Structure of an integrin with an αI domain, complement receptor type 4
about
Structural basis for pure antagonism of integrin αVβ3 by a high-affinity form of fibronectinStructural specializations of α(4)β(7), an integrin that mediates rolling adhesionIntegrin-based therapeutics: biological basis, clinical use and new drugsMechanical regulation of T-cell functionsMolecular dynamics simulations of forced unbending of integrin α(v)β₃Closed headpiece of integrin IIb 3 and its complex with an IIb 3-specific antagonist that does not induce openingα(V)β(3) integrin crystal structures and their functional implicationsStructure of Collagen Receptor Integrin 1I Domain Carrying the Activating Mutation E317AShape change in the receptor for gliding motility in Plasmodium sporozoitesComplete integrin headpiece opening in eight stepsAn internal ligand-bound, metastable state of a leukocyte integrin, α X β 2Coordinated integrin activation by actin-dependent force during T-cell migrationBordetella adenylate cyclase toxin is a unique ligand of the integrin complement receptor 3Forcing switch from short- to intermediate- and long-lived states of the alphaA domain generates LFA-1/ICAM-1 catch bondsObserving force-regulated conformational changes and ligand dissociation from a single integrin on cells.Integrin α2β1 in nonactivated conformation can induce focal adhesion kinase signalingConformational stability analyses of alpha subunit I domain of LFA-1 and Mac-1Conservation of the human integrin-type beta-propeller domain in bacteria.Requirement of open headpiece conformation for activation of leukocyte integrin alphaXbeta2.Structural diversity in integrin/talin interactions.Modulation of integrin activation by an entropic spring in the {beta}-kneeIntegrin inside-out signaling and the immunological synapseCation-pi interaction regulates ligand-binding affinity and signaling of integrin alpha4beta7.EM structure of the ectodomain of integrin CD11b/CD18 and localization of its ligand-binding site relative to the plasma membrane.Metal ion and ligand binding of integrin α5β1FRET detection of lymphocyte function-associated antigen-1 conformational extension.The tail of integrin activation.Variation in one residue associated with the metal ion-dependent adhesion site regulates αIIbβ3 integrin ligand binding affinity.Intact alphaIIbbeta3 integrin is extended after activation as measured by solution X-ray scattering and electron microscopyEarly chordate origin of the vertebrate integrin αI domains.The C-terminal αI domain linker as a critical structural element in the conformational activation of αI integrinsRegulation of integrin affinity on cell surfacesProperties and prospects of adjuvants in influenza vaccination - messy precipitates or blessed opportunities?Molecular basis for complement recognition by integrin αXβ2.Identification, characterization, and epitope mapping of human monoclonal antibody J19 that specifically recognizes activated integrin α4β7.The regulation of integrin function by divalent cations.The Structure of a Full-length Membrane-embedded Integrin Bound to a Physiological LigandDynamic structural changes are observed upon collagen and metal ion binding to the integrin α1 I domain.Isoflurane binds and stabilizes a closed conformation of the leukocyte function-associated antigen-1.Three-Dimensional Structures of Full-Length, Membrane-Embedded Human α(IIb)β(3) Integrin Complexes
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P2860
Structure of an integrin with an αI domain, complement receptor type 4
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Structure of an integrin with an αI domain, complement receptor type 4
@ast
Structure of an integrin with an αI domain, complement receptor type 4
@en
Structure of an integrin with an αI domain, complement receptor type 4
@nl
type
label
Structure of an integrin with an αI domain, complement receptor type 4
@ast
Structure of an integrin with an αI domain, complement receptor type 4
@en
Structure of an integrin with an αI domain, complement receptor type 4
@nl
prefLabel
Structure of an integrin with an αI domain, complement receptor type 4
@ast
Structure of an integrin with an αI domain, complement receptor type 4
@en
Structure of an integrin with an αI domain, complement receptor type 4
@nl
P2093
P2860
P3181
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P1476
Structure of an integrin with an αI domain, complement receptor type 4
@en
P2093
Jianghai Zhu
Noritaka Nishida
Timothy A Springer
P2860
P304
P3181
P356
10.1038/EMBOJ.2009.367
P407
P577
2010-02-03T00:00:00Z