Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase - Wikidata - thesis-toulmin - TriplyDB

Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase

Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase

http://www.wikidata.org/entity/Q27646401

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Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases Interaction of JMJD6 with single-stranded RNA RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases Distinct binding modes specify the recognition of methylated histones H3K4 and H4K20 by JMJD2A-tudor Histone demethylases in chromatin biology and beyond Physicochemical properties of cells and their effects on intrinsically disordered proteins (IDPs)Epigenetic regulation by histone demethylases in hypoxia The role of histone demethylases in cancer therapy KDM4/JMJD2 histone demethylases: epigenetic regulators in cancer cells Structure and function of dioxygenases in histone demethylation and DNA/RNA demethylation Histone demethylase KDM4B regulates otic vesicle invagination via epigenetic control of Dlx3 expression.Structural basis of a histone H3 lysine 4 demethylase required for stem elongation in rice Structural origins for the product specificity of SET domain protein methyltransferases Structural insights into a novel histone demethylase PHF8 Structural insights into a dual-specificity histone demethylase ceKDM7A from Caenorhabditis elegans Crystal structure of the catalytic core of Saccharomyces cerevesiae histone demethylase Rph1: insights into the substrate specificity and catalytic mechanism Quantitative High-Throughput Screening Identifies 8-Hydroxyquinolines as Cell-Active Histone Demethylase Inhibitors Inhibition of Histone Demethylases by 4-Carboxy-2,2′-Bipyridyl Compounds The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response Crystal Structure and Functional Analysis of JMJD5 Indicate an Alternate Specificity and Function Structural and Evolutionary Basis for the Dual Substrate Selectivity of Human KDM4 Histone Demethylase Family Structural basis for histone H3 Lys 27 demethylation by UTX/KDM6A Quaternary ammonium oxidative demethylation: X-ray crystallographic, resonance Raman, and UV-visible spectroscopic analysis of a Rieske-type demethylase An Analog of BIX-01294 Selectively Inhibits a Family of Histone H3 Lysine 9 Jumonji Demethylases Linking of 2-oxoglutarate and substrate binding sites enables potent and highly selective inhibition of JmjC histone demethylases The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases The PHD1 finger of KDM5B recognizes unmodified H3K4 during the demethylation of histone H3K4me2/3 by KDM5B A role for Saccharomyces cerevisiae Tpa1 protein in direct alkylation repair Epigenetic polypharmacology: from combination therapy to multitargeted drugs Inhibition of osteogenic differentiation of human adipose-derived stromal cells by retinoblastoma binding protein 2 repression of RUNX2-activated transcription Base excision repair facilitates a functional relationship between Guanine oxidation and histone demethylation Inhibition of 2-oxoglutarate dependent oxygenases PMeS: prediction of methylation sites based on enhanced feature encoding scheme Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease Distribution and prediction of catalytic domains in 2-oxoglutarate dependent dioxygenases.Modulation of epigenetic targets for anticancer therapy: clinicopathological relevance, structural data and drug discovery perspectives Development of homogeneous luminescence assays for histone demethylase catalysis and binding.Cation-π interactions of methylated ammonium ions: a quantum mechanical study.

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Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase

http://www.wikidata.org/entity/Q27646401

description

2007 nî lūn-bûn

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2007 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի օգոստոսին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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name

Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase

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Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase

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Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase

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Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase

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Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase

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Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase

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Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase

@ast

Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase

@en

Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase

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Nature Structural & Molecular Biology

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Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase

@en

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Evys Collazo

http://www.w3.org/2001/XMLSchema#string

Jean-François Couture

http://www.w3.org/2001/XMLSchema#string

Joseph S Brunzelle

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Patricia A Ortiz-Tello

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Raymond C Trievel

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P2860

Cooperative demethylation by JMJD2C and LSD1 promotes androgen receptor-dependent gene expression

The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases

LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription

JHDM2A, a JmjC-containing H3K9 demethylase, facilitates transcription activation by androgen receptor

Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases

Histone demethylation mediated by the nuclear amine oxidase homolog LSD1

Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair

The Trithorax group protein Lid is a trimethyl histone H3K4 demethylase required for dMyc-induced cell growth

Improved methods for building protein models in electron density maps and the location of errors in these models

Structure of HP1 chromodomain bound to a lysine 9-methylated histone H3 tail

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689-95

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scholarly article

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552520

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10.1038/NSMB1273

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8

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14

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2007-08-01T00:00:00Z

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232750973

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1005206585

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17589523

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