Structure of the integrin beta3 transmembrane segment in phospholipid bicelles and detergent micelles
about
Disruption of the integrin alphaLbeta2 transmembrane domain interface by beta2 Thr-686 mutation activates alphaLbeta2 and promotes micro-clustering of the alphaL subunitsThe structure of the integrin alphaIIbbeta3 transmembrane complex explains integrin transmembrane signallingThe magic of bicelles lights up membrane protein structureAnnular anionic lipids stabilize the integrin αIIbβ3 transmembrane complex.Structure of the Integrin IIb Transmembrane SegmentNMR solution conformations and interactions of integrin alphaLbeta2 cytoplasmic tailsThe structure of an integrin/talin complex reveals the basis of inside-out signal transduction.Structure of an integrin IIb 3 transmembrane-cytoplasmic heterocomplex provides insight into integrin activationBasic amino-acid side chains regulate transmembrane integrin signallingStructural model for the protein-translocating element of the twin-arginine transport systemIntegrin α1 Has a Long Helix, Extending from the Transmembrane Region to the Cytoplasmic Tail in Detergent MicellesOptimizing nanodiscs and bicelles for solution NMR studies of two β-barrel membrane proteins.Optimization of bicelle lipid composition and temperature for EPR spectroscopy of aligned membranesUnderstanding single-pass transmembrane receptor signaling from a structural viewpoint-what are we missing?Construction of covalent membrane protein complexes and high-throughput selection of membrane mimics.Characterization of the human sigma-1 receptor chaperone domain structure and binding immunoglobulin protein (BiP) interactionsThe GPIIb/IIIa (integrin alphaIIbbeta3) odyssey: a technology-driven saga of a receptor with twists, turns, and even a bend.Secondary structure, dynamics, and architecture of the p7 membrane protein from hepatitis C virus by NMR spectroscopy.L718P mutation in the membrane-proximal cytoplasmic tail of beta 3 promotes abnormal alpha IIb beta 3 clustering and lipid microdomain coalescence, and associates with a thrombasthenia-like phenotypeStructural basis of transmembrane domain interactions in integrin signaling.Structure elucidation of dimeric transmembrane domains of bitopic proteinsThe final steps of integrin activation: the end gameSpecificity for homooligomer versus heterooligomer formation in integrin transmembrane helicesStructural diversity in integrin/talin interactions.Transmembrane and cytoplasmic domains in integrin activation and protein-protein interactions (review).Tests of integrin transmembrane domain homo-oligomerization during integrin ligand binding and signalingDifferential repositioning of the second transmembrane helices from E. coli Tar and EnvZ upon moving the flanking aromatic residues.CW-EPR studies revealed different motional properties and oligomeric states of the integrin β1a transmembrane domain in detergent micelles or liposomesConformational changes in talin on binding to anionic phospholipid membranes facilitate signaling by integrin transmembrane helicesMultiscale simulations suggest a mechanism for integrin inside-out activation.A conserved amphipathic helix is required for membrane tubule formation by Yop1pInfluence of solubilizing environments on membrane protein structuresIntegrin αIIbβ3 transmembrane domain separation mediates bi-directional signaling across the plasma membrane.MolProbity for the masses-of data.Talin activates integrins by altering the topology of the β transmembrane domainMechanisms of Platelet Activation and Integrin αIIβ3.Localized lipid packing of transmembrane domains impedes integrin clustering.Interactions of platelet integrin alphaIIb and beta3 transmembrane domains in mammalian cell membranes and their role in integrin activationIntegrin signalling at a glance.Regulation of integrin activity and signalling
P2860
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P2860
Structure of the integrin beta3 transmembrane segment in phospholipid bicelles and detergent micelles
description
2008 nî lūn-bûn
@nan
2008 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Structure of the integrin beta ...... icelles and detergent micelles
@ast
Structure of the integrin beta ...... icelles and detergent micelles
@en
Structure of the integrin beta ...... icelles and detergent micelles
@nl
type
label
Structure of the integrin beta ...... icelles and detergent micelles
@ast
Structure of the integrin beta ...... icelles and detergent micelles
@en
Structure of the integrin beta ...... icelles and detergent micelles
@nl
prefLabel
Structure of the integrin beta ...... icelles and detergent micelles
@ast
Structure of the integrin beta ...... icelles and detergent micelles
@en
Structure of the integrin beta ...... icelles and detergent micelles
@nl
P2093
P356
P1433
P1476
Structure of the integrin beta ...... icelles and detergent micelles
@en
P2093
Anthony W Partridge
Mark H Ginsberg
Tobias S Ulmer
Tong-Lay Lau
P304
P356
10.1021/BI800107A
P407
P577
2008-04-01T00:00:00Z