PTK6 inhibits down-regulation of EGF receptor through phosphorylation of ARAP1
about
Regulators and Effectors of Arf GTPases in NeutrophilsARAP1 regulates the ring size of circular dorsal ruffles through Arf1 and Arf5.The associated pyrazolopyrimidines PP1 and PP2 inhibit protein tyrosine kinase 6 activity and suppress breast cancer cell proliferation.Evolution of breast cancer therapeutics: Breast tumour kinase's role in breast cancer and hope for breast tumour kinase targeted therapyGenomic and genetic characterization of cholangiocarcinoma identifies therapeutic targets for tyrosine kinase inhibitorsBRK targets Dok1 for ubiquitin-mediated proteasomal degradation to promote cell proliferation and migration.ArfGAPs: key regulators for receptor sorting.Brk/PTK6 sustains activated EGFR signaling through inhibiting EGFR degradation and transactivating EGFRSuppressor of cytokine signaling 3 inhibits breast tumor kinase activation of STAT3.Protein-tyrosine phosphatase 1B antagonized signaling by insulin-like growth factor-1 receptor and kinase BRK/PTK6 in ovarian cancer cells.Hsp90 rescues PTK6 from proteasomal degradation in breast cancer cells.CagA phosphorylation-dependent MMP-9 expression in gastric epithelial cells.Breast tumor kinase (Brk/PTK6) plays a role in the differentiation of primary keratinocytes.Signaling by PTK6PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1PTK6 Localized at the Plasma Membrane Promotes Cell Proliferation and MigratiOn Through Phosphorylation of Eps8.PTK6 binds ARAP1PTK6 phosphorylates ARAP1
P2860
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P2860
PTK6 inhibits down-regulation of EGF receptor through phosphorylation of ARAP1
description
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2010
@ast
im August 2010 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2010/08/20)
@sk
vědecký článek publikovaný v roce 2010
@cs
wetenschappelijk artikel (gepubliceerd op 2010/08/20)
@nl
наукова стаття, опублікована в серпні 2010
@uk
name
PTK6 inhibits down-regulation of EGF receptor through phosphorylation of ARAP1
@ast
PTK6 inhibits down-regulation of EGF receptor through phosphorylation of ARAP1
@en
PTK6 inhibits down-regulation of EGF receptor through phosphorylation of ARAP1
@nl
type
label
PTK6 inhibits down-regulation of EGF receptor through phosphorylation of ARAP1
@ast
PTK6 inhibits down-regulation of EGF receptor through phosphorylation of ARAP1
@en
PTK6 inhibits down-regulation of EGF receptor through phosphorylation of ARAP1
@nl
prefLabel
PTK6 inhibits down-regulation of EGF receptor through phosphorylation of ARAP1
@ast
PTK6 inhibits down-regulation of EGF receptor through phosphorylation of ARAP1
@en
PTK6 inhibits down-regulation of EGF receptor through phosphorylation of ARAP1
@nl
P2093
P2860
P921
P356
P1476
PTK6 inhibits down-regulation of EGF receptor through phosphorylation of ARAP1
@en
P2093
Eun-Saem Lee
Hye-Young Yoon
Paul A. Randazzo
Seung-Taek Lee
Shin-Ae Kang
P2860
P304
26013–26021
P356
10.1074/JBC.M109.088971
P407
P577
2010-08-20T00:00:00Z