Human HDAC7 Harbors a Class IIa Histone Deacetylase-specific Zinc Binding Motif and Cryptic Deacetylase Activity - Wikidata - thesis-toulmin - TriplyDB

Human HDAC7 Harbors a Class IIa Histone Deacetylase-specific Zinc Binding Motif and Cryptic Deacetylase Activity

Human HDAC7 Harbors a Class IIa Histone Deacetylase-specific Zinc Binding Motif and Cryptic Deacetylase Activity

http://www.wikidata.org/entity/Q27649881

about

Structural and functional analysis of the human HDAC4 catalytic domain reveals a regulatory structural zinc-binding domain HDAC6 regulates mutant SOD1 aggregation through two SMIR motifs and tubulin acetylation The many roles of histone deacetylases in development and physiology: implications for disease and therapy Macrocyclic histone deacetylase inhibitors Identification of a better Homo sapiens Class II HDAC inhibitor through binding energy calculations and descriptor analysis Histone deacetylase 7 and FoxA1 in estrogen-mediated repression of RPRM HDAC8 substrates: Histones and beyond Small molecule inhibitors of zinc-dependent histone deacetylases Immune regulation by histone deacetylases: a focus on the alteration of FOXP3 activity HDAC6 as a target for neurodegenerative diseases: what makes it different from the other HDACs?New and emerging HDAC inhibitors for cancer treatment Structures of Metal-Substituted Human Histone Deacetylase 8 Provide Mechanistic Inferences on Biological Function,Structure of Prokaryotic Polyamine Deacetylase Reveals Evolutionary Functional Relationships with Eukaryotic Histone Deacetylases,Structural basis for the inhibition of histone deacetylase 8 (HDAC8), a key epigenetic player in the blood fluke Schistosoma mansoni Selective class IIa histone deacetylase inhibition via a nonchelating zinc-binding group Structural insights into HDAC6 tubulin deacetylation and its selective inhibition Profiling technologies for the identification and characterization of small-molecule histone deacetylase inhibitors Post-translational modifications regulate class IIa histone deacetylase (HDAC) function in health and disease Structural diversity of the epigenetics pocketome.Modulation of epigenetic targets for anticancer therapy: clinicopathological relevance, structural data and drug discovery perspectives Chemical phylogenetics of histone deacetylases.Genetic knock-down of HDAC7 does not ameliorate disease pathogenesis in the R6/2 mouse model of Huntington's disease Discovery of potent and selective histone deacetylase inhibitors via focused combinatorial libraries of cyclic alpha3beta-tetrapeptides.Vorinostat-like molecules as structural, stereochemical, and pharmacological tools Protein kinase D1 mediates class IIa histone deacetylase phosphorylation and nuclear extrusion in intestinal epithelial cells: role in mitogenic signaling Correlation between MMP-13 and HDAC7 expression in human knee osteoarthritis.Activation and inhibition of histone deacetylase 8 by monovalent cations.Transcriptional coregulators: fine-tuning metabolism.A novel class of small molecule inhibitors of HDAC6.Inhibition and mechanism of HDAC8 revisited.Histone deacetylase 9 (HDAC9) regulates the functions of the ATDC (TRIM29) protein.Manipulating protein acetylation in breast cancer: a promising approach in combination with hormonal therapies?Molecular modeling study on tunnel behavior in different histone deacetylase isoforms.Small-molecular modulators of cancer-associated epigenetic mechanisms.Chromatin remodeling in cardiovascular development and physiology.Histone deacetylase 4 alters cartilage homeostasis in human osteoarthritis.FOXP3+ regulatory T cell development and function require histone/protein deacetylase 3.Structure, mechanism, and inhibition of histone deacetylases and related metalloenzymes.Metabolism as a key to histone deacetylase inhibition.Mutagenesis Study Reveals the Rim of Catalytic Entry Site of HDAC4 and -5 as the Major Binding Surface of SMRT Corepressor

P2860

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P2860

Human HDAC7 Harbors a Class IIa Histone Deacetylase-specific Zinc Binding Motif and Cryptic Deacetylase Activity

http://www.wikidata.org/entity/Q27649881

description

2008 nî lūn-bûn

@nan

2008 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2008年の論文

@ja

2008年論文

@yue

2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

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2008年论文

@wuu

name

Human HDAC7 Harbors a Class II ...... d Cryptic Deacetylase Activity

@ast

Human HDAC7 Harbors a Class II ...... d Cryptic Deacetylase Activity

@en

Human HDAC7 Harbors a Class II ...... d Cryptic Deacetylase Activity

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type

label

Human HDAC7 Harbors a Class II ...... d Cryptic Deacetylase Activity

@ast

Human HDAC7 Harbors a Class II ...... d Cryptic Deacetylase Activity

@en

Human HDAC7 Harbors a Class II ...... d Cryptic Deacetylase Activity

@nl

prefLabel

Human HDAC7 Harbors a Class II ...... d Cryptic Deacetylase Activity

@ast

Human HDAC7 Harbors a Class II ...... d Cryptic Deacetylase Activity

@en

Human HDAC7 Harbors a Class II ...... d Cryptic Deacetylase Activity

@nl

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P2860

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P1433

Journal of Biological Chemistry

P1476

Human HDAC7 Harbors a Class II ...... d Cryptic Deacetylase Activity

@en

P2093

Alexander N Plotnikov

http://www.w3.org/2001/XMLSchema#string

Anja Schuetz

http://www.w3.org/2001/XMLSchema#string

Jinrong Min

http://www.w3.org/2001/XMLSchema#string

Michael Shuen

http://www.w3.org/2001/XMLSchema#string

Nick P Kwiatkowski

http://www.w3.org/2001/XMLSchema#string

Ralph Mazitschek

http://www.w3.org/2001/XMLSchema#string

Rebecca L Maglathin

http://www.w3.org/2001/XMLSchema#string

Thomas H McLean

http://www.w3.org/2001/XMLSchema#string

Timothy A Lewis

http://www.w3.org/2001/XMLSchema#string

P2860

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

Signal-dependent nuclear export of a histone deacetylase regulates muscle differentiation

Cloning and characterization of a histone deacetylase, HDAC9

Enzymatic activity associated with class II HDACs is dependent on a multiprotein complex containing HDAC3 and SMRT/N-CoR

HDAC6 is a microtubule-associated deacetylase

Class II histone deacetylases: versatile regulators

HDAC4, a human histone deacetylase related to yeast HDA1, is a transcriptional corepressor

Crystal structure of a eukaryotic zinc-dependent histone deacetylase, human HDAC8, complexed with a hydroxamic acid inhibitor

Isolation of a novel histone deacetylase reveals that class I and class II deacetylases promote SMRT-mediated repression

Histone deacetylase 3 interacts with and deacetylates myocyte enhancer factor 2

P304

11355-63

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scholarly article

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10.1074/JBC.M707362200

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P407

P433

17

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P478

283

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P50

Matthieu Schapira

Alexey Bochkarev

Abdellah Allali-Hassani

Cheryl Arrowsmith

P577

2008-04-25T00:00:00Z

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P698

18285338

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P921

P932

2431080

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