MDM2 is an important prognostic and predictive factor for platin-pemetrexed therapy in malignant pleural mesotheliomas and deregulation of P14/ARF (encoded by CDKN2A) seems to contribute to an MDM2-driven inactivation of P53.

MDM2 is an important prognostic and predictive factor for platin-pemetrexed therapy in malignant pleural mesotheliomas and deregulation of P14/ARF (encoded by CDKN2A) seems to contribute to an MDM2-driven inactivation of P53.

Item
http://www.wikidata.org/entity/Q27853125
CIViC databaseMDM2 and HIF1alpha expression levels in different histologic subtypes of malignant pleural mesothelioma: correlation with pathological and clinical data.Screening of Pleural Mesotheliomas for DNA-damage Repair Players by Digital Gene Expression Analysis Can Enhance Clinical Management of Patients Receiving Platin-Based Chemotherapy.Novel insights into mesothelioma biology and implications for therapy.miRNA regulation is important for DNA damage repair and recognition in malignant pleural mesothelioma.Simultaneous, Single-Cell Measurement of Messenger RNA, Cell Surface Proteins, and Intracellular Proteins.Large-scale copy number analysis reveals variations in genes not previously associated with malignant pleural mesothelioma.Methylation of L1RE1, RARB, and RASSF1 function as possible biomarkers for the differential diagnosis of lung cancer.Immunohistochemically detectable metallothionein expression in malignant pleural mesotheliomas is strongly associated with early failure to platin-based chemotherapy.The Roles of MDM2 and MDMX in Cancer.Inhibition of MDM2 via Nutlin-3A: A Potential Therapeutic Approach for Pleural Mesotheliomas with MDM2-Induced Inactivation of Wild-Type P53
P2860

MDM2 is an important prognostic and predictive factor for platin-pemetrexed therapy in malignant pleural mesotheliomas and deregulation of P14/ARF (encoded by CDKN2A) seems to contribute to an MDM2-driven inactivation of P53.

Item
http://www.wikidata.org/entity/Q27853125
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MDM2 is an important prognosti ...... M2-driven inactivation of P53.
@ast
MDM2 is an important prognosti ...... M2-driven inactivation of P53.
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MDM2 is an important prognosti ...... M2-driven inactivation of P53.
@nl
type
label
MDM2 is an important prognosti ...... M2-driven inactivation of P53.
@ast
MDM2 is an important prognosti ...... M2-driven inactivation of P53.
@en
MDM2 is an important prognosti ...... M2-driven inactivation of P53.
@nl
altLabel
MDM2 is an important prognosti ...... DM2-driven inactivation of P53
@en
prefLabel
MDM2 is an important prognosti ...... M2-driven inactivation of P53.
@ast
MDM2 is an important prognosti ...... M2-driven inactivation of P53.
@en
MDM2 is an important prognosti ...... M2-driven inactivation of P53.
@nl
P1433
P1476
P2093
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P50
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P5875
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MDM2 is an important prognosti ...... DM2-driven inactivation of P53
@en
P2093
P2860
P2888
P304
P31
P3181
P356
P407
P433
P478
P50
P577
P5875
P6179
P698
P932