Backbone Structure of the Amantadine-Blocked Trans-Membrane Domain M2 Proton Channel from Influenza A Virus
about
Magic angle spinning NMR of virusesRecent progress in structure-based anti-influenza drug designM2 protein from influenza A: from multiple structures to biophysical and functional insightsNMR structures of membrane proteins in phospholipid bilayersConformational changes induced by a single amino acid substitution in thetrans-membrane domain of Vpu: Implications for HIV-1 susceptibility to channel blocking drugsStructural basis for the function and inhibition of an influenza virus proton channelStructure of Amantadine-Bound M2 Transmembrane Peptide of Influenza A in Lipid Bilayers from Magic-Angle-Spinning Solid-State NMR: The Role of Ser31 in Amantadine BindingBackbone structure of a small helical integral membrane protein: A unique structural characterizationStructure and topology of monomeric phospholamban in lipid membranes determined by a hybrid solution and solid-state NMR approachStructure of the amantadine binding site of influenza M2 proton channels in lipid bilayersStructure and mechanism of proton transport through the transmembrane tetrameric M2 protein bundle of the influenza A virusInsight into the Mechanism of the Influenza A Proton Channel from a Structure in a Lipid BilayerSupramolecular Structure of Membrane-Associated Polypeptides by Combining Solid-State NMR and Molecular Dynamics SimulationsInfluenza M2 proton channelsThe Influenza M2 Ectodomain Regulates the Conformational Equilibria of the Transmembrane Proton Channel: Insights from Solid-State Nuclear Magnetic ResonanceNMR structures of polytopic integral membrane proteins.Solid state NMR: The essential technology for helical membrane protein structural characterization.Assignment of oriented sample NMR resonances from a three transmembrane helix protein.Cryoprotection of lipid membranes for high-resolution solid-state NMR studies of membrane peptides and proteins at low temperature.Probing membrane protein structure using water polarization transfer solid-state NMR.Survival analysis of infected mice reveals pathogenic variations in the genome of avian H1N1 virusesA refinement protocol to determine structure, topology, and depth of insertion of membrane proteins using hybrid solution and solid-state NMR restraints.Structures of influenza A proteins and insights into antiviral drug targets.Drug sensitivity, drug-resistant mutations, and structures of three conductance domains of viral porins.Membrane protein structure and dynamics from NMR spectroscopy.Paramagnetic Cu(II) for probing membrane protein structure and function: inhibition mechanism of the influenza M2 proton channel.Magic angle spinning and oriented sample solid-state NMR structural restraints combine for influenza a M2 protein functional insights.Glycines: role in α-helical membrane protein structures and a potential indicator of native conformation.Modeling the membrane environment has implications for membrane protein structure and function: influenza A M2 protein.Solid state NMR strategy for characterizing native membrane protein structuresStructural basis for proton conduction and inhibition by the influenza M2 protein.Drug-induced conformational and dynamical changes of the S31N mutant of the influenza M2 proton channel investigated by solid-state NMR.Conformational analysis of the full-length M2 protein of the influenza A virus using solid-state NMR.Solid state NMR and protein-protein interactions in membranesWhy bound amantadine fails to inhibit proton conductance according to simulations of the drug-resistant influenza A M2 (S31N).Solid-state NMR characterization of conformational plasticity within the transmembrane domain of the influenza A M2 proton channel.Free-energy profiles for ions in the influenza M2-TMD channelTilt and azimuthal angles of a transmembrane peptide: a comparison between molecular dynamics calculations and solid-state NMR data of sarcolipin in lipid membranes.Discovery of spiro-piperidine inhibitors and their modulation of the dynamics of the M2 proton channel from influenza A virus.Conformational heterogeneity of the M2 proton channel and a structural model for channel activation
P2860
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P2860
Backbone Structure of the Amantadine-Blocked Trans-Membrane Domain M2 Proton Channel from Influenza A Virus
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Backbone Structure of the Aman ...... Channel from Influenza A Virus
@ast
Backbone Structure of the Aman ...... Channel from Influenza A Virus
@en
Backbone Structure of the Aman ...... Channel from Influenza A Virus
@nl
type
label
Backbone Structure of the Aman ...... Channel from Influenza A Virus
@ast
Backbone Structure of the Aman ...... Channel from Influenza A Virus
@en
Backbone Structure of the Aman ...... Channel from Influenza A Virus
@nl
prefLabel
Backbone Structure of the Aman ...... Channel from Influenza A Virus
@ast
Backbone Structure of the Aman ...... Channel from Influenza A Virus
@en
Backbone Structure of the Aman ...... Channel from Influenza A Virus
@nl
P2093
P2860
P1433
P1476
Backbone Structure of the Aman ...... Channel from Influenza A Virus
@en
P2093
Conggang Li
Jack R Quine
Richard Bertram
Riqiang Fu
Srisairam Achuthan
Timothy A Cross
Tom Asbury
P2860
P304
P356
10.1529/BIOPHYSJ.106.090183
P407
P577
2007-06-15T00:00:00Z