about
ROS and ROS-Mediated Cellular SignalingApplication of a new dual localization-affinity purification tag reveals novel aspects of protein kinase biology in Aspergillus nidulansCross-regulation of Phosphodiesterase 1 and Phosphodiesterase 2 Activities Controls Dopamine-mediated Striatal α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor TraffickingMolecular Determinants Underlying Binding Specificities of the ABL Kinase Inhibitors: Combining Alanine Scanning of Binding Hot Spots with Network Analysis of Residue Interactions and CoevolutionStructure-based network analysis of activation mechanisms in the ErbB family of receptor tyrosine kinases: the regulatory spine residues are global mediators of structural stability and allosteric interactions.Uncovering Aberrant Mutant PKA Function with Flow Cytometric FRETMolecular dynamics simulations and modelling of the residue interaction networks in the BRAF kinase complexes with small molecule inhibitors: probing the allosteric effects of ligand-induced kinase dimerization and paradoxical activation.Exploring Molecular Mechanisms of Paradoxical Activation in the BRAF Kinase Dimers: Atomistic Simulations of Conformational Dynamics and Modeling of Allosteric Communication Networks and Signaling Pathways.The Concise Guide to PHARMACOLOGY 2013/14: enzymes.Specific Sirt1 Activator-mediated Improvement in Glucose Homeostasis Requires Sirt1-Independent Activation of AMPK.The Activation of Protein Kinase A by the Calcium-Binding Protein S100A1 Is Independent of Cyclic AMP.A long lasting β1 adrenergic receptor stimulation of cAMP/protein kinase A (PKA) signal in cardiac myocytes.Genetic suppression of β2-adrenergic receptors ameliorates tau pathology in a mouse model of tauopathies.Regulation of mitochondrial poly(ADP-Ribose) polymerase activation by the β-adrenoceptor/cAMP/protein kinase A axis during oxidative stress.Spatial encoding of cyclic AMP signaling specificity by GPCR endocytosisSoluble adenylyl cyclase in health and disease.Altered regulation of protein kinase a activity in the medial prefrontal cortex of normal and brain-injured animals actively engaged in a working memory task.Generation and characterization of ATP analog-specific protein kinase Cδ.Fluorescent biosensors for high throughput screening of protein kinase inhibitors.Mitochondria as signaling organelles.Cyclic AMP signaling reduces sirtuin 6 expression in non-small cell lung cancer cells by promoting ubiquitin-proteasomal degradation via inhibition of the Raf-MEK-ERK (Raf/mitogen-activated extracellular signal-regulated kinase/extracellular signal-PKA-type I selective constrained peptide disruptors of AKAP complexesEndothelial CD99 signals through soluble adenylyl cyclase and PKA to regulate leukocyte transendothelial migration.A-kinase-anchoring proteins coordinate inflammatory responses to cigarette smoke in airway smooth muscle.Defining A-Kinase Anchoring Protein (AKAP) Specificity for the Protein Kinase A Subunit RI (PKA-RI)The A-kinase Anchoring Protein GSKIP Regulates GSK3β Activity and Controls Palatal Shelf Fusion in Mice.Phosphodiesterases and adrenal Cushing in mice and humans.Structure-Activity Relationship Studies of Substituted 2-(Isoxazol-3-yl)-2-oxo-N'-phenyl-acetohydrazonoyl Cyanide Analogues: Identification of Potent Exchange Proteins Directly Activated by cAMP (EPAC) Antagonists.Neuronostatin acts via GPR107 to increase cAMP-independent PKA phosphorylation and proglucagon mRNA accumulation in pancreatic α-cellsModelling intracellular competition for calcium: kinetic and thermodynamic control of different molecular modes of signal decodingStructures of cGMP-Dependent Protein Kinase (PKG) Iα Leucine Zippers Reveal an Interchain Disulfide Bond Important for Dimer Stability.The G protein Gαs acts as a tumor suppressor in sonic hedgehog signaling-driven tumorigenesis.A new autoinhibited kinase conformation reveals a salt-bridge switch in kinase activation.Protein kinase A induces UCP1 expression in specific adipose depots to increase energy expenditure and improve metabolic health.PKA regulatory IIα subunit is essential for PGD2-mediated resolution of inflammation.Activation of mTOR (mechanistic target of rapamycin) in rheumatic diseases.Role of cyclic AMP in the eye with glaucoma.Adenylyl cyclases in the digestive system.cAMP signaling in subcellular compartments.Role of soluble adenylyl cyclase in mitochondria.
P2860
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P2860
description
2013 nî lūn-bûn
@nan
2013 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
PKA: lessons learned after twenty years
@ast
PKA: lessons learned after twenty years
@en
PKA: lessons learned after twenty years
@nl
type
label
PKA: lessons learned after twenty years
@ast
PKA: lessons learned after twenty years
@en
PKA: lessons learned after twenty years
@nl
prefLabel
PKA: lessons learned after twenty years
@ast
PKA: lessons learned after twenty years
@en
PKA: lessons learned after twenty years
@nl
P2093
P2860
P3181
P1476
PKA: lessons learned after twenty years
@en
P2093
Jon M Steichen
Malik M Keshwani
Ping Zhang
Susan S Taylor
P2860
P304
P3181
P356
10.1016/J.BBAPAP.2013.03.007
P407
P577
2013-03-25T00:00:00Z