PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor - Wikidata - thesis-toulmin - TriplyDB

PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor

PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor

http://www.wikidata.org/entity/Q24676972

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The notch ligand JAGGED1 as a target for anti-tumor therapy M-Ras/R-Ras3, a transforming ras protein regulated by Sos1, GRF1, and p120 Ras GTPase-activating protein, interacts with the putative Ras effector AF6 Nectin/PRR: an immunoglobulin-like cell adhesion molecule recruited to cadherin-based adherens junctions through interaction with Afadin, a PDZ domain-containing protein Activation of EphA2 kinase suppresses integrin function and causes focal-adhesion-kinase dephosphorylation The neural cell recognition molecule neurofascin interacts with syntenin-1 but not with syntenin-2, both of which reveal self-associating activity Soluble Jagged 1 represses the function of its transmembrane form to induce the formation of the Src-dependent chord-like phenotype c-Src is a PDZ interaction partner and substrate of the E3 ubiquitin ligase Ligand-of-Numb protein X1 Regulation of c-Src by binding to the PDZ domain of AF-6 Inhibition of integrin-mediated cell adhesion but not directional cell migration requires catalytic activity of EphB3 receptor tyrosine kinase. Role of Rho family small GTPases Platelet-derived growth factor receptor association with Na(+)/H(+) exchanger regulatory factor potentiates receptor activity Interactions between Eph kinases and ephrins provide a mechanism to support platelet aggregation once cell-to-cell contact has occurred.PDZ domains: fundamental building blocks in the organization of protein complexes at the plasma membrane Quantitative phosphotyrosine proteomics of EphB2 signaling by stable isotope labeling with amino acids in cell culture (SILAC)Roles of Eph receptors and ephrins in segmental patterning The Bcr kinase downregulates Ras signaling by phosphorylating AF-6 and binding to its PDZ domain Differential regulation of EphA2 in normal and malignant cells Regulation of G protein-coupled receptor function by Na+/H+ exchange regulatory factors Monomeric structure of the human EphB2 sterile alpha motif domain Structure of the sterile alpha motif (SAM) domain of the Saccharomyces cerevisiae mitogen-activated protein kinase pathway-modulating protein STE50 and analysis of its interaction with the STE11 SAM Nectin-3, a new member of immunoglobulin-like cell adhesion molecules that shows homophilic and heterophilic cell-cell adhesion activities Thermodynamic and kinetic characterization of the interaction between the Ras binding domain of AF6 and members of the Ras subfamily Replacing two conserved tyrosines of the EphB2 receptor with glutamic acid prevents binding of SH2 domains without abrogating kinase activity and biological responses A PDZ domain protein interacts with the C-terminal tail of the insulin-like growth factor-1 receptor but not with the insulin receptor The ERBB2/HER2 receptor differentially interacts with ERBIN and PICK1 PSD-95/DLG/ZO-1 domain proteins Signals from Eph and ephrin proteins: a developmental tool kit Distinct binding specificity of the multiple PDZ domains of INADL, a human protein with homology to INAD from Drosophila melanogaster RYK, a catalytically inactive receptor tyrosine kinase, associates with EphB2 and EphB3 but does not interact with AF-6 Astrocytic Ephrin-B1 Regulates Synapse Remodeling Following Traumatic Brain Injury Two cell adhesion molecules, nectin and cadherin, interact through their cytoplasmic domain-associated proteins The junction-associated protein AF-6 interacts and clusters with specific Eph receptor tyrosine kinases at specialized sites of cell-cell contact in the brain Nectin: an adhesion molecule involved in formation of synapses Nectin4/PRR4, a new afadin-associated member of the nectin family that trans-interacts with nectin1/PRR1 through V domain interaction Phosphorylation of tyrosine residues in the kinase domain and juxtamembrane region regulates the biological and catalytic activities of Eph receptors PDZ domain proteins: plug and play!Identification and cloning of xp95, a putative signal transduction protein in Xenopus oocytes.Identifying and Analyzing Novel Epilepsy-Related Genes Using Random Walk with Restart Algorithm.Downregulation of the Ras-mitogen-activated protein kinase pathway by the EphB2 receptor tyrosine kinase is required for ephrin-induced neurite retraction.PICK-1: a scaffold protein that interacts with Nectins and JAMs at cell junctions.Selective regulation of Notch ligands during angiogenesis is mediated by vimentin Growth factor signaling pathways in vascular development.

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PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor

http://www.wikidata.org/entity/Q24676972

description

1998 nî lūn-bûn

@nan

1998 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

1998 թվականի օգոստոսին հրատարակված գիտական հոդված

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1998年の論文

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1998年論文

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1998年論文

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1998年論文

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1998年論文

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1998年論文

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1998年论文

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PDZ-domain-mediated interactio ...... inase activity of the receptor

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Proceedings of the National Academy of Sciences of the United States of America

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PDZ-domain-mediated interactio ...... inase activity of the receptor

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B Böhme

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P2860

Clustering of Shaker-type K+ channels by interaction with a family of membrane-associated guanylate kinases

Characterization of a novel Src-like adapter protein that associates with the Eck receptor tyrosine kinase

Receptor tyrosine kinase specific for the skeletal muscle lineage: expression in embryonic muscle, at the neuromuscular junction, and after injury

PCR mediated detection of a new human receptor-tyrosine-kinase, HEK 2

cDNA cloning and tissue distribution of five human EPH-like receptor protein-tyrosine kinases

Cloning of the ALL-1 fusion partner, the AF-6 gene, involved in acute myeloid leukemias with the t(6;11) chromosome translocation

Ligand activation of ELK receptor tyrosine kinase promotes its association with Grb10 and Grb2 in vascular endothelial cells

Cell-cell adhesion mediated by binding of membrane-anchored ligand LERK-2 to the EPH-related receptor human embryonal kinase 2 promotes tyrosine kinase activity

Neurexins: synaptic cell surface proteins related to the alpha-latrotoxin receptor and laminin

Juxtamembrane tyrosine residues couple the Eph family receptor EphB2/Nuk to specific SH2 domain proteins in neuronal cells

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