X-ray structure of a prokaryotic pentameric ligand-gated ion channel
about
A unified model of the GABA(A) receptor comprising agonist and benzodiazepine binding sitesGABRB3 mutation, G32R, associated with childhood absence epilepsy alters α1β3γ2L γ-aminobutyric acid type A (GABAA) receptor expression and channel gatingCrystal structures of free and antagonist-bound states of human α9 nicotinic receptor extracellular domainGABA A receptors: subtypes provide diversity of function and pharmacologyEnd-plate acetylcholine receptor: structure, mechanism, pharmacology, and diseaseThe Intracellular Loop of the Glycine Receptor: It's not all about the SizeIonotropic GABA receptor antagonism-induced adverse outcome pathways for potential neurotoxicity biomarkersNeuronal Nicotinic Acetylcholine Receptor Structure and Function and Response to NicotineIon channels gated by acetylcholine and serotonin: structures, biology, and drug discoveryThe concept of allosteric interaction and its consequences for the chemistry of the brainThe molecular pharmacology of volatile anestheticsThe impact of human hyperekplexia mutations on glycine receptor structure and functionThe nicotinic acetylcholine receptor: the founding father of the pentameric ligand-gated ion channel superfamilyStructure, function, and modulation of GABA(A) receptorsSize matters in activation/inhibition of ligand-gated ion channelsPathways and Barriers for Ion Translocation through the 5-HT3A Receptor ChannelExploring volatile general anesthetic binding to a closed membrane-bound bacterial voltage-gated sodium channel via computationDecrypting the sequence of structural events during the gating transition of pentameric ligand-gated ion channels based on an interpolated elastic network modelCrystal structure of a human GABAA receptorAn Ion Selectivity Filter in the Extracellular Domain of Cys-loop Receptors Reveals Determinants for Ion ConductanceStructure of a potentially open state of a proton-activated pentameric ligand-gated ion channelX-ray structure of a pentameric ligand-gated ion channel in an apparently open conformationCrystal structure of full-length KcsA in its closed conformationStructural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal α7 nicotinic acetylcholine receptorOne-microsecond molecular dynamics simulation of channel gating in a nicotinic receptor homologueNMR structure of the transmembrane domain of the n-acetylcholine receptor β2 subunitStructural basis of open channel block in a prokaryotic pentameric ligand-gated ion channelCrystal Structures of a Cysteine-modified Mutant in Loop D of Acetylcholine-binding ProteinPrinciples of activation and permeation in an anion-selective Cys-loop receptorLigand Activation of the Prokaryotic Pentameric Ligand-Gated Ion Channel ELICGating Movement of Acetylcholine Receptor Caught by Plunge-FreezingLigand-binding domain of an α7-nicotinic receptor chimera and its complex with agonistPentameric ligand-gated ion channel ELIC is activated by GABA and modulated by benzodiazepinesInhibition of the Prokaryotic Pentameric Ligand-Gated Ion Channel ELIC by Divalent CationsStructural and Functional Characterization of an Anesthetic Binding Site in the Second Cysteine-Rich Domain of Protein Kinase Cδ∗Multisite Binding of a General Anesthetic to the Prokaryotic Pentameric Erwinia chrysanthemi Ligand-gated Ion Channel (ELIC)NMR structure and dynamics of a designed water-soluble transmembrane domain of nicotinic acetylcholine receptorStructural basis for ion permeation mechanism in pentameric ligand-gated ion channelsStructural basis for potentiation by alcohols and anaesthetics in a ligand-gated ion channelNMR structures of the transmembrane domains of the α4β2 nAChR
P2860
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P2860
X-ray structure of a prokaryotic pentameric ligand-gated ion channel
description
2008 nî lūn-bûn
@nan
2008 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մարտին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
X-ray structure of a prokaryotic pentameric ligand-gated ion channel
@ast
X-ray structure of a prokaryotic pentameric ligand-gated ion channel
@en
X-ray structure of a prokaryotic pentameric ligand-gated ion channel
@nl
type
label
X-ray structure of a prokaryotic pentameric ligand-gated ion channel
@ast
X-ray structure of a prokaryotic pentameric ligand-gated ion channel
@en
X-ray structure of a prokaryotic pentameric ligand-gated ion channel
@nl
prefLabel
X-ray structure of a prokaryotic pentameric ligand-gated ion channel
@ast
X-ray structure of a prokaryotic pentameric ligand-gated ion channel
@en
X-ray structure of a prokaryotic pentameric ligand-gated ion channel
@nl
P3181
P356
P1433
P1476
X-ray structure of a prokaryotic pentameric ligand-gated ion channel
@en
P2093
Raimund Dutzler
Ricarda J C Hilf
P2888
P3181
P356
10.1038/NATURE06717
P407
P577
2008-03-20T00:00:00Z
P5875
P6179
1010031190