Structure of the human P2Y12 receptor in complex with an antithrombotic drug
about
G Protein-Coupled Receptors (GPCRs) in Alzheimer's Disease: A Focus on BACE1 Related GPCRsPersonalized antiplatelet therapy with P2Y12 receptor inhibitors: benefits and pitfallsStructural Studies of G Protein-Coupled ReceptorsBlood cells: an historical account of the roles of purinergic signallingMinireview: From the bench, toward the clinic: therapeutic opportunities for cannabinoid receptor modulationPost-expression strategies for structural investigations of membrane proteins.G-protein-coupled receptors signaling pathways in new antiplatelet drug developmentLarge-scale production and protein engineering of G protein-coupled receptors for structural studiesStructure-Based Design of 3-(4-Aryl-1H-1,2,3-triazol-1-yl)-Biphenyl Derivatives as P2Y14 Receptor Antagonists.Modeling ligand recognition at the P2Y12 receptor in light of X-ray structural information.Agonist-bound structure of the human P2Y12 receptorMembrane-Mediated Oligomerization of G Protein Coupled Receptors and Its Implications for GPCR FunctionP2Y12 receptors: structure and functionStructure-Based Sequence Alignment of the Transmembrane Domains of All Human GPCRs: Phylogenetic, Structural and Functional ImplicationsSequence, structure and ligand binding evolution of rhodopsin-like G protein-coupled receptors: a crystal structure-based phylogenetic analysisStructural-Functional Features of the Thyrotropin Receptor: A Class A G-Protein-Coupled Receptor at WorkEffects of 4(1H)-quinolinone derivative, a novel non-nucleotide allosteric purinergic P2Y 2 agonist, on cardiomyocytes in neonatal rats.Allosteric sodium in class A GPCR signalingRare platelet GPCR variants: what can we learn?Nucleotide signalling during inflammationTwo disparate ligand-binding sites in the human P2Y1 receptor.Two classes of cholesterol binding sites for the β2AR revealed by thermostability and NMR.Exploring a 2-naphthoic acid template for the structure-based design of P2Y14 receptor antagonist molecular probesIdentification of a new dysfunctional platelet P2Y12 receptor variant associated with bleeding diathesis.Structural characterization of triple transmembrane domain containing fragments of a yeast G protein-coupled receptor in an organic : aqueous environment by solution-state NMR spectroscopyIdentification of destabilizing and stabilizing mutations of Ste2p, a G protein-coupled receptor in Saccharomyces cerevisiae.John Daly Lecture: Structure-guided Drug Design for Adenosine and P2Y ReceptorsTargeting renal purinergic signalling for the treatment of lithium-induced nephrogenic diabetes insipidus.Quantifying conformational changes in GPCRs: glimpse of a common functional mechanism.A Novel Screening Approach for Optimal and Functional Fusion of T4 Lysozyme in GPCRs.From G Protein-coupled Receptor Structure Resolution to Rational Drug Design.Molecular Insights into the Transmembrane Domain of the Thyrotropin ReceptorDistinct Agonist Regulation of Muscarinic Acetylcholine M2-M3 Heteromers and Their Corresponding Homomers.Medicinal chemistry of adenosine, P2Y and P2X receptors.Nucleotides Acting at P2Y Receptors: Connecting Structure and Function.Identification of a small-molecule ligand that activates the neuropeptide receptor GPR171 and increases food intake.Opioid receptors: Structural and mechanistic insights into pharmacology and signaling.Identification of a New Morpholine Scaffold as a P2Y12 Receptor Antagonist.Thioredoxin Inhibitors Attenuate Platelet Function and Thrombus Formation.Design, synthesis, pharmacological characterization of a fluorescent agonist of the P2Y₁₄ receptor.
P2860
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P2860
Structure of the human P2Y12 receptor in complex with an antithrombotic drug
description
2014 nî lūn-bûn
@nan
2014 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Structure of the human P2Y12 receptor in complex with an antithrombotic drug
@ast
Structure of the human P2Y12 receptor in complex with an antithrombotic drug
@en
Structure of the human P2Y12 receptor in complex with an antithrombotic drug
@nl
type
label
Structure of the human P2Y12 receptor in complex with an antithrombotic drug
@ast
Structure of the human P2Y12 receptor in complex with an antithrombotic drug
@en
Structure of the human P2Y12 receptor in complex with an antithrombotic drug
@nl
prefLabel
Structure of the human P2Y12 receptor in complex with an antithrombotic drug
@ast
Structure of the human P2Y12 receptor in complex with an antithrombotic drug
@en
Structure of the human P2Y12 receptor in complex with an antithrombotic drug
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
Structure of the human P2Y12 receptor in complex with an antithrombotic drug
@en
P2093
Dandan Zhang
Evgeny Kiselev
Gustavo Fenalti
Gye Won Han
Huaiyu Yang
Hualiang Jiang
Qiang Zhao
P2860
P2888
P3181
P356
10.1038/NATURE13083
P407
P50
P577
2014-05-01T00:00:00Z
P6179
1018280867