The testis-specific double bromodomain-containing protein BRDT forms a complex with multiple spliceosome components and is required for mRNA splicing and 3'-UTR truncation in round spermatids
about
The presence, role and clinical use of spermatozoal RNAsThe Bromodomain and Extra-Terminal Domain (BET) Family: Functional Anatomy of BET Paralogous ProteinsBromodomain-dependent stage-specific male genome programming by BrdtThe C-terminal domain of Brd2 is important for chromatin interaction and regulation of transcription and alternative splicing.tBRD-1 and tBRD-2 regulate expression of genes necessary for spermatid differentiation.tBRD-1 selectively controls gene activity in the Drosophila testis and interacts with two new members of the bromodomain and extra-terminal (BET) family.Mouse BRWD1 is critical for spermatid postmeiotic transcription and female meiotic chromosome stability.Two bromodomain proteins functionally interact to recapitulate an essential BRDT-like function in Drosophila spermatocytes.Meiotic failure in cyclin A1-deficient mouse spermatocytes triggers apoptosis through intrinsic and extrinsic signaling pathways and 14-3-3 proteinsSevere impairment of male reproductive organ development in a low SMN expressing mouse model of spinal muscular atrophyThe Bromodomain testis-specific gene (Brdt) characterization and expression in gilthead seabream, Sparus aurata, and European seabass, Dicentrarchus labraxThe role of the double bromodomain-containing BET genes during mammalian spermatogenesis.Bromodomains and their pharmacological inhibitors.Targeting TDP-43 in neurodegenerative diseases.Alternative splicing: the pledge, the turn, and the prestige : The key role of alternative splicing in human biological systems.BRD7 plays an anti-inflammatory role during early acute inflammation by inhibiting activation of the NF-кB signaling pathway.BET Protein BRDT Complexes With HDAC1, PRMT5, and TRIM28 and Functions in Transcriptional Repression During Spermatogenesis.Early Histone H4 Acetylation during Chromatin Remodeling in Equine Spermatogenesis.Roles of RNA-binding Proteins and Post-transcriptional Regulation in Driving Male Germ Cell Development in the Mouse.Heritable Sperm Chromatin Epigenetics: A Break to Remember.BRDT is an essential epigenetic regulator for proper chromatin organization, silencing of sex chromosomes and crossover formation in male meiosis.
P2860
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P2860
The testis-specific double bromodomain-containing protein BRDT forms a complex with multiple spliceosome components and is required for mRNA splicing and 3'-UTR truncation in round spermatids
description
2012 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2012
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im August 2012 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
@en
vedecký článok (publikovaný 2012/08/01)
@sk
vědecký článek publikovaný v roce 2012
@cs
wetenschappelijk artikel (gepubliceerd op 2012/08/01)
@nl
наукова стаття, опублікована в серпні 2012
@uk
مقالة علمية (نشرت في أغسطس 2012)
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name
The testis-specific double bro ...... truncation in round spermatids
@ast
The testis-specific double bro ...... truncation in round spermatids
@en
The testis-specific double bro ...... truncation in round spermatids
@nl
type
label
The testis-specific double bro ...... truncation in round spermatids
@ast
The testis-specific double bro ...... truncation in round spermatids
@en
The testis-specific double bro ...... truncation in round spermatids
@nl
prefLabel
The testis-specific double bro ...... truncation in round spermatids
@ast
The testis-specific double bro ...... truncation in round spermatids
@en
The testis-specific double bro ...... truncation in round spermatids
@nl
P2093
P2860
P921
P3181
P356
P1476
The testis-specific double bro ...... truncation in round spermatids
@en
P2093
Binyamin D. Berkovits
Debra J. Wolgemuth
Paolo Guarnieri
P2860
P304
P3181
P356
10.1093/NAR/GKS342
P407
P577
2012-08-01T00:00:00Z