Crystal structure of full-length KcsA in its closed conformation
about
Sodium channel molecular conformations and antiarrhythmic drug affinityMechanism of activation gating in the full-length KcsA K+ channelRole of the KcsA channel cytoplasmic domain in pH-dependent gatingDeep sequencing in library selection projects: what insight does it bring?Ion Concentration- and Voltage-Dependent Push and Pull Mechanisms of Potassium Channel Ion ConductionAllosteric control of ligand-binding affinity using engineered conformation-specific effector proteinsCrystal Structure of a Voltage-gated K+ Channel Pore Module in a Closed State in Lipid MembranesStructure of active β-arrestin-1 bound to a G-protein-coupled receptor phosphopeptideMutations that stabilize the open state of the Erwinia chrisanthemi ligand-gated ion channel fail to change the conformation of the pore domain in crystalsThe C-terminal helical bundle of the tetrameric prokaryotic sodium channel accelerates the inactivation rateConformational states and recognition of amyloidogenic peptides of human insulin-degrading enzymeStructure of a Prokaryotic Sodium Channel Pore Reveals Essential Gating Elements and an Outer Ion Binding Site Common to Eukaryotic ChannelsDeterminants of cation transport selectivity: Equilibrium binding and transport kineticsNanobodies and recombinant binders in cell biologyEngineering of recombinant crystallization chaperonesTuning the drug efflux activity of an ABC transporter in vivo by in vitro selected DARPin bindersProbing the energy landscape of activation gating of the bacterial potassium channel KcsAStructural and biophysical characterization of an epitope-specific engineered Fab fragment and complexation with membrane proteins: implications for co-crystallization.Membrane protein structure determination using crystallography and lipidic mesophases: recent advances and successes.Rapid identification of recombinant Fabs that bind to membrane proteins.The Protein Structure Initiative: achievements and visions for the future.Application of protein engineering to enhance crystallizability and improve crystal properties.Modeling and simulation of ion channels.The open gate structure of the membrane-embedded KcsA potassium channel viewed from the cytoplasmic sidePore hydration states of KcsA potassium channels in membranesFunctional reconstitution of a voltage-gated potassium channel in giant unilamellar vesicles.Synchrotron X-ray footprinting as a method to visualize water in proteins.Probing Structural Dynamics and Topology of the KCNE1 Membrane Protein in Lipid Bilayers via Site-Directed Spin Labeling and Electron Paramagnetic Resonance Spectroscopy.Generation and characterization of a chimeric rabbit/human Fab for co-crystallization of HIV-1 Rev.Rearrangements in the KcsA cytoplasmic domain underlie its gating.Lipid bilayer regulation of membrane protein function: gramicidin channels as molecular force probesA portable RNA sequence whose recognition by a synthetic antibody facilitates structural determination.Conversion of scFv peptide-binding specificity for crystal chaperone development.Generation of recombinant guinea pig antibody fragments to the human GABAC receptor.Beyond natural antibodies: the power of in vitro display technologies.Direct manipulation of a single potassium channel gate with an atomic force microscope probe.Calcium-dependent conformational changes in inositol trisphosphate receptors.Synchrotron radiation circular dichroism spectroscopy-defined structure of the C-terminal domain of NaChBac and its role in channel assembly.Structural investigation of the transmembrane domain of KCNE1 in proteoliposomesImportance of lipid-pore loop interface for potassium channel structure and function.
P2860
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P2860
Crystal structure of full-length KcsA in its closed conformation
description
2009 nî lūn-bûn
@nan
2009 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Crystal structure of full-length KcsA in its closed conformation
@ast
Crystal structure of full-length KcsA in its closed conformation
@en
Crystal structure of full-length KcsA in its closed conformation
@nl
type
label
Crystal structure of full-length KcsA in its closed conformation
@ast
Crystal structure of full-length KcsA in its closed conformation
@en
Crystal structure of full-length KcsA in its closed conformation
@nl
prefLabel
Crystal structure of full-length KcsA in its closed conformation
@ast
Crystal structure of full-length KcsA in its closed conformation
@en
Crystal structure of full-length KcsA in its closed conformation
@nl
P2093
P2860
P3181
P356
P1476
Crystal structure of full-length KcsA in its closed conformation
@en
P2093
Anthony Kossiakoff
Eduardo Perozo
Frederic A Fellouse
Kaori Esaki
Sachdev S Sidhu
Serdar Uysal
Valeria Vásquez
P2860
P304
P3181
P356
10.1073/PNAS.0810663106
P407
P577
2009-04-21T00:00:00Z