Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription
about
The mechanism of release of P-TEFb and HEXIM1 from the 7SK snRNP by viral and cellular activators includes a conformational change in 7SKBrd4 coactivates transcriptional activation of NF-kappaB via specific binding to acetylated RelAAcetylation of cyclin T1 regulates the equilibrium between active and inactive P-TEFb in cellsThe Drosophila 7SK snRNP and the essential role of dHEXIM in developmentGene bookmarking accelerates the kinetics of post-mitotic transcriptional re-activation7SK snRNA: a noncoding RNA that plays a major role in regulating eukaryotic transcriptionEpigenetic control of HIV-1 post integration latency: implications for therapyImpact of Chromatin on HIV ReplicationManipulation of the host protein acetylation network by human immunodeficiency virus type 1Bromodomain proteins in HIV infectionTranscriptional control of HIV latency: cellular signaling pathways, epigenetics, happenstance and the hope for a cureChromatin targeting drugs in cancer and immunityStructures of the Dual Bromodomains of the P-TEFb-activating Protein Brd4 at Atomic ResolutionThe super elongation complex (SEC) and MLL in development and disease.The Bromodomain and Extra-Terminal Domain (BET) Family: Functional Anatomy of BET Paralogous ProteinsAcetyl-lysine erasers and readers in the control of pulmonary hypertension and right ventricular hypertrophyBRD4 is an atypical kinase that phosphorylates serine2 of the RNA polymerase II carboxy-terminal domainTargeting bromodomains: epigenetic readers of lysine acetylationBrd4 activates P-TEFb for RNA polymerase II CTD phosphorylationThe mechanisms behind the therapeutic activity of BET bromodomain inhibitionBET bromodomain inhibition as a therapeutic strategy to target c-MycTargeting BET bromodomains for cancer treatmentCracking the control of RNA polymerase II elongation by 7SK snRNP and P-TEFbBrd4 associates with mitotic chromosomes throughout early zebrafish embryogenesisActivation of JNK triggers release of Brd4 from mitotic chromosomes and mediates protection from drug-induced mitotic stressPhosphorylation of CDK9 at Ser175 enhances HIV transcription and is a marker of activated P-TEFb in CD4(+) T lymphocytesThe testis-specific double bromodomain-containing protein BRDT forms a complex with multiple spliceosome components and is required for mRNA splicing and 3'-UTR truncation in round spermatidsBRD4 short isoform interacts with RRP1B, SIPA1 and components of the LINC complex at the inner face of the nuclear membraneAn Epigenetic Compound Library Screen Identifies BET Inhibitors That Promote HSV-1 and -2 Replication by Bridging P-TEFb to Viral Gene Promoters through BRD4Bromodomain-dependent stage-specific male genome programming by BrdtRegistered report: BET bromodomain inhibition as a therapeutic strategy to target c-MycControl of embryonic stem cell identity by BRD4-dependent transcriptional elongation of super-enhancer-associated pluripotency genesDrug Discovery Targeting Bromodomain-Containing Protein 4.Maintenance of muscle myosin levels in adult C. elegans requires both the double bromodomain protein BET-1 and sumoylationIdentification of the P-TEFb complex-interacting domain of Brd4 as an inhibitor of HIV-1 replication by functional cDNA library screening in MT-4 cells.Abrogation of the Brd4-positive transcription elongation factor B complex by papillomavirus E2 protein contributes to viral oncogene repressionDiscovery and characterization of super-enhancer-associated dependencies in diffuse large B cell lymphoma.Papillomavirus interaction with cellular chromatin.Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function.The Role of Bromodomain Testis-Specific Factor, BRDT, in Cancer: A Biomarker and A Possible Therapeutic Target.
P2860
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P2860
Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription
description
2007 nî lūn-bûn
@nan
2007 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription
@ast
Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription
@en
Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription
@nl
type
label
Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription
@ast
Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription
@en
Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription
@nl
prefLabel
Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription
@ast
Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription
@en
Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription
@nl
P2093
P2860
P3181
P356
P1476
Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription
@en
P2093
Dwayne A Bisgrove
Peter Henklein
Tokameh Mahmoudi
P2860
P304
P3181
P356
10.1073/PNAS.0705053104
P407
P50
P577
2007-08-21T00:00:00Z