Requirement of open headpiece conformation for activation of leukocyte integrin alphaXbeta2.
about
A pH-regulated dimeric bouquet in the structure of von Willebrand factorStructural specializations of α(4)β(7), an integrin that mediates rolling adhesionAction and Traction: Cytoskeletal Control of Receptor Triggering at the Immunological SynapseLatent TGF-β structure and activationα(V)β(3) integrin crystal structures and their functional implicationsStructure of Collagen Receptor Integrin 1I Domain Carrying the Activating Mutation E317AComplete integrin headpiece opening in eight stepsHow Natalizumab Binds and Antagonizes 4 IntegrinsAn internal ligand-bound, metastable state of a leukocyte integrin, α X β 2Coordinated integrin activation by actin-dependent force during T-cell migrationHeterotropic modulation of selectin affinity by allosteric antibodies affects leukocyte rolling.Single-particle EM reveals plasticity of interactions between the adenovirus penton base and integrin αVβ3.F-actin flow drives affinity maturation and spatial organization of LFA-1 at the immunological synapse.Integrin inside-out signaling and the immunological synapseEpitope mapping for monoclonal antibody reveals the activation mechanism for αVβ3 integrin.The dendritic cell cytoskeleton promotes T cell adhesion and activation by constraining ICAM-1 mobilitySelective targeting of TGF-β activation to treat fibroinflammatory airway diseaseDistinct conformational spectrum of homologous multidrug ABC transporters.Unique structure of iC3b resolved at a resolution of 24 Å by 3D-electron microscopyIntact alphaIIbbeta3 integrin is extended after activation as measured by solution X-ray scattering and electron microscopyThe C-terminal αI domain linker as a critical structural element in the conformational activation of αI integrinsRegulation of integrin affinity on cell surfacesReconstruction of integrin activation.Molecular basis for complement recognition by integrin αXβ2.Sequence and structure relationships within von Willebrand factorThe Structure of a Full-length Membrane-embedded Integrin Bound to a Physiological LigandLinker regions and flexibility around the metalloprotease domain account for conformational activation of ADAMTS-13.The unique disulfide bond-stabilized W1 β4-β1 loop in the α4 β-propeller domain regulates integrin α4β7 affinity and signaling.Kindlin-3 Is Essential for the Resting α4β1 Integrin-mediated Firm Cell Adhesion under Shear Flow ConditionsLeukocyte arrest: Biomechanics and molecular mechanisms of β2 integrin activationRelating conformation to function in integrin α5β1.Transmembrane communication: general principles and lessons from the structure and function of the M2 proton channel, K⁺ channels, and integrin receptors.Guiding cell migration by tugging.The insider's guide to leukocyte integrin signalling and function.Integrin bi-directional signaling across the plasma membrane.Talin and kindlin: the one-two punch in integrin activation.Integrin function in vascular biology: a view from 2013.Phagocytosis: receptors, signal integration, and the cytoskeleton.Structural basis of blocking integrin activation and deactivation for anti-inflammationConformational equilibria and intrinsic affinities define integrin activation.
P2860
Q24324184-E155F315-7768-4813-A7B7-6209E477355CQ24611768-8A68FECC-6323-48CC-B3E4-4D00B5B3D044Q26751049-8D69464F-4629-47E8-8C76-3F6268D862CEQ27670456-1B062830-763C-4F07-A0C5-4CE4B422665FQ27674776-47D911F5-1275-4ECF-8231-5FD2651922FCQ27675239-C2B50FB5-3BA3-4176-9CCF-93FB9E18D319Q27678790-EA45520F-B874-43B5-B948-A676D91B9FD4Q27679979-214F455B-CA14-4BE4-A4E5-23745B0B36CEQ27681159-4E81356A-C30D-4DBF-8B10-ACAECE759D1FQ28822113-B1EA728D-EFB1-43E5-84EA-DA509ECCE698Q30571489-DF636004-D19B-4908-BDAC-EBC06DAD1417Q30581194-81296A5E-6A5D-4DB4-A692-C6751D8C52D3Q30620661-5E78626D-EF41-46D3-985E-2963BFAB40BCQ34237025-73068715-4451-446C-9308-003CFC146527Q34805008-25FE0EF2-B58B-420F-BE7A-5518F8B9D195Q35094278-FC58FF09-AB99-4AD5-9223-8D32A3BCD611Q35125022-E337374D-B26F-4D08-9CDB-D8010BB560ECQ35152093-3CDDDB84-8630-4B7F-B518-C23EDDFA7B18Q35164659-8B3EF201-D606-461C-8D5F-4D4E9D8751C2Q35266840-69F0ECDA-3F24-4923-AB13-A8078AFDD9DAQ35605015-AC352FCD-9B73-45F2-9143-5305BC823D71Q35626360-B9A7A8AF-17A3-488D-87B6-BA2041D15047Q35651723-9CC40583-6B72-4E55-9701-867DA4051656Q35849584-294D8238-1094-485F-BB85-52937D0DA0B7Q36100466-52D3FFC9-82BF-4761-A466-966F792F45C2Q36283927-46EE19EA-FFC0-447B-964D-5E41E1FF9E95Q36652558-FAFE9AFA-C2F5-4ADC-9895-71EAB07B9426Q36850278-982ACE2B-B87A-4595-85A3-DB2E6A80E61DQ36876257-D46AA1C4-63BA-4C49-AA3E-2138C44455BEQ36908674-C201A479-754F-4C89-A7F9-BE5A69814ADEQ37086651-94DD43AE-03B1-47FD-8670-29CE38F91497Q37156475-7B887BBB-C548-460D-ABBD-1B5D3F78050AQ37307604-EE7ED5B5-87DA-46C0-BADB-49A0166B030BQ37877543-5C0A2406-06F6-4E6E-8E32-0A1B1E5BD062Q38024314-00BD0FED-B229-409D-9932-6159FFFF0DE0Q38183284-2E57325C-8DEC-4D99-97C3-2FF1EAD97F58Q38195715-4A1592AC-B5A8-4ED1-8C48-770E865BB475Q38260571-71512F99-73A0-40B1-862C-247A15F26132Q38543641-C596C003-A587-46A3-AA64-EB5117E6901FQ38719428-DD6F6B53-627E-45EB-ACDD-D860B6129540
P2860
Requirement of open headpiece conformation for activation of leukocyte integrin alphaXbeta2.
description
2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Requirement of open headpiece ...... eukocyte integrin alphaXbeta2.
@ast
Requirement of open headpiece ...... eukocyte integrin alphaXbeta2.
@en
Requirement of open headpiece ...... eukocyte integrin alphaXbeta2.
@nl
type
label
Requirement of open headpiece ...... eukocyte integrin alphaXbeta2.
@ast
Requirement of open headpiece ...... eukocyte integrin alphaXbeta2.
@en
Requirement of open headpiece ...... eukocyte integrin alphaXbeta2.
@nl
prefLabel
Requirement of open headpiece ...... eukocyte integrin alphaXbeta2.
@ast
Requirement of open headpiece ...... eukocyte integrin alphaXbeta2.
@en
Requirement of open headpiece ...... eukocyte integrin alphaXbeta2.
@nl
P2093
P2860
P356
P1476
Requirement of open headpiece ...... eukocyte integrin alphaXbeta2.
@en
P2093
Noritaka Nishida
Thomas Walz
Timothy A Springer
P2860
P304
14727-14732
P356
10.1073/PNAS.1008663107
P407
P577
2010-08-02T00:00:00Z