.org/2001/XMLSchema#string

Dianna S Howard

http://www.w3.org/2001/XMLSchema#string

Lilliana Karnischky

http://www.w3.org/2001/XMLSchema#string

Monica L Guzman

http://www.w3.org/2001/XMLSchema#string

Randall M Rossi

http://www.w3.org/2001/XMLSchema#string

Xiaojie Li

http://www.w3.org/2001/XMLSchema#string

P2860

Suppressed NF-kB and sustained JNK activation contribute to the sensitization effect of parthenolide to TNF-a induced apoptosis in human cancer cells

Chemopreventive activity of parthenolide against UVB-induced skin cancer and its mechanisms

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

A cell initiating human acute myeloid leukaemia after transplantation into SCID mice

The interleukin-3 receptor alpha chain is a unique marker for human acute myelogenous leukemia stem cells

Detection, isolation, and stimulation of quiescent primitive leukemic progenitor cells from patients with acute myeloid leukemia (AML).

15-Deoxy-Delta(12,14)-prostaglandin J(2): the endogenous electrophile that induces neuronal apoptosis.

Preferential induction of apoptosis for primary human leukemic stem cells.

The antiinflammatory sesquiterpene lactone parthenolide inhibits NF-kappa B by targeting the I kappa B kinase complex.

Cysteine 38 in p65/NF-kappaB plays a crucial role in DNA binding inhibition by sesquiterpene lactones.

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15687234

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apoptotic process

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1895029

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