pH-dependent tetramerization and amantadine binding of the transmembrane helix of M2 from the influenza A virus
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Backbone Structure of the Amantadine-Blocked Trans-Membrane Domain M2 Proton Channel from Influenza A VirusStructural basis for the function and inhibition of an influenza virus proton channelStructure of the amantadine binding site of influenza M2 proton channels in lipid bilayersExpression, folding, and proton transport activity of human uncoupling protein-1 (UCP1) in lipid membranes: evidence for associated functional formsA designed point mutant in Fis1 disrupts dimerization and mitochondrial fissionInfluenza M2 proton channelsAssembly of the m2 tetramer is strongly modulated by lipid chain length.Modeling the membrane environment has implications for membrane protein structure and function: influenza A M2 protein.Structural basis for proton conduction and inhibition by the influenza M2 protein.Cooperativity and specificity of association of a designed transmembrane peptide.Proton conduction through the M2 protein of the influenza A virus; a quantitative, mechanistic analysis of experimental data.Why bound amantadine fails to inhibit proton conductance according to simulations of the drug-resistant influenza A M2 (S31N).Solid-state NMR characterization of conformational plasticity within the transmembrane domain of the influenza A M2 proton channel.2D IR spectroscopy reveals the role of water in the binding of channel-blocking drugs to the influenza M2 channel.Proton Transport Mechanism of M2 Proton Channel Studied by Laser-Induced pH JumpSequence determinants of the energetics of folding of a transmembrane four-helix-bundle protein.Proton and cation transport activity of the M2 proton channel from influenza A virus.Biochemical and functional characterization of the Ebola virus VP24 protein: implications for a role in virus assembly and budding.NMR structures of the second transmembrane domain of the human glycine receptor alpha(1) subunit: model of pore architecture and channel gating.Proton conductance of influenza virus M2 protein in planar lipid bilayers.Proton association constants of His 37 in the Influenza-A M218-60 dimer-of-dimers.Computational study of drug binding to the membrane-bound tetrameric M2 peptide bundle from influenza A virusThe lipophilic bullet hits the targets: medicinal chemistry of adamantane derivativesUse of thiol-disulfide equilibria to measure the energetics of assembly of transmembrane helices in phospholipid bilayers.Functional reconstitution of influenza A M2(22-62).Histidines, heart of the hydrogen ion channel from influenza A virus: toward an understanding of conductance and proton selectivity.Tidal surge in the M2 proton channel, sensed by 2D IR spectroscopy.How do helix-helix interactions help determine the folds of membrane proteins? Perspectives from the study of homo-oligomeric helical bundles.Influence of solubilizing environments on membrane protein structuresComputational studies of proton transport through the M2 channel.Roles of the histidine and tryptophan side chains in the M2 proton channel from influenza A virus.Folding and self-association of atTic20 in lipid membranes: implications for understanding protein transport across the inner envelope membrane of chloroplasts.Mechanism of influenza A M2 transmembrane domain assembly in lipid membranesThe chemical and dynamical influence of the anti-viral drug amantadine on the M2 proton channel transmembrane domain.A peptide's perspective of water dynamicsA biophysical study on molecular physiology of the uncoupling proteins of the central nervous system.Proton transport through influenza A virus M2 protein reconstituted in vesicles.Amantadine-induced conformational and dynamical changes of the influenza M2 transmembrane proton channel.An unfolding story of helical transmembrane proteins.First principles design of a core bioenergetic transmembrane electron-transfer protein.
P2860
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P2860
pH-dependent tetramerization and amantadine binding of the transmembrane helix of M2 from the influenza A virus
description
2000 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2000
@ast
im November 2000 veröffentlicher wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2000/11/21)
@sk
vědecký článek publikovaný v roce 2000
@cs
wetenschappelijk artikel (gepubliceerd op 2000/11/21)
@nl
наукова стаття, опублікована в листопаді 2000
@uk
مقالة علمية (نشرت في 21-11-2000)
@ar
name
pH-dependent tetramerization a ...... M2 from the influenza A virus
@ast
pH-dependent tetramerization a ...... M2 from the influenza A virus
@en
pH-dependent tetramerization a ...... M2 from the influenza A virus
@nl
type
label
pH-dependent tetramerization a ...... M2 from the influenza A virus
@ast
pH-dependent tetramerization a ...... M2 from the influenza A virus
@en
pH-dependent tetramerization a ...... M2 from the influenza A virus
@nl
prefLabel
pH-dependent tetramerization a ...... M2 from the influenza A virus
@ast
pH-dependent tetramerization a ...... M2 from the influenza A virus
@en
pH-dependent tetramerization a ...... M2 from the influenza A virus
@nl
P2093
P2860
P3181
P356
P1433
P1476
pH-dependent tetramerization a ...... M2 from the influenza A virus
@en
P2093
B. R. Hill
J. D. Lear
W. F. DeGrado
P2860
P304
14160–14170
P3181
P356
10.1021/BI001799U
P407
P577
2000-11-21T00:00:00Z