Design and synthesis of inhaled p38 inhibitors for the treatment of chronic obstructive pulmonary disease
about
Interrelated role of cigarette smoking, oxidative stress, and immune response in COPD and corresponding treatmentsApplications of chemogenomic library screening in drug discoveryUnderstanding ligand-receptor non-covalent binding kinetics using molecular modeling.The discovery of potent, selective, and reversible inhibitors of the house dust mite peptidase allergen Der p 1: an innovative approach to the treatment of allergic asthmaComparison of the anti-inflammatory effects of Cilomilast, Budesonide and a p38 Mitogen activated protein kinase inhibitor in COPD lung tissue macrophages.Translating slow-binding inhibition kinetics into cellular and in vivo effectsImpact of CYP1A1 Polymorphisms on Susceptibility to Chronic Obstructive Pulmonary Disease: A Meta-AnalysisSlow inhibition and conformation selective properties of extracellular signal-regulated kinase 1 and 2 inhibitorsDifferential expression of p38 MAPK α, β, γ, δ isoforms in nucleus pulposus modulates macrophage polarization in intervertebral disc degeneration.Macrophage Migration Inhibitory Factor: A Novel Inhibitor of Apoptosis Signal-Regulating Kinase 1-p38-Xanthine Oxidoreductase-Dependent Cigarette Smoke-Induced Apoptosis.Cell host response to infection with novel human coronavirus EMC predicts potential antivirals and important differences with SARS coronavirusEmerging drugs for chronic obstructive pulmonary disease.p38 MAPK inhibitors, IKK2 inhibitors, and TNFα inhibitors in COPD.New anti-inflammatory targets for chronic obstructive pulmonary disease.p38 MAPK inhibitors: a patent review (2012 - 2013).TAK1 selective inhibition: state of the art and future opportunities.Investigational p38 inhibitors for the treatment of chronic obstructive pulmonary disease.Synthesis and p38 Inhibitory Activity of Some Novel Substituted N,N'-Diarylurea Derivatives.First comprehensive structural and biophysical analysis of MAPK13 inhibitors targeting DFG-in and DFG-out binding modes.Modern advances in heterocyclic chemistry in drug discovery.Kinases as Novel Therapeutic Targets in Asthma and Chronic Obstructive Pulmonary Disease.Design, Synthesis and Biological Evaluation of Novel Substituted N,N'-Diaryl ureas as Potent p38 Inhibitors.Assessing the similarity of ligand binding conformations with the Contact Mode Score.TAK1 inhibition in the DFG-out conformation.Respivert's multikinase inhibitors, an evaluation of WO2014033446 to WO2014033449.Ginsenosides from Korean Red Ginseng ameliorate lung inflammatory responses: inhibition of the MAPKs/NF-κB/c-Fos pathways
P2860
Q27023723-9C99DA16-3B63-4325-9AB7-88C2B7384174Q28656335-50E2291D-340D-4ED6-8A93-07813C54DB2CQ33796500-5B016E2B-6847-4470-B633-D5CD2E8A0397Q34446046-D37767CF-8CB2-4D44-88E4-08C380934415Q34475700-12B4B8FB-6921-46BF-94AF-21CF104F3DD5Q35954896-3B915B5D-10D5-44A7-AE9A-71998C5AE3FBQ36070482-51157D70-0ED0-4DD6-8FB9-9554B04011F4Q36493862-04C20C12-8CD5-4A2C-8730-FA4ABBF21A69Q36615693-666EF9CC-07E8-4843-A5E2-5CEC883B2A37Q36765952-CEC82388-95C0-49C5-929D-87BE532D5D6FQ36872701-B082A59E-24A1-4C8A-B82C-A41378AD7B61Q37984088-6F4F326F-7BB1-4E56-94A8-284F7C51C74EQ37988188-24E9EA5B-5B5F-4296-8198-36E43135AB8DQ38131512-5CB5685C-29E9-4FF0-90A2-DECE6BDE43E5Q38194600-C06C7872-155C-4EEA-BBB9-254EDB0BF515Q38315867-5CEBDD28-4BA9-4F41-8A7C-35D191A098EBQ38323383-B8B49985-1CA1-45A9-AF87-1D76A2069BE8Q38768553-B95BFD24-81D2-42EC-A1F8-3A65670C6B95Q38846155-DC5E083C-4C0A-4980-91CF-8085115F801BQ38860432-80718C24-863F-4E47-8B35-DDE2C4B43860Q38882099-B9719617-7625-44E6-9449-54B00D036320Q38963029-81E0E2DB-BF94-45ED-80D1-46E3BC6DBAF2Q41638503-11C82AD9-B393-48DE-8544-4860E82FC84FQ45352917-A0D2B79F-F918-42B9-9DD0-8593486C433DQ54309065-85C2A071-8008-4C05-82AC-4503631EDCDEQ58595408-3B2CA76C-2C52-478C-B5EA-FED7F5E4452C
P2860
Design and synthesis of inhaled p38 inhibitors for the treatment of chronic obstructive pulmonary disease
description
2011 nî lūn-bûn
@nan
2011 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Design and synthesis of inhale ...... obstructive pulmonary disease
@ast
Design and synthesis of inhale ...... obstructive pulmonary disease
@en
Design and synthesis of inhale ...... obstructive pulmonary disease
@nl
type
label
Design and synthesis of inhale ...... obstructive pulmonary disease
@ast
Design and synthesis of inhale ...... obstructive pulmonary disease
@en
Design and synthesis of inhale ...... obstructive pulmonary disease
@nl
prefLabel
Design and synthesis of inhale ...... obstructive pulmonary disease
@ast
Design and synthesis of inhale ...... obstructive pulmonary disease
@en
Design and synthesis of inhale ...... obstructive pulmonary disease
@nl
P2093
P356
P1476
Design and synthesis of inhale ...... obstructive pulmonary disease
@en
P2093
Arnaud Lemaitre
Axel Mahnke
Christopher Phillips
David A Fairman
David S Millan
Iain C Kilty
James Philip
Jane L Burrows
John P Mathias
Kenneth J Butcher
P304
P356
10.1021/JM200677B
P407
P577
2011-11-24T00:00:00Z