Crystal structure of human CDC7 kinase in complex with its activator DBF4
about
A conserved water-mediated hydrogen bond network defines bosutinib's kinase selectivityMolecular Features of Product Release for the PKA Catalytic CycleThe potent Cdc7-Dbf4 (DDK) kinase inhibitor XL413 has limited activity in many cancer cell lines and discovery of potential new DDK inhibitor scaffoldsDDK dependent regulation of TOP2A at centromeres revealed by a chemical genetics approachThe role of Dbf4-dependent protein kinase in DNA polymerase ζ-dependent mutagenesis in Saccharomyces cerevisiae.MiR-630 inhibits proliferation by targeting CDC7 kinase, but maintains the apoptotic balance by targeting multiple modulators in human lung cancer A549 cells.Characterization of a Drosophila ortholog of the Cdc7 kinase: a role for Cdc7 in endoreplication independent of Chiffon.Dbf4: the whole is greater than the sum of its partsCdc7-dependent and -independent phosphorylation of Claspin in the induction of the DNA replication checkpointThe Gpr1/Zdbf2 locus provides new paradigms for transient and dynamic genomic imprinting in mammals.Cdk1-mediated phosphorylation of Cdc7 suppresses DNA re-replicationp53 controls CDC7 levels to reinforce G1 cell cycle arrest upon genotoxic stress.Xenopus Cdc7 executes its essential function early in S phase and is counteracted by checkpoint-regulated protein phosphatase 1.Reversal of DDK-Mediated MCM Phosphorylation by Rif1-PP1 Regulates Replication Initiation and Replisome Stability Independently of ATR/Chk1.Localization of Cdc7 Protein Kinase During DNA Replication in Saccharomyces cerevisiae.Histone H4K20 methylation mediated chromatin compaction threshold ensures genome integrity by limiting DNA replication licensing
P2860
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P2860
Crystal structure of human CDC7 kinase in complex with its activator DBF4
description
2012 nî lūn-bûn
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2012 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Crystal structure of human CDC7 kinase in complex with its activator DBF4
@ast
Crystal structure of human CDC7 kinase in complex with its activator DBF4
@en
Crystal structure of human CDC7 kinase in complex with its activator DBF4
@nl
type
label
Crystal structure of human CDC7 kinase in complex with its activator DBF4
@ast
Crystal structure of human CDC7 kinase in complex with its activator DBF4
@en
Crystal structure of human CDC7 kinase in complex with its activator DBF4
@nl
prefLabel
Crystal structure of human CDC7 kinase in complex with its activator DBF4
@ast
Crystal structure of human CDC7 kinase in complex with its activator DBF4
@en
Crystal structure of human CDC7 kinase in complex with its activator DBF4
@nl
P2093
P2860
P3181
P356
P1476
Crystal structure of human CDC7 kinase in complex with its activator DBF4
@en
P2093
Andrea Di Fonzo
Frédéric Elustondo
Frédéric G Leroux
Siobhan Hughes
Stephen J Matthews
P2860
P2888
P304
P3181
P356
10.1038/NSMB.2404
P577
2012-11-01T00:00:00Z
P5875
P6179
1019162678