A closer view of the conformation of the Lac repressor bound to operator
about
Predicting deleterious amino acid substitutionsRole of the lytic repressor in prophage induction of phage lambda as analyzed by a module-replacement approachStructural analysis of lac repressor bound to allosteric effectorsAllostery in the LacI/GalR family: variations on a themeTranscription-factor-mediated DNA looping probed by high-resolution, single-molecule imaging in live E. coli cellsNoise contributions in an inducible genetic switch: a whole-cell simulation studyThe structural basis of acyl coenzyme A-dependent regulation of the transcription factor FadRCorepressor-induced organization and assembly of the biotin repressor: A model for allosteric activation of a transcriptional regulatorPlasticity in protein-DNA recognition: lac repressor interacts with its natural operator 01 through alternative conformations of its DNA-binding domain.Structural basis for recognition of the matrix attachment region of DNA by transcription factor SATB1The structures of transcription factor CGL2947 fromCorynebacterium glutamicumin two crystal forms: A novel homodimer assembling and the implication for effector-binding modeA protein functional leap: how a single mutation reverses the function of the transcription regulator TetRInsight into the induction mechanism of the GntR/HutC bacterial transcription regulator YvoAStructures of carbon catabolite protein A-(HPr-Ser46-P) bound to diverse catabolite response element sites reveal the basis for high-affinity binding to degenerate DNA operatorsStructures of the Escherichia coli transcription activator and regulator of diauxie, XylR: an AraC DNA-binding family member with a LacI/GalR ligand-binding domainRheostats and toggle switches for modulating protein functionAmino acid positions subject to multiple coevolutionary constraints can be robustly identified by their eigenvector network centrality scoresStructural dynamics of the lac repressor-DNA complex revealed by a multiscale simulationProtein-induced changes in DNA structure and dynamics observed with noncovalent site-directed spin labeling and PELDOR.AlloRep: A Repository of Sequence, Structural and Mutagenesis Data for the LacI/GalR Transcription RegulatorsData on publications, structural analyses, and queries used to build and utilize the AlloRep database.Structure-based predictive models for allosteric hot spots.ProPhylER: a curated online resource for protein function and structure based on evolutionary constraint analyses.Comparing the functional roles of nonconserved sequence positions in homologous transcription repressors: implications for sequence/function analyses.Protein-induced DNA linking number change by sequence-specific DNA binding proteins and its biological effects.Single-molecule studies of repressor-DNA interactions show long-range interactions.DNA twisting flexibility and the formation of sharply looped protein-DNA complexes.In vivo kinetics of transcription initiation of the lar promoter in Escherichia coli. Evidence for a sequential mechanism with two rate-limiting steps.Operator-bound GalR dimers close DNA loops by direct interaction: tetramerization and inducer binding.Functionally important positions can comprise the majority of a protein's architecture.Radiolysis of lac repressor by gamma-rays and heavy ions: a two-hit model for protein inactivation.Fluorescence resonance energy transfer over approximately 130 basepairs in hyperstable lac repressor-DNA loops.What controls DNA looping?Comparison of deterministic and stochastic models of the lac operon genetic network.Testing computational prediction of missense mutation phenotypes: functional characterization of 204 mutations of human cystathionine beta synthaseInterplay of protein and DNA structure revealed in simulations of the lac operon.Modeling the Lac repressor-operator assembly: the influence of DNA looping on Lac repressor conformation.Environmental dependence of genetic constraint.Multiple co-evolutionary networks are supported by the common tertiary scaffold of the LacI/GalR proteins.Computational modelling and analysis of the molecular network regulating sporulation initiation in Bacillus subtilis
P2860
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P2860
A closer view of the conformation of the Lac repressor bound to operator
description
2000 nî lūn-bûn
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2000 թուականի Մարտին հրատարակուած գիտական յօդուած
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2000 թվականի մարտին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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A closer view of the conformation of the Lac repressor bound to operator
@ast
A closer view of the conformation of the Lac repressor bound to operator
@en
A closer view of the conformation of the Lac repressor bound to operator
@nl
type
label
A closer view of the conformation of the Lac repressor bound to operator
@ast
A closer view of the conformation of the Lac repressor bound to operator
@en
A closer view of the conformation of the Lac repressor bound to operator
@nl
prefLabel
A closer view of the conformation of the Lac repressor bound to operator
@ast
A closer view of the conformation of the Lac repressor bound to operator
@en
A closer view of the conformation of the Lac repressor bound to operator
@nl
P3181
P356
P1476
A closer view of the conformation of the Lac repressor bound to operator
@en
P2093
P304
P3181
P356
10.1038/73317
P577
2000-03-01T00:00:00Z