Structural characterization of nitric oxide synthase isoforms reveals striking active-site conservation - Wikidata - thesis-toulmin - TriplyDB

Structural characterization of nitric oxide synthase isoforms reveals striking active-site conservation

Structural characterization of nitric oxide synthase isoforms reveals striking active-site conservation

http://www.wikidata.org/entity/Q27617498

about

Vitamins C and E: beneficial effects from a mechanistic perspective NO formation by a catalytically self-sufficient bacterial nitric oxide synthase from Sorangium cellulosum Stabilization and characterization of a heme-oxy reaction intermediate in inducible nitric-oxide synthase Proinflammatory role of inducible nitric oxide synthase in acute hyperoxic lung injury Crystal structures of zinc-free and -bound heme domain of human inducible nitric-oxide synthase. Implications for dimer stability and comparison with endothelial nitric-oxide synthase Proton delivery in NO reduction by fungal nitric-oxide reductase. Cryogenic crystallography, spectroscopy, and kinetics of ferric-NO complexes of wild-type and mutant enzymes Allosteric inhibitors of inducible nitric oxide synthase dimerization discovered via combinatorial chemistry Implications for isoform-selective inhibitor design derived from the binding mode of bulky isothioureas to the heme domain of endothelial nitric-oxide synthase Crystal structure of the FAD/NADPH-binding domain of rat neuronal nitric-oxide synthase. Comparisons with NADPH-cytochrome P450 oxidoreductase Structural basis for pterin antagonism in nitric-oxide synthase. Development of novel 4-oxo-pteridine antagonists of (6R)-5,6,7,8-tetrahydrobiopterin Structural basis for the specificity of the nitric-oxide synthase inhibitors W1400 and Nomega-propyl-L-Arg for the inducible and neuronal isoforms Structural characterization and kinetics of nitric-oxide synthase inhibition by novel N5-(iminoalkyl)- and N5-(iminoalkenyl)-ornithines Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase Structure-Based Design and Synthesis of N ω -Nitro- l -Arginine-Containing Peptidomimetics as Selective Inhibitors of Neuronal Nitric Oxide Synthase. Displacement of the Heme Structural Water The tuberculosis prodrug isoniazid bound to activating peroxidases Minimal Pharmacophoric Elements and Fragment Hopping, an Approach Directed at Molecular Diversity and Isozyme Selectivity. Design of Selective Neuronal Nitric Oxide Synthase Inhibitors Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase Exploration of the Active Site of Neuronal Nitric Oxide Synthase by the Design and Synthesis of Pyrrolidinomethyl 2-Aminopyridine Derivatives The Mobility of a Conserved Tyrosine Residue Controls Isoform-Dependent Enzyme–Inhibitor Interactions in Nitric Oxide Synthases Ribosome. The complete structure of the 55S mammalian mitochondrial ribosome Nitric oxide synthases: structure, function and inhibition Role of nitric oxide synthase in the light-induced development of sporangiophores in Phycomyces blakesleeanus Kinetics of CO binding to the haem domain of murine inducible nitric oxide synthase: differential effects of haem domain ligands Selective inhibition of human inducible nitric oxide synthase by S-alkyl-L-isothiocitrulline-containing dipeptides Nitric oxide synthase is induced in sporulation of Physarum polycephalum Telmisartan protects 5/6 Nx rats against renal injury by enhancing nNOS-derived NO generation via regulation of PPARγ signaling Cloning, expression, and characterization of a nitric oxide synthase protein from Deinococcus radiodurans Contrasting effects of N5-substituted tetrahydrobiopterin derivatives on phenylalanine hydroxylase, dihydropteridine reductase and nitric oxide synthase A bridging interaction allows calmodulin to activate NO synthase through a bi-modal mechanism Modulating Vascular Hemodynamics With an Alpha Globin Mimetic Peptide (HbαX).Endothelial nitric oxide synthase in the microcirculation.Insight into protein structure and protein-ligand recognition by Fourier transform infrared spectroscopy.Zinc-binding cysteines: diverse functions and structural motifs.NADPH-cytochrome P450 oxidoreductase: prototypic member of the diflavin reductase family.Mutation of the five conserved histidines in the endothelial nitric-oxide synthase hemoprotein domain. No evidence for a non-heme metal requirement for catalysis.Rapid kinetic studies link tetrahydrobiopterin radical formation to heme-dioxy reduction and arginine hydroxylation in inducible nitric-oxide synthase.Reconstitution of pterin-free inducible nitric-oxide synthase.Tetrahydrobiopterin in cardiovascular health and disease.Peroxynitrite induces destruction of the tetrahydrobiopterin and heme in endothelial nitric oxide synthase: transition from reversible to irreversible enzyme inhibition Structural and mechanistic aspects of flavoproteins: electron transfer through the nitric oxide synthase flavoprotein domain.

P2860

Q24617202-18527A30-39AB-4687-9E7B-5F501070A654 Q24646635-5933D93D-EE42-4CB2-8085-FA6802A7A681 Q24655182-96726DBB-401E-453C-A26F-9800C3FC7F85 Q24796301-D6CE5164-0A73-4BE9-A86D-477FBD1CF5DC Q27619063-405CADB3-389B-44A0-A61D-9F74A592FEF9 Q27621322-5DA379FD-779C-40EF-8776-79AF06FDB4F8 Q27621434-BF248CEE-1C26-4FE5-BBBE-EAE3D2B6A5D7 Q27631560-8387C788-0F22-42C2-91DA-753051D8561E Q27633641-B953267E-A9F1-4264-BDD5-76787E21634E Q27635239-4B90D1D9-B077-443F-A73C-F8349712E420 Q27641955-02792077-0F40-4148-8449-B225EB627F5A Q27641968-9FD13FD4-59A4-4E55-8D16-FB78EF84934A Q27642934-2301E303-9E1A-47ED-BD7B-09B6ACF764E8 Q27644394-8D2FCF72-6B52-4BE2-A71D-7EDAC0FF0B93 Q27649209-FAB61254-9D0B-47B1-A7BB-FF247642737C Q27649995-444D6B4F-966D-46F7-9E98-F233F1C49387 Q27652490-9810451F-EA82-4110-B4D9-40948C8F10B6 Q27665170-25BB987E-FCE3-432C-A7E3-618962487AC6 Q27684931-B563131B-53C5-46CF-9AB0-54ADC9103D02 Q27700074-7A58FA8A-34CC-409A-995A-09CB7562ADDB Q28207668-00C1D2C2-0BBE-4867-90C5-3990E3C9ACFB Q28344263-753B4137-BF1A-42EF-BCFA-AED096DAC89B Q28345236-9E649E4C-08B4-4E17-9E27-B97A142E3013 Q28363098-70297815-77AC-4251-A241-DDB616E018A9 Q28365347-DE806FE8-EB4C-4BF6-9B63-F5BFD2C88323 Q28396739-92AB7A94-B93B-4BE2-923E-86B8A33D8094 Q28485658-F0A9C4DF-3F34-4AF4-9EFC-7E4A526F8880 Q28574134-314E8981-B22D-4226-9095-751234D5133F Q28576068-D779EED6-D0BF-49F1-8F54-9D7D4E6B9551 Q30275542-A0938403-A485-4B34-B9C1-C4404AEA9EC8 Q30278654-AAA7956C-DFAC-4166-9D1B-33377EDB0A29 Q30327608-E9EA7665-4887-4C20-85DD-1F93C3F6223E Q30364031-5E16207F-CFC5-406D-AA49-59C61B4089BD Q30537968-E5594AB9-C3B9-42DB-BF15-147B7B76B021 Q30741770-DC2D72D1-D34B-44BF-8A4D-F336A39253F3 Q31446994-6261A413-FF35-4383-9AE0-A434849EDF9B Q31448893-0C1DECC4-A3FA-4167-996F-DB95FDE0B672 Q33687812-5B17A1B5-855E-463E-AE52-6FAF46D8FED5 Q33775518-3BEDCD84-33C4-43E3-9B06-64B8535CF22D Q33830350-F4AD457C-45D4-4E45-A2A7-31AC4186CD09

P2860

Structural characterization of nitric oxide synthase isoforms reveals striking active-site conservation

http://www.wikidata.org/entity/Q27617498

description

1999 nî lūn-bûn

@nan

1999 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

1999 թվականի մարտին հրատարակված գիտական հոդված

@hy

1999年の論文

@ja

1999年論文

@yue

1999年論文

@zh-hant

1999年論文

@zh-hk

1999年論文

@zh-mo

1999年論文

@zh-tw

1999年论文

@wuu

name

Structural characterization of ...... iking active-site conservation

@ast

Structural characterization of ...... iking active-site conservation

@en

Structural characterization of ...... iking active-site conservation

@nl

type

label

Structural characterization of ...... iking active-site conservation

@ast

Structural characterization of ...... iking active-site conservation

@en

Structural characterization of ...... iking active-site conservation

@nl

prefLabel

Structural characterization of ...... iking active-site conservation

@ast

Structural characterization of ...... iking active-site conservation

@en

Structural characterization of ...... iking active-site conservation

@nl

P1433

Q27617498-93281BEF-7F99-4B27-B1C1-6F1648CCA9BD

P1476

Q27617498-D70C7EA0-8044-4CF1-B2B1-060BAEE2C8FA

P2093

Q27617498-13E43F59-BFE5-496F-8DAF-4639995BBE91

Q27617498-3C394345-6CE2-4913-9C53-34139C93A041

Q27617498-3CFE06EC-D8D4-41BC-8C8A-75C8F21D91CF

Q27617498-412B639F-DA41-45E6-AB6F-2E6F46E2D128

Q27617498-66B2DD46-4AF3-414C-A11D-5B2D3EBEB5DD

Q27617498-7BB5EECA-0441-4817-8976-DD9EEEF8F0A8

Q27617498-8FB580DB-4457-44ED-848C-50AC3E7FD4EC

Q27617498-BC208D97-0462-44A2-8BDB-DD9ECBD07973

Q27617498-C1955765-706E-4B0F-A4F9-5910F4F2DF22

Q27617498-CF83D7E5-C4CD-470D-BAD7-0189A6C7072C

P304

Q27617498-456B9445-9E77-4627-AC23-670C06B7ED50

P31

Q27617498-8A44DC57-4DF7-4710-81EC-7DD813A22C0E

P356

Q27617498-8AD51421-1A3A-4E88-8F52-E83260D1C115

P433

Q27617498-94C4485E-2EE7-407B-A580-81A9A347128C

P478

Q27617498-51DE7768-714E-4DC0-BFF0-11507926260E

P50

Q27617498-DA61A917-3E19-42EA-B220-0989FFB9762F

P577

Q27617498-62C58AA4-341A-449F-8815-28A5FB88EB47

P698

Q27617498-5FD35245-62C2-4277-BF30-2AAD21EA13BD

P356

P1433

Nature structural biology

P1476

Structural characterization of ...... iking active-site conservation

@en

P2093

Dolphin E

http://www.w3.org/2001/XMLSchema#string

Fossetta JD

http://www.w3.org/2001/XMLSchema#string

Hruza A

http://www.w3.org/2001/XMLSchema#string

Lundell DJ

http://www.w3.org/2001/XMLSchema#string

Lunn CA

http://www.w3.org/2001/XMLSchema#string

Narula SK

http://www.w3.org/2001/XMLSchema#string

Niu XD

http://www.w3.org/2001/XMLSchema#string

Prongay AJ

http://www.w3.org/2001/XMLSchema#string

Reichert P

http://www.w3.org/2001/XMLSchema#string

Weber PC

http://www.w3.org/2001/XMLSchema#string

P304

233-242

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/6675

http://www.w3.org/2001/XMLSchema#string

P433

3

http://www.w3.org/2001/XMLSchema#string

P478

6

http://www.w3.org/2001/XMLSchema#string

P50

P577

1999-03-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

10074942

http://www.w3.org/2001/XMLSchema#string