A 1.9 A crystal structure of the HDV ribozyme precleavage suggests both Lewis acid and general acid mechanisms contribute to phosphodiester cleavage
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HDV-like self-cleaving ribozymesIdentification of an hepatitis delta virus-like ribozyme at the mRNA 5'-end of the L1Tc retrotransposon from Trypanosoma cruziEvolution of the R2 retrotransposon ribozyme and its self-cleavage siteThe structural basis of RNA-catalyzed RNA polymerization.NMR Localization of Divalent Cations at the Active Site of the Neurospora VS Ribozyme Provides Insights into RNA–Metal-Ion InteractionsSolution structure and metal ion binding sites of the human CPEB3 ribozyme's P4 domainCrystal structure and mechanistic investigation of the twister ribozymeChemistry and Biology of Self-Cleaving RibozymesCharacterization of the trans Watson-Crick GU base pair located in the catalytic core of the antigenomic HDV ribozymePrevalence of syn nucleobases in the active sites of functional RNAsA Two-Metal-Ion-Mediated Conformational Switching Pathway for HDV Ribozyme ActivationQuantum mechanical/molecular mechanical free energy simulations of the self-cleavage reaction in the hepatitis delta virus ribozyme.Intrinsic acid-base properties of a hexa-2'-deoxynucleoside pentaphosphate, d(ApGpGpCpCpT): neighboring effects and isomeric equilibria.Do the hairpin and VS ribozymes share a common catalytic mechanism based on general acid-base catalysis? A critical assessment of available experimental data.Disparate HDV ribozyme crystal structures represent intermediates on a rugged free-energy landscape.Long-distance communication in the HDV ribozyme: insights from molecular dynamics and experimentsNew tools provide a second look at HDV ribozyme structure, dynamics and cleavage.The role of an active site Mg(2+) in HDV ribozyme self-cleavage: insights from QM/MM calculations.Base ionization and ligand binding: how small ribozymes and riboswitches gain a foothold in a protein world.Raman characterization of Avocado Sunblotch viroid and its response to external perturbations and self-cleavage.Linear free energy relationships in RNA transesterification: theoretical models to aid experimental interpretationsCharacterization of the Structure and Dynamics of the HDV Ribozyme at Different Stages Along the Reaction Path.Constant pH Molecular Dynamics Simulations of Nucleic Acids in Explicit Solvent.Processing and translation initiation of non-long terminal repeat retrotransposons by hepatitis delta virus (HDV)-like self-cleaving ribozymesAssessment of metal-assisted nucleophile activation in the hepatitis delta virus ribozyme from molecular simulation and 3D-RISM.Two Divalent Metal Ions and Conformational Changes Play Roles in the Hammerhead Ribozyme Cleavage Reaction.Multiscale methods for computational RNA enzymology.Transition State Features in the Hepatitis Delta Virus Ribozyme Reaction Revealed by Atomic Perturbations.Lewis acid catalysis of phosphoryl transfer from a copper(II)-NTP complex in a kinase ribozyme.pH-dependent dynamics of complex RNA macromoleculesSecondary structure confirmation and localization of Mg2+ ions in the mammalian CPEB3 ribozyme.Molecular Dynamics Study of Twister Ribozyme: Role of Mg(2+) Ions and the Hydrogen-Bonding Network in the Active Site.Two distinct catalytic strategies in the hepatitis δ virus ribozyme cleavage reaction.The DNA and RNA sugar-phosphate backbone emerges as the key player. An overview of quantum-chemical, structural biology and simulation studies.Nucleic acid catalysis: metals, nucleobases, and other cofactors.Mapping the interactions of selected antibiotics and their Cu2+ complexes with the antigenomic δ ribozyme.Model for the Functional Active State of the TS Ribozyme from Molecular Simulation.Strategies for Characterization of Enzymatic Nucleic Acids.Structural and Biochemical Properties of Novel Self-Cleaving Ribozymes.The structure of a nucleolytic ribozyme that employs a catalytic metal ion.
P2860
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P2860
A 1.9 A crystal structure of the HDV ribozyme precleavage suggests both Lewis acid and general acid mechanisms contribute to phosphodiester cleavage
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2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
A 1.9 A crystal structure of t ...... ute to phosphodiester cleavage
@ast
A 1.9 A crystal structure of t ...... ute to phosphodiester cleavage
@en
A 1.9 A crystal structure of t ...... ute to phosphodiester cleavage
@nl
type
label
A 1.9 A crystal structure of t ...... ute to phosphodiester cleavage
@ast
A 1.9 A crystal structure of t ...... ute to phosphodiester cleavage
@en
A 1.9 A crystal structure of t ...... ute to phosphodiester cleavage
@nl
prefLabel
A 1.9 A crystal structure of t ...... ute to phosphodiester cleavage
@ast
A 1.9 A crystal structure of t ...... ute to phosphodiester cleavage
@en
A 1.9 A crystal structure of t ...... ute to phosphodiester cleavage
@nl
P2093
P3181
P356
P1433
P1476
A 1.9 A crystal structure of t ...... ute to phosphodiester cleavage
@en
P2093
Durga M Chadalavada
Elaine Chase
Jui-Hui Chen
Philip C Bevilacqua
Rieko Yajima
P304
P3181
P356
10.1021/BI100670P
P407
P577
2010-08-10T00:00:00Z